AB3-loaded and tumor-targeted unimolecular micelles for medullary thyroid cancer treatment

Multifunctional unimolecular micelles conjugated with KE108, a superior MTC-targeting ligand, were developed for targeted delivery of AB3 to treat MTC.

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A new therapeutic approach in medullary thyroid cancer treatment: Inhibition of oncogenic RET signaling by adenoviral vector-mediated expression of a dominant-negative RET mutant

Surgery ◽

10.1067/msy.2002.128560 ◽

2002 ◽

Vol 132 (6) ◽

pp. 991-997 ◽

Cited By ~ 24

Author(s):

Matthias Drosten ◽

Andreja Frilling ◽

Thorsten Stiewe ◽

Brigitte M. Pützer

Keyword(s):

Thyroid Cancer ◽

Cancer Treatment ◽

Therapeutic Approach ◽

Adenoviral Vector ◽

Medullary Thyroid Cancer ◽

Dominant Negative ◽

Medullary Thyroid

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Inhibition of oncogenic RET signaling by Ad vector-mediated expression of a dominant-negative RET-mutant: implications for medullary thyroid cancer treatment

European Journal of Cancer ◽

10.1016/s0959-8049(02)81142-x ◽

2002 ◽

Vol 38 ◽

pp. S146

Keyword(s):

Thyroid Cancer ◽

Cancer Treatment ◽

Medullary Thyroid Cancer ◽

Dominant Negative ◽

Medullary Thyroid

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Incidentally Found Medullary Thyroid Cancer: Treatment Rationale for Small Tumors

World Journal of Surgery ◽

10.1007/s00268-003-7121-6 ◽

2004 ◽

Vol 28 (4) ◽

pp. 397-401 ◽

Cited By ~ 21

Author(s):

Andreas Raffel ◽

Kenko Cupisti ◽

Markus Krausch ◽

Achim Wolf ◽

Klaus-Martin Schulte ◽

...

Keyword(s):

Thyroid Cancer ◽

Cancer Treatment ◽

Medullary Thyroid Cancer ◽

Medullary Thyroid

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Incidentally found medullary thyroid cancer: treatment rationale for small tumors

European Surgery ◽

10.1007/s10353-004-0086-3 ◽

2004 ◽

Vol 36 (4) ◽

pp. 264-265

Author(s):

C. Scheuba

Keyword(s):

Thyroid Cancer ◽

Cancer Treatment ◽

Medullary Thyroid Cancer ◽

Medullary Thyroid

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59. A Novel Therapeutic Strategy in Medullary Thyroid Cancer Treatment: Inhibition of Oncogenic RET Signalling by a Dominant-Negative RET-Mutant

Molecular Therapy ◽

10.1016/s1525-0016(16)42889-3 ◽

2002 ◽

Vol 5 (5) ◽

pp. S21-S22

Keyword(s):

Thyroid Cancer ◽

Cancer Treatment ◽

Therapeutic Strategy ◽

Medullary Thyroid Cancer ◽

Dominant Negative ◽

Medullary Thyroid ◽

Novel Therapeutic

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Abstract #1101 The Value of Calcitonin Calcium Stimulation Test Levels as Predictors of Medullary Thyroid Cancer.

Endocrine Practice ◽

10.1016/s1530-891x(20)47466-x ◽

2018 ◽

Vol 24 ◽

pp. 273-274

Author(s):

Corin Badiu ◽

Mara Baet ◽

Ruxandra Dobrescu ◽

Andra Caragheorgheopol ◽

Corneci Cristina

Keyword(s):

Thyroid Cancer ◽

Medullary Thyroid Cancer ◽

Stimulation Test ◽

Medullary Thyroid ◽

Calcium Stimulation

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Intraoperative and postoperative care of unsuspected pheochromocytoma in medullary thyroid cancer

Otolaryngology ◽

10.1016/s0194-5998(94)70538-0 ◽

1994 ◽

Vol 111 (5) ◽

pp. 665-668

Author(s):

S YEE ◽

S STERN

Keyword(s):

Thyroid Cancer ◽

Postoperative Care ◽

Medullary Thyroid Cancer ◽

Medullary Thyroid

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Immunoscintigraphy in Medullary Thyroid Cancer Using an 123I- or 111ln-Labelled Monoclonal Anti-CEA Antibody Fragment

Nuklearmedizin ◽

10.1055/s-0038-1624348 ◽

1986 ◽

Vol 25 (06) ◽

pp. 227-231 ◽

Cited By ~ 6

Author(s):

Chr. Eilles ◽

W. Spiegel ◽

W. Becker ◽

W. Börner ◽

Chr. Reiners

Keyword(s):

Bone Marrow ◽

Thyroid Cancer ◽

Potassium Iodide ◽

Medullary Thyroid Cancer ◽

Elevated Serum ◽

Antibody Fragment ◽

Special Importance ◽

Medullary Thyroid ◽

Medullary Cancer ◽

Serum Cea

The monoclonal anti-CEA F(ab’)2 fragment MAb BW 431/31, labelled with 123I or111 In, was used for immunoscintigraphy (IS) in 9 patients with medullary cancer of the thyroid (CCC). The results of 11 studies lead to the following conclusions: 1) When using radioiodine as a label for MAb in IS, potassium iodide is absolutely necessary to block the thyroid which is of special importance in patients with thyroid cancer; 2) Preinjection of “cold” MAb reduces the relatively high unspecific uptake (especially in bone marrow) of MAb BW 431/31, which is of special importance for the antibody labelled with 111 In; 3) IS with MAb BW 413/31 in patients with CCC and elevated serum CEA is positive only in cases with large secondaries; and 4) In patients with CCC and several manifestations of secondaries, only a single (large) metastasis may be apparent.

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