Practical asymmetric synthesis of β-hydroxy-β-trifluoromethylated ketones via the first example of the in situ generation of trifluoro-acetaldehyde and its successive asymmetric carbon–carbon bond formation reaction with chiral imines

Chemical Communications ◽

10.1039/b408226e ◽

2004 ◽

pp. 2056-2057 ◽

Author(s):

Kazumasa Funabiki ◽

Wataru Hashimoto ◽

Masaki Matsui

Keyword(s):

Asymmetric Synthesis ◽

Bond Formation ◽

Formation Reaction ◽

Carbon Bond ◽

Carbon Carbon Bond ◽

In Situ Generation ◽

Chiral Imines ◽

Asymmetric Carbon

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Practical Asymmetric Synthesis of ?-Hydroxy-?-trifluoromethylated Ketones via the First Example of the in situ Generation of Trifluoroacetaldehyde and Its Successive Asymmetric Carbon?Carbon Bond Formation Reaction with Chiral Imines.

10.1002/chin.200510024 ◽

2005 ◽

Vol 36 (10) ◽

Author(s):

Kazumasa Funabiki ◽

Wataru Hashimoto ◽

Masaki Matsui

Keyword(s):

Asymmetric Synthesis ◽

Bond Formation ◽

Formation Reaction ◽

Carbon Bond ◽

Carbon Carbon Bond ◽

In Situ Generation ◽

Chiral Imines ◽

Asymmetric Carbon

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Asymmetric synthesis of β-hydroxy-β-trifluoromethylated ketones via in situ generation of trifluoroacetaldehyde and its asymmetric carbon–carbon bond formation reaction with chiral imines in aqueous media

Journal of Fluorine Chemistry ◽

10.1016/j.jfluchem.2005.12.020 ◽

2006 ◽

Vol 127 (4-5) ◽

pp. 545-547 ◽

Author(s):

Kazumasa Funabiki ◽

Kazutoshi Hasegawa ◽

Yoshihiro Murase ◽

Hideyuki Nagaya ◽

Masaki Matsui

Keyword(s):

Asymmetric Synthesis ◽

Bond Formation ◽

Aqueous Media ◽

Formation Reaction ◽

Carbon Bond ◽

Carbon Carbon Bond ◽

In Situ Generation ◽

Chiral Imines ◽

Asymmetric Carbon

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Asymmetric Synthesis of β-Hydroxy-β-trifluoromethylated Ketones via in situ Generation of Trifluoroacetaldehyde and Its Asymmetric Carbon—Carbon Bond Formation Reaction with Chiral Imines in Aqueous Media.

10.1002/chin.200638084 ◽

2006 ◽

Vol 37 (38) ◽

Author(s):

Kazumasa Funabiki ◽

Kazutoshi Hasegawa ◽

Yoshihiro Murase ◽

Hideyuki Nagaya ◽

Masaki Matsui

Keyword(s):

Asymmetric Synthesis ◽

Bond Formation ◽

Aqueous Media ◽

Formation Reaction ◽

Carbon Bond ◽

Carbon Carbon Bond ◽

In Situ Generation ◽

Chiral Imines ◽

Asymmetric Carbon

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First Catalytic Asymmetric Synthesis of ?-Amino-?-polyfluoroalkyl Ketones via Proline-Catalyzed Direct Asymmetric Carbon?Carbon Bond Formation Reaction of Polyfluoroalkylated Aldimines.

10.1002/chin.200505069 ◽

2005 ◽

Vol 36 (5) ◽

Author(s):

Kazumasa Funabiki ◽

Masashi Nagamori ◽

Sakiko Goushi ◽

Masaki Matsui

Keyword(s):

Asymmetric Synthesis ◽

Bond Formation ◽

Formation Reaction ◽

Carbon Bond ◽

Catalytic Asymmetric Synthesis ◽

Carbon Carbon Bond ◽

Catalytic Asymmetric ◽

Asymmetric Carbon

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First catalytic asymmetric synthesis of β-amino-β-polyfluoroalkyl ketones via proline-catalysed direct asymmetric carbon–carbon bond formation reaction of polyfluoroalkylated aldimines

Chemical Communications ◽

10.1039/b406000h ◽

2004 ◽

pp. 1928-1929 ◽

Author(s):

Kazumasa Funabiki ◽

Masashi Nagamori ◽

Sakiko Goushi ◽

Masaki Matsui

Keyword(s):

Asymmetric Synthesis ◽

Bond Formation ◽

Formation Reaction ◽

Carbon Bond ◽

Catalytic Asymmetric Synthesis ◽

Carbon Carbon Bond ◽

Catalytic Asymmetric ◽

Asymmetric Carbon

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Catalytic asymmetric carbon-carbon bond formation: asymmetric synthesis of cis-decalin derivatives by palladium-catalyzed cyclization of prochiral alkenyl iodides

The Journal of Organic Chemistry ◽

10.1021/jo00281a007 ◽

1989 ◽

Vol 54 (20) ◽

pp. 4738-4739 ◽

Author(s):

Yoshihiro Sato ◽

Mikiko Sodeoka ◽

Masakatsu Shibasaki

Keyword(s):

Asymmetric Synthesis ◽

Bond Formation ◽

Carbon Bond ◽

Carbon Carbon Bond ◽

Palladium Catalyzed ◽

Catalytic Asymmetric ◽

Asymmetric Carbon

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Asymmetric carbon-carbon bond formation using optically active (.eta.-C5H5)Fe(CO)2-vinyl ether complexes. Asymmetric control at two adjacent carbon centers

Organometallics ◽

10.1021/om00136a042 ◽

1986 ◽

Vol 5 (5) ◽

pp. 1062-1063 ◽

Author(s):

Myron. Rosenblum ◽

Mark M. Turnbull ◽

Bruce M. Foxman

Keyword(s):

Vinyl Ether ◽

Bond Formation ◽

Optically Active ◽

Carbon Bond ◽

Carbon Centers ◽

Carbon Carbon Bond ◽

Asymmetric Carbon

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ChemInform Abstract: Novel Carbon-Carbon Bond Formation Reaction of Methoxyallene Oxide Promoted by TiI4.

10.1002/chin.200114081 ◽

2001 ◽

Vol 32 (14) ◽

pp. no-no

Author(s):

Ryuuichirou Hayakawa ◽

Makoto Shimizu

Keyword(s):

Bond Formation ◽

Formation Reaction ◽

Carbon Bond ◽

Carbon Carbon Bond

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Novel carbon-carbon bond formation reaction at the C-4 position of an azetidin-2-one by means of radical cyclization

The Journal of Organic Chemistry ◽

10.1021/jo00247a005 ◽

1988 ◽

Vol 53 (12) ◽

pp. 2683-2687 ◽

Author(s):

Tetsuji Kametani ◽

Shih Der Chu ◽

Akira Itoh ◽

Sayuri Maeda ◽

Toshio Honda

Keyword(s):

Bond Formation ◽

Radical Cyclization ◽

Formation Reaction ◽

Carbon Bond ◽

Carbon Carbon Bond

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Hydrolase-catalyzed asymmetric carbon–carbon bond formation in organic synthesis

RSC Advances ◽

10.1039/c4ra11462k ◽

2015 ◽

Vol 5 (22) ◽

pp. 16801-16814 ◽

Author(s):

Zhi Guan ◽

Ling-Yu Li ◽

Yan-Hong He

Keyword(s):

Organic Synthesis ◽

Bond Formation ◽

Carbon Bond ◽

Bond Forming ◽

Carbon Carbon Bond ◽

Bond Forming Reactions ◽

Asymmetric Carbon

This article reviews the hydrolase-catalyzed asymmetric carbon–carbon bond-forming reactions for the preparation of enantiomerically enriched compounds in organic synthesis.

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