Nanostructured solid substrates for efficient laser desorption/ionization mass spectrometry (LDI-MS) of low molecular weight compounds

The Analyst ◽  
2013 ◽  
Vol 138 (23) ◽  
pp. 7053 ◽  
Author(s):  
Yuliya E. Silina ◽  
Dietrich A. Volmer
Keyword(s):  
Mass Spectrometry ◽  
Molecular Weight ◽  
Laser Desorption ◽  
Ionization Mass Spectrometry ◽  
Low Molecular Weight ◽  
Ionization Mass ◽  
Laser Desorption Ionization ◽  
Desorption Ionization ◽  
Solid Substrates ◽  
Low Molecular Weight Compounds

scholarly journals Ammonium Ion Exchanged Zeolite for Laser Desorption/Ionization Mass Spectrometry of Phosphorylated Peptides

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Mengrui Yang ◽  
Tatsuya Fujino
Keyword(s):  
Mass Spectrometry ◽  
Molecular Weight ◽  
Laser Desorption ◽  
Ionization Mass Spectrometry ◽  
Ammonium Ion ◽  
Low Molecular Weight ◽  
Ionization Mass ◽  
Laser Desorption Ionization ◽  
Desorption Ionization ◽  
Phosphorylated Peptides

α-Cyano-4-hydroxycinnamic acid (CHCA), an organic matrix molecule for matrix-assisted laser desorption/ionization mass spectrometry, was adsorbed toNH4+-type zeolite surface, and this new matrix was used for the detection of low-molecular-weight compounds. It was found that this matrix could simplify the mass spectrum in the low-molecular-weight region and prevent interference from fragments and alkali metal ion adducted species. CHCA adsorbed toNH4+-type ZSM5 zeolite (CHCA/NH4ZSM5) was used to measure atropine and aconitine, two toxic alkaloids in plants. In addition, CHCA/NH4ZSM5 enabled us to detect phosphorylated peptides; peaks of the protonated peptides had higher intensities than the peaks observed using CHCA only.

A novel trityl/acridine derivatization agent for analysis of thiols by (matrix-assisted)(nanowire-assisted)laser desorption/ionization and electrospray ionization mass spectrometry

2017 ◽  
Vol 9 (45) ◽  
pp. 6335-6340 ◽  
Author(s):  
Artyom P. Topolyan ◽  
Maria A. Belyaeva ◽  
Mariya S. Slyundina ◽  
Valentina V. Ilyushenkova ◽  
Andrey A. Formanovsky ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Molecular Weight ◽  
Electrospray Ionization ◽  
Electrospray Ionization Mass Spectrometry ◽  
Laser Desorption ◽  
Fixed Charge ◽  
Low Molecular Weight ◽  
Ionization Mass ◽  
Laser Desorption Ionization ◽  
Desorption Ionization

A new agent was used for fixed-charge derivatization of low molecular weight thiols.

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