Enhanced propionic acid production from whey lactose with immobilized Propionibacterium acidipropionici and the role of trehalose synthesis in acid tolerance

2015 ◽  
Vol 17 (1) ◽  
pp. 250-259 ◽  
Author(s):  
Ling Jiang ◽  
Huaiyan Cui ◽  
Liying Zhu ◽  
Yi Hu ◽  
Xian Xu ◽  
...  
Keyword(s):  
Propionic Acid ◽  
Acid Production ◽  
Batch Fermentation ◽  
Acid Tolerance ◽  
Fed Batch ◽  
Propionibacterium Acidipropionici ◽  
Fed Batch Fermentation ◽  
Propionic Acid Production ◽  
Trehalose Synthesis

High propionic acid production could be achieved with an enhanced trehalose synthesis mutant immobilized on PEI-Poraver in FBB fed-batch fermentation.

Efficient Production of Propionic Acid in the Fed-Batch Fermentation of Propionibacterium acidipropionici and Its Metabolic Flux Analysis

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Zhang Y ◽  
◽  
Zhang K ◽  
Li X ◽  
Wang Z ◽  
...  
Keyword(s):  
Propionic Acid ◽  
Batch Fermentation ◽  
Metabolic Flux ◽  
Flux Distribution ◽  
Efficient Production ◽  
Flux Analysis ◽  
Fed Batch ◽  
Propionibacterium Acidipropionici ◽  
Metabolic Flux Distribution ◽  
Fed Batch Fermentation

To improve the fermentation efficiency of Propionibacterium acidipropionici, a simplified metabolic network was established to provide theoretical guidance for medium optimization and process regulation. The effect of glucose and glycerol on propionic acid production and metabolic flux distribution was investigated and the combination of glucose and glycerol was optimized. The results showed that the productivity of propionic acid could be improved by enhancing the synthesis of pyruvate and its flux distribution to the oxaloacetate branch. Finally, the scaled-up fed-batch fermentation of P. acidipropionici was conducted. The concentration of propionic acid reached 51.75 ± 3.62g/L with a glucose/glycerol ratio of 4:1, an improvement of 79.25% relative to the use of glucose alone, and the corresponding productivity and yield were 0.39g/(L· h) and 0.52g/g, respectively. Therefore, the combination of glucose and glycerol significantly improved the productivity of propionic acid and provides a new strategy for industrial production.

Batch Fermentation Model of Propionic Acid Production by Propionibacterium acidipropionici in Different Carbon Sources

2008 ◽  
Vol 151 (2-3) ◽  
pp. 333-341 ◽  
Author(s):  
Jefferson Coral ◽  
Susan Grace Karp ◽  
Luciana Porto de Souza Vandenberghe ◽  
José Luis Parada ◽  
Ashok Pandey ◽  
...  
Keyword(s):  
Propionic Acid ◽  
Acid Production ◽  
Batch Fermentation ◽  
Carbon Sources ◽  
Propionibacterium Acidipropionici ◽  
Fermentation Model ◽  
Propionic Acid Production

Phenyllactic acid production by fed-batch fermentation of Lactobacillus plantarum CECT-221

2010 ◽  
Vol 150 ◽  
pp. 320-320 ◽  
Author(s):  
Noelia Rodríguez ◽  
Jose Manuel Salgado ◽  
Belén Max ◽  
Sandra Cortés ◽  
Jose Manuel Domínguez
Keyword(s):  
Lactobacillus Plantarum ◽  
Acid Production ◽  
Batch Fermentation ◽  
Fed Batch ◽  
Phenyllactic Acid ◽  
Fed Batch Fermentation

scholarly journals Propionic acid production from corn stover hydrolysate by Propionibacterium acidipropionici

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Xiaoqing Wang ◽  
Davinia Salvachúa ◽  
Violeta Sànchez i Nogué ◽  
William E. Michener ◽  
Adam D. Bratis ◽  
...  
Keyword(s):  
Corn Stover ◽  
Propionic Acid ◽  
Acid Production ◽  
Propionibacterium Acidipropionici ◽  
Propionic Acid Production ◽  
Corn Stover Hydrolysate

Efficient acetic acid production by repeated fed-batch fermentation using two fermentors

1991 ◽  
Vol 36 (3) ◽  
Author(s):  
Takaomi Ito ◽  
Hiroyuki Sota ◽  
Hiroyuki Honda ◽  
Kazuyuki Shimizu ◽  
Takeshi Kobayashi
Keyword(s):  
Acetic Acid ◽  
Acid Production ◽  
Batch Fermentation ◽  
Fed Batch ◽  
Acetic Acid Production ◽  
Fed Batch Fermentation
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