Interleukin-6 dependent induction of the cyclin dependent kinase inhibitor p21WAF1/CIP1 is lost during progression of human malignant melanoma

Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma

Investigational New Drugs ◽

10.1023/b:drug.0000026258.02846.1c ◽

2004 ◽

Vol 22 (3) ◽

pp. 315-322 ◽

Cited By ~ 54

Author(s):

Susan Burdette-Radoux ◽

Richard G. Tozer ◽

Reinhard C. Lohmann ◽

Ian Quirt ◽

D. Scott Ernst ◽

...

Keyword(s):

Malignant Melanoma ◽

Phase Ii ◽

Kinase Inhibitor ◽

Phase Ii Trial ◽

Metastatic Malignant Melanoma ◽

Cyclin Dependent Kinase ◽

Interleukin–6 ( IL-6 ) rs1800796 and cyclin dependent kinase inhibitor ( CDKN2A/CDKN2B ) rs2383207 are associated with ischemic stroke in indigenous West African Men

Journal of the Neurological Sciences ◽

10.1016/j.jns.2017.05.046 ◽

2017 ◽

Vol 379 ◽

pp. 229-235 ◽

Cited By ~ 12

Author(s):

Rufus Akinyemi ◽

Donna K. Arnett ◽

Hemant K. Tiwari ◽

Bruce Ovbiagele ◽

Fred Sarfo ◽

...

Keyword(s):

Ischemic Stroke ◽

Interleukin 6 ◽

Kinase Inhibitor ◽

West African ◽

Cyclin Dependent Kinase ◽

39 In vivo overexpression of the cyclin-dependent kinase inhibitor p21WAF1/C1P1 in cutaneous malignant melanoma

Journal of Dermatological Science ◽

10.1016/0923-1811(96)83606-1 ◽

1996 ◽

Vol 12 (1) ◽

pp. 89

Author(s):

M.J. Trotter ◽

L Tang ◽

V.C. Ho ◽

V.A. Tron

Keyword(s):

Malignant Melanoma ◽

Kinase Inhibitor ◽

Cutaneous Malignant Melanoma ◽

Cyclin Dependent Kinase ◽

Interleukin-6 Induces G1Arrest through Induction of p27Kip1, a Cyclin-Dependent Kinase Inhibitor, and Neuron-like Morphology in LNCaP Prostate Tumor Cells

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1999.0515 ◽

1999 ◽

Vol 257 (2) ◽

pp. 609-614 ◽

Cited By ~ 72

Author(s):

Shunsuke Mori ◽

Kaoru Murakami-Mori ◽

Benjamin Bonavida

Keyword(s):

Tumor Cells ◽

Interleukin 6 ◽

Kinase Inhibitor ◽

Prostate Tumor ◽

Cyclin Dependent Kinase ◽

Prostate Tumor Cells

Hypoxia regulation of the cell cycle in malignant melanoma: putative role for the cyclin-dependent kinase inhibitor p27Kip1

Journal of Cutaneous Pathology ◽

10.1111/j.0303-6987.2004.00205.x ◽

2004 ◽

Vol 31 (7) ◽

pp. 477-482 ◽

Cited By ~ 14

Author(s):

Michael Murphy ◽

J. Andrew Carlson ◽

Martin P. Keough ◽

Kevin P. Claffey ◽

Sabina Signoretti ◽

...

Keyword(s):

Cell Cycle ◽

Malignant Melanoma ◽

Kinase Inhibitor ◽

Cyclin Dependent Kinase ◽

Putative Role

Overexpression of the cyclin-dependent kinase inhibitor p21WAF1/GIP1in human cutaneous malignant melanoma

Journal of Cutaneous Pathology ◽

10.1111/j.1600-0560.1997.tb00790.x ◽

1997 ◽

Vol 24 (5) ◽

pp. 265-271 ◽

Cited By ~ 42

Author(s):

Martin J. Trotter ◽

Liren Tang ◽

Victor A. Tron

Keyword(s):

Malignant Melanoma ◽

Kinase Inhibitor ◽

Cutaneous Malignant Melanoma ◽

Cyclin Dependent Kinase ◽

Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1

Oncogene ◽

10.1038/sj.onc.1202708 ◽

1999 ◽

Vol 18 (25) ◽

pp. 3742-3753 ◽

Cited By ~ 85

Author(s):

Marcin Kortylewski ◽

Peter C Heinrich ◽

Andrzej Mackiewicz ◽

Ute Schniertshauer ◽

Ursula Klingmüller ◽

...

Keyword(s):

Growth Inhibition ◽

Interleukin 6 ◽

Kinase Inhibitor ◽

Melanoma Cells ◽

Oncostatin M ◽

Cyclin Dependent Kinase ◽

P27 Kip1 ◽

A375 Melanoma

Cyclin-dependent kinase inhibitor 2A, isoform 4

Targeted Protein Database ◽

10.2970/tpdb.2007.95 ◽

2007 ◽

Author(s):

Keyword(s):

Kinase Inhibitor ◽

Cyclin Dependent Kinase ◽

Faculty Opinions recommendation of Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1040700.489726 ◽

2006 ◽

Author(s):

Anthony D Ho

Keyword(s):

Stem Cell ◽

Kinase Inhibitor ◽

Cyclin Dependent Kinase ◽

Faculty Opinions recommendation of Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717968027.793467692 ◽

2012 ◽

Author(s):

Michael Sternberg

Keyword(s):

Crystal Structure ◽

Kinase Inhibitor ◽

Cyclin A ◽

Cyclin Dependent Kinase ◽

Cdk2 Complex