Palladium-catalyzed domino Heck/intermolecular cross-coupling: efficient synthesis of 4-alkylated isoquinoline derivatives

2017 ◽  
Vol 53 (15) ◽  
pp. 2386-2389 ◽  
Author(s):  
Tuanli Yao ◽  
Tao Liu ◽  
Changhui Zhang

The first example of a σ-alkylpalladium(ii) intermediate promoting cyclization of alkynes containing a proximate nucleophilic center is presented.

2017 ◽  
Vol 41 (8) ◽  
pp. 3172-3176 ◽  
Author(s):  
Zhihao Liu ◽  
Wei Wei ◽  
Lu Xiong ◽  
Qiang Feng ◽  
Yaojie Shi ◽  
...  

A versatile method of palladium catalyzed cross-coupling between pinacol vinylboronate and (het)arylbromides to obtain trans-(het)arylvinylboronates in excellent yields and selectivity.


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