scholarly journals Serotonin receptor 2A (HTR2A) gene polymorphism predicts treatment response to venlafaxine XR in generalized anxiety disorder

2011 ◽  
Vol 13 (1) ◽  
pp. 21-26 ◽  
Author(s):  
F W Lohoff ◽  
T D Aquino ◽  
S Narasimhan ◽  
P K Multani ◽  
B Etemad ◽  
...  

2019 ◽  
Vol 29 ◽  
pp. S933
Author(s):  
Arun Tiwari ◽  
Clement Zai ◽  
Gwyneth Zai ◽  
Sheraz Cheema ◽  
Nicole Braganza ◽  
...  


Assessment ◽  
2021 ◽  
pp. 107319112110625
Author(s):  
Tom H. Rosenström ◽  
Ville Ritola ◽  
Suoma Saarni ◽  
Grigori Joffe ◽  
Jan-Henry Stenberg

Assessment of treatment response in psychotherapies can be undermined by lack of longitudinal measurement invariance (LMI) in symptom self-report inventories, by measurement error, and/or by wrong model assumptions. To understand and compare these threats to validity of outcome assessment in psychotherapy research, we studied LMI, sum scores, and Davidian Curve Item Response Theory models in a naturalistic guided internet psychotherapy treatment register of 2,218 generalized anxiety disorder (GAD) patients and 3,922 depressive disorder (DD) patients (aged ≥16 years). Symptoms were repeatedly assessed by Generalized Anxiety Disorder Assessment-7 (GAD-7) or Beck Depression Inventory. The symptom self-reports adhered to LMI under equivalence testing, suggesting sum scores are reasonable proxies for disorder status. However, the standard LMI assumption of normally distributed latent factors did not hold and inflated treatment response estimates by 0.2 to 0.3 standard deviation units compared with sum scores. Further methodological research on non-normally distributed latent constructs holds promise in advancing LMI and mental health assessment.



2019 ◽  
Vol 259 ◽  
pp. 56-66 ◽  
Author(s):  
Yi-huan Chen ◽  
Jie Bai ◽  
Di Wu ◽  
Shou-fen Yu ◽  
Xiao-ling Qiang ◽  
...  




2009 ◽  
Vol 166 (3) ◽  
pp. 302-310 ◽  
Author(s):  
Jack B. Nitschke ◽  
Issidoros Sarinopoulos ◽  
Desmond J. Oathes ◽  
Tom Johnstone ◽  
Paul J. Whalen ◽  
...  


2005 ◽  
Vol 52 (3) ◽  
pp. 155-162 ◽  
Author(s):  
Myoung-Jin Choi ◽  
Rhee-Hun Kang ◽  
Byung-Joo Ham ◽  
Han-Yong Jeong ◽  
Min-Soo Lee


2015 ◽  
Vol 30 (5) ◽  
pp. 265-271 ◽  
Author(s):  
José M. Olivares ◽  
Enrique Álvarez ◽  
José L. Carrasco ◽  
María Pérez Páramo ◽  
Vanessa López-Gómez


Sign in / Sign up

Export Citation Format

Share Document