Palladium-catalyzed dehydrogenation of dihydro-heterocycles using isoprene as the hydrogen acceptor without oxidants

2017 ◽  
Vol 7 (3) ◽  
pp. 565-569 ◽  
Author(s):  
Xiao-Jun Liu ◽  
Wen-Peng Wang ◽  
Cong-De Huo ◽  
Xi-Cun Wang ◽  
Zheng-Jun Quan
Keyword(s):  
Hydrogen Acceptor ◽  
Palladium Catalyzed ◽  
General Method ◽  
Heteroatom Compounds

An efficient and general method for Pd-catalyzed dehydrogenative aromatization of dihydro-heteroatom compounds without external O2 and H2 is first described.

Sequential C-Selective Difluoromethylation/Pd-Catalyzed Decarboxylative Protonation: An Efficient Access to Tertiary Difluoromethylated Scaffolds

2019 ◽  
Author(s):  
Nicolas Duchemin ◽  
Roberto Buccafusca ◽  
Marc Daumas ◽  
Vincent Ferey ◽  
Stellios Arseniyadis
Keyword(s):  
Drug Development ◽  
Late Stage ◽  
Efficient Access ◽  
Palladium Catalyzed ◽  
General Method

We report here a general method that allows a highly straightforward access to tertiary difluoromethylated compounds. The strategy relies on a two-step sequence featuring a C-selective electrophilic difluoromethylation and an unprecedented palladium-catalyzed decarboxylative protonation. Considering the generality of the method and the attractive properties offered by the difluoromethyl group, this approach provides a valuable tool for late-stage functionalization and drug development.<br>

ChemInform Abstract: General Method for the Preparation of Active Esters by Palladium-Catalyzed Alkoxycarbonylation of Aryl Bromides.

ChemInform ◽  
2015 ◽  
Vol 46 (26) ◽  
pp. no-no
Author(s):  
Angelina M. de Almeida ◽  
Thomas L. Andersen ◽  
Anders T. Lindhardt ◽  
Mauro V. de Almeida ◽  
Troels Skrydstrup
Keyword(s):  
Active Esters ◽  
Aryl Bromides ◽  
Palladium Catalyzed ◽  
General Method

A General Method for Palladium-Catalyzed Reactions of Primary Sulfonamides with Aryl Nonaflates

2011 ◽  
Vol 76 (11) ◽  
pp. 4552-4563 ◽  
Author(s):  
Shashank Shekhar ◽  
Travis B. Dunn ◽  
Brian J. Kotecki ◽  
Donna K. Montavon ◽  
Steven C. Cullen
Keyword(s):  
Palladium Catalyzed ◽  
Catalyzed Reactions ◽  
General Method

An improved general method for palladium catalyzed alkenylations and alkynylations of aryl halides under microwave conditions

2007 ◽  
Vol 48 (28) ◽  
pp. 4801-4803 ◽  
Author(s):  
Andrea Togninelli ◽  
Harsukh Gevariya ◽  
Maddalena Alongi ◽  
Maurizio Botta
Keyword(s):  
Aryl Halides ◽  
Palladium Catalyzed ◽  
General Method

Oxidant- and hydrogen acceptor-free palladium catalyzed dehydrogenative cyclization of acylhydrazones to substituted oxadiazoles

2018 ◽  
Vol 5 (3) ◽  
pp. 386-390 ◽  
Author(s):  
Qiangqiang Jiang ◽  
Xinghui Qi ◽  
Chenyang Zhang ◽  
Xuan Ji ◽  
Jin Li ◽  
...  
Keyword(s):  
Efficient Method ◽  
Hydrogen Acceptor ◽  
Palladium Catalyzed

An efficient method for the synthesis of 2,5-disubstituted 1,3,4-oxadiazoles has been developed through palladium(0) catalyzed dehydrogenative cyclization ofN-arylidenearoylhydrazides without oxidants and hydrogen acceptors.

An Improved General Method for Palladium-Catalyzed Alkenylations and Alkynylations of Aryl Halides under Microwave Conditions.

ChemInform ◽  
2007 ◽  
Vol 38 (42) ◽  
Author(s):  
Andrea Togninelli ◽  
Harsukh Gevariya ◽  
Maddalena Alongi ◽  
Maurizio Botta
Keyword(s):  
Aryl Halides ◽  
Palladium Catalyzed ◽  
General Method
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