Enantioselective cascade double Michael addition of 3-nitro-2H-chromenes and acyclic enones: efficient synthesis of functionalized tricyclic chroman derivatives

Jun-Hua Li; Da-Ming Du

doi:10.1039/c5ob01211b

Enantioselective cascade double Michael addition of 3-nitro-2H-chromenes and acyclic enones: efficient synthesis of functionalized tricyclic chroman derivatives

Organic & Biomolecular Chemistry ◽

10.1039/c5ob01211b ◽

2015 ◽

Vol 13 (37) ◽

pp. 9600-9609 ◽

Cited By ~ 9

Author(s):

Jun-Hua Li ◽

Da-Ming Du

Keyword(s):

Michael Addition ◽

Primary Amine ◽

Efficient Synthesis ◽

Unsaturated Ketones

An efficient protocol for the construction of enantiomerically enriched tetrahydro-6H-benzo[c]chromenes by the cascade double Michael addition of 3-nitro-2H-chromenes and α,β-unsaturated ketones catalyzed by a quinine-derived primary amine has been developed.

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ChemInform Abstract: Highly Effective and Enantioselective Michael Addition of 4-Hydroxycoumarin to α,β-Unsaturated Ketones Promoted by Simple Chiral Primary Amine Thiourea Bifunctional Catalysts.

ChemInform ◽

10.1002/chin.201128136 ◽

2011 ◽

Vol 42 (28) ◽

pp. no-no

Author(s):

Ren-Qiang Mei ◽

Xiao-Ying Xu ◽

Yan-Chun Li ◽

Ji-Ya Fu ◽

Qing-Chun Huang ◽

...

Keyword(s):

Michael Addition ◽

Primary Amine ◽

Bifunctional Catalysts ◽

Unsaturated Ketones ◽

Highly Effective

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Highly effective and enantioselective Michael addition of 4-hydroxycoumarin to α,β-unsaturated ketones promoted by simple chiral primary amine thiourea bifunctional catalysts

Tetrahedron Letters ◽

10.1016/j.tetlet.2011.01.054 ◽

2011 ◽

Vol 52 (14) ◽

pp. 1566-1568 ◽

Cited By ~ 37

Author(s):

Ren-Qiang Mei ◽

Xiao-Ying Xu ◽

Yan-Chun Li ◽

Ji-Ya Fu ◽

Qing-Chun Huang ◽

...

Keyword(s):

Michael Addition ◽

Primary Amine ◽

Bifunctional Catalysts ◽

Unsaturated Ketones ◽

Highly Effective

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Organocatalytic Michael Addition of Naphthoquinone with α,β-Unsaturated Ketones: Primary Amine Catalyzed Asymmetric Synthesis of Lapachol Analogues

European Journal of Organic Chemistry ◽

10.1002/ejoc.201001570 ◽

2011 ◽

Vol 2011 (11) ◽

pp. 2142-2147 ◽

Cited By ~ 18

Author(s):

Guangcun Zhang ◽

Yifeng Wang ◽

Wei Zhang ◽

Xiangsheng Xu ◽

Aiguo Zhong ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Michael Addition ◽

Primary Amine ◽

Unsaturated Ketones

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Efficient Synthesis of Substituted 3-Amino-3,4-dihydropyran-2-ones Diastereo and Enantioselective Tandem Michael Addition and Lactonization between α,β-Unsaturated Ketones and Glycine-Derived Silyl Enolates Using a Chiral Quaternary Ammonium Phenoxide

Heterocycles ◽

10.3987/com-06-s(k)48 ◽

2007 ◽

Vol 72 (1) ◽

pp. 553 ◽

Cited By ~ 8

Author(s):

Teruaki Mukaiyama ◽

Hitoshi Nagao ◽

Yoshinobu Yamane

Keyword(s):

Michael Addition ◽

Quaternary Ammonium ◽

Efficient Synthesis ◽

Unsaturated Ketones

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Efficient Synthesis of Substituted 3-Amino-3,4-dihydropyran-2-ones. Diastereo- and Enantioselective Tandem Michael Addition and Lactonization Between α,β-Unsaturated Ketones and Glycine-Derived Silyl Enolates Using a Chiral Quaternary Ammonium Phenoxide.

ChemInform ◽

10.1002/chin.200738132 ◽

2007 ◽

Vol 38 (38) ◽

Author(s):

Hitoshi Nagao ◽

Yoshinobu Yamane ◽

Teruaki Mukaiyama

Keyword(s):

Michael Addition ◽

Quaternary Ammonium ◽

Efficient Synthesis ◽

Unsaturated Ketones

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ChemInform Abstract: Organocatalytic Michael Addition of Naphthoquinone with α,β-Unsaturated Ketones: Primary Amine Catalyzed Asymmetric Synthesis of Lapachol Analogues.

ChemInform ◽

10.1002/chin.201130089 ◽

2011 ◽

Vol 42 (30) ◽

pp. no-no

Author(s):

Guangcun Zhang ◽

Yifeng Wang ◽

Wei Zhang ◽

Xiangsheng Xu ◽

Aiguo Zhong ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Michael Addition ◽

Primary Amine ◽

Unsaturated Ketones

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Palladium-Catalyzed Three-Component Coupling Reaction of Benzyl Chlorides, Allyltributylstannane, and Carbon Monoxide: Efficient Synthesis of α,β-Unsaturated Ketones

CHINESE JOURNAL OF CATALYSIS (CHINESE VERSION) ◽

10.3724/sp.j.1088.2012.10930 ◽

2013 ◽

Vol 33 (3) ◽

pp. 523-529

Author(s):

Xin ZHANG ◽

Xiujuan FENG ◽

Hesong LIU ◽

Yuhu QIN ◽

Yao DAI

Keyword(s):

Carbon Monoxide ◽

Coupling Reaction ◽

Efficient Synthesis ◽

Unsaturated Ketones ◽

Benzyl Chlorides ◽

Palladium Catalyzed ◽

Three Component Coupling

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ChemInform Abstract: Efficient Synthesis of 1-Amino-2-naphthalenecarboxylic Acid Derivatives via a Sequential Michael Addition/Enolate-Nitrile Coupling Route and Its Application to Facile Preparation of 9-Amino Analogues of Arylnaphthofuranone Lignans.

ChemInform ◽

10.1002/chin.199725090 ◽

2010 ◽

Vol 28 (25) ◽

pp. no-no

Author(s):

K. KOBAYASHI ◽

T. UNEDA ◽

K. TAKADA ◽

H. TANAKA ◽

T. KITAMURA ◽

...

Keyword(s):

Michael Addition ◽

Efficient Synthesis ◽

Facile Preparation

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Asymmetric Sulfa-Michael Addition to α-Substituted Vinyl Ketones Catalyzed by Chiral Primary Amine

Organic Letters ◽

10.1021/ol5022178 ◽

2014 ◽

Vol 16 (17) ◽

pp. 4626-4629 ◽

Cited By ~ 34

Author(s):

Niankai Fu ◽

Long Zhang ◽

Sanzhong Luo ◽

Jin-Pei Cheng

Keyword(s):

Michael Addition ◽

Primary Amine

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Highly enantioselective aza-Michael addition reactions of 4-nitrophthalimide with α,β-unsaturated ketones

RSC Advances ◽

10.1039/c3ra41179f ◽

2013 ◽

Vol 3 (29) ◽

pp. 11498 ◽

Cited By ~ 7

Author(s):

Shijun Ma ◽

Lulu Wu ◽

Ming Liu ◽

Xiufang Xu ◽

Yaodong Huang ◽

...

Keyword(s):

Michael Addition ◽

Addition Reactions ◽

Unsaturated Ketones

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