Structural and functional characterization of deep-sea thermophilic bacteriophage GVE2 HNH endonuclease

Likui Zhang; Dandan Xu; Yanchao Huang; Xinyuan Zhu; Mianwen Rui; Ting Wan; Xin Zheng; Yulong Shen; Xiangdong Chen; Kesen Ma; Yong Gong

doi:10.1038/srep42542

Structural and functional characterization of deep-sea thermophilic bacteriophage GVE2 HNH endonuclease

Scientific Reports ◽

10.1038/srep42542 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 6

Author(s):

Likui Zhang ◽

Dandan Xu ◽

Yanchao Huang ◽

Xinyuan Zhu ◽

Mianwen Rui ◽

...

Keyword(s):

Deep Sea ◽

Functional Characterization ◽

Thermophilic Bacteriophage

Structural and functional characterization of the deep-sea thermophilic bacteriophage GVE2 tailspike protein

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2020.09.053 ◽

2020 ◽

Vol 164 ◽

pp. 4415-4422

Author(s):

Likui Zhang ◽

Yuhua Yan ◽

Qi Gan ◽

Zhun She ◽

Keli Zhu ◽

...

Keyword(s):

Deep Sea ◽

Functional Characterization ◽

Thermophilic Bacteriophage ◽

Tailspike Protein

Characterization of a novel portal protein from deep-sea thermophilic bacteriophage GVE2

Gene ◽

10.1016/j.gene.2008.05.015 ◽

2008 ◽

Vol 421 (1-2) ◽

pp. 61-66 ◽

Cited By ~ 9

Author(s):

Yiqian Wang ◽

Xiaobo Zhang

Keyword(s):

Deep Sea ◽

Portal Protein ◽

Thermophilic Bacteriophage

Biochemical characterization of a thermostable HNH endonuclease from deep-sea thermophilic bacteriophage GVE2

Applied Microbiology and Biotechnology ◽

10.1007/s00253-016-7568-7 ◽

2016 ◽

Vol 100 (18) ◽

pp. 8003-8012 ◽

Cited By ~ 6

Author(s):

Likui Zhang ◽

Yanchao Huang ◽

Dandan Xu ◽

Lixiang Yang ◽

Kaicheng Qian ◽

...

Keyword(s):

Deep Sea ◽

Biochemical Characterization ◽

Thermophilic Bacteriophage

Molecular and functional characterization of major compatible solute in Deep Sea halophilic actinobacteria of active volcanic Barren Island, Andaman and Nicobar Islands, India

Physiological and Biotechnological Aspects of Extremophiles ◽

10.1016/b978-0-12-818322-9.00019-8 ◽

2020 ◽

pp. 253-267

Author(s):

Balakrishnan Meena ◽

Lawrance Anburajan ◽

Nambali Valsalan Vinithkumar ◽

Ramalingam Kirubagaran ◽

Gopal Dharani

Keyword(s):

Deep Sea ◽

Functional Characterization ◽

Compatible Solute ◽

Andaman And Nicobar Islands ◽

Nicobar Islands ◽

Barren Island ◽

Halophilic Actinobacteria

Characterization of a lysin from deep-sea thermophilic bacteriophage GVE2

Applied Microbiology and Biotechnology ◽

10.1007/s00253-008-1353-1 ◽

2008 ◽

Vol 78 (4) ◽

pp. 635-641 ◽

Cited By ~ 19

Author(s):

Ting Ye ◽

Xiaobo Zhang

Keyword(s):

Deep Sea ◽

Thermophilic Bacteriophage

Morphological and functional characterization of hemocytes from two deep-sea vesicomyid clams Phreagena okutanii and Abyssogena phaseoliformis

Fish & Shellfish Immunology ◽

10.1016/j.fsi.2017.12.058 ◽

2018 ◽

Vol 74 ◽

pp. 281-294 ◽

Cited By ~ 3

Author(s):

Akihiro Tame ◽

Genki Ozawa ◽

Tadashi Maruyama ◽

Takao Yoshida

Keyword(s):

Deep Sea ◽

Functional Characterization

Functional characterization of a major compatible solute in Deep Sea halophilic eubacteria of active volcanic Barren Island, Andaman and Nicobar Islands, India

Infection Genetics and Evolution ◽

10.1016/j.meegid.2019.05.008 ◽

2019 ◽

Vol 73 ◽

pp. 261-265

Author(s):

Lawrance Anburajan ◽

Balakrishnan Meena ◽

Nambali Valsalan Vinithkumar ◽

Ramalingam Kirubagaran ◽

Gopal Dharani

Keyword(s):

Deep Sea ◽

Functional Characterization ◽

Compatible Solute ◽

Andaman And Nicobar Islands ◽

Nicobar Islands ◽

Barren Island

Functional characterization of the GABA transporter GAT-1 from the deep-sea mussel Bathymodiolus septemdierum

Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology ◽

10.1016/j.cbpa.2018.08.016 ◽

2019 ◽

Vol 227 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Azusa Kinjo ◽

Mieko Sassa ◽

Tomoko Koito ◽

Miwa Suzuki ◽

Koji Inoue

Keyword(s):

Deep Sea ◽

Functional Characterization ◽

Gaba Transporter

Identification and characterization of a novel thymidylate synthase from deep-sea thermophilic bacteriophage Geobacillus virus E2

Virus Genes ◽

10.1007/s11262-008-0258-5 ◽

2008 ◽

Vol 37 (2) ◽

pp. 218-224 ◽

Cited By ~ 7

Author(s):

Yiqian Wang ◽

Xiaobo Zhang

Keyword(s):

Thymidylate Synthase ◽

Deep Sea ◽

Thermophilic Bacteriophage ◽

Identification And Characterization

Functional characterization of human brown adipose tissue metabolism

Biochemical Journal ◽

10.1042/bcj20190464 ◽

2020 ◽

Vol 477 (7) ◽

pp. 1261-1286 ◽

Cited By ~ 3

Author(s):

Marie Anne Richard ◽

Hannah Pallubinsky ◽

Denis P. Blondin

Keyword(s):

Adipose Tissue ◽

Brown Adipose Tissue ◽

Functional Characterization ◽

Human Infants ◽

Positron Emission ◽

Brown Adipose ◽

Treatment Of Obesity ◽

And Function

Brown adipose tissue (BAT) has long been described according to its histological features as a multilocular, lipid-containing tissue, light brown in color, that is also responsive to the cold and found especially in hibernating mammals and human infants. Its presence in both hibernators and human infants, combined with its function as a heat-generating organ, raised many questions about its role in humans. Early characterizations of the tissue in humans focused on its progressive atrophy with age and its apparent importance for cold-exposed workers. However, the use of positron emission tomography (PET) with the glucose tracer [18F]fluorodeoxyglucose ([18F]FDG) made it possible to begin characterizing the possible function of BAT in adult humans, and whether it could play a role in the prevention or treatment of obesity and type 2 diabetes (T2D). This review focuses on the in vivo functional characterization of human BAT, the methodological approaches applied to examine these features and addresses critical gaps that remain in moving the field forward. Specifically, we describe the anatomical and biomolecular features of human BAT, the modalities and applications of non-invasive tools such as PET and magnetic resonance imaging coupled with spectroscopy (MRI/MRS) to study BAT morphology and function in vivo, and finally describe the functional characteristics of human BAT that have only been possible through the development and application of such tools.