A fast-response two-photon fluorescent probe for the detection of Cys over GSH/Hcy with a large turn-on signal and its application in living tissues

2017 ◽  
Vol 5 (1) ◽  
pp. 134-138 ◽  
Author(s):  
Jian-Yong Wang ◽  
Zhan-Rong Liu ◽  
Mingguang Ren ◽  
Xiuqi Kong ◽  
Weiying Lin

We developed a novel two-photon fluorescent probe for sensing Cys specifically. The two-photon fluorescent probe exhibited favorable properties and was successfully applied for imaging Cys in living cells and tissues.

2015 ◽  
Vol 51 (26) ◽  
pp. 5754-5757 ◽  
Author(s):  
Kaibo Zheng ◽  
Weiying Lin ◽  
Dan Cheng ◽  
Hua Chen ◽  
Yong Liu ◽  
...  

The first two-photon fluorescent probe for specific detection of nitroxyl is designed and synthesized, and we have further demonstrated that the new two-photon fluorescent probe could be employed to image nitroxyl in living cells and tissues.


2018 ◽  
Vol 10 (22) ◽  
pp. 2546-2550 ◽  
Author(s):  
Kai Zhou ◽  
Mingguang Ren ◽  
Li Wang ◽  
Zihong Li ◽  
Weiying Lin

We have developed a new two-photon fluorescent HOCl probe (TP-HA). Fluorescence imaging shows that TP-HA is suitable for visualization of the changes of HOCl in living cells and tissues.


2015 ◽  
Vol 7 (6) ◽  
pp. 2386-2390 ◽  
Author(s):  
Tun Tang ◽  
Yimin Zhou ◽  
Yuqi Chen ◽  
Mengjun Li ◽  
Yan Feng ◽  
...  

A novel two-photon fluorescent “turn-on” probe could detect methylglyoxal levels in living cells conveniently.


The Analyst ◽  
2018 ◽  
Vol 143 (23) ◽  
pp. 5799-5804 ◽  
Author(s):  
Wan Sun ◽  
Jing-Xue Cui ◽  
Le-Le Ma ◽  
Zhong-Lin Lu ◽  
Bing Gong ◽  
...  

TP-2Bz, as a nucleus targeting “D–π–A” molecule, was developed as a two-photon turn-on fluorescent probe for the viscosity and GQ DNA detection in cell nuclei.


2019 ◽  
Vol 284 ◽  
pp. 744-750 ◽  
Author(s):  
Carlos Benitez-Martin ◽  
Juan A. Guadix ◽  
John R. Pearson ◽  
Francisco Najera ◽  
Jose M. Perez-Pomares ◽  
...  

2018 ◽  
Vol 42 (17) ◽  
pp. 14075-14078 ◽  
Author(s):  
Shiying Gao ◽  
Yonghe Tang ◽  
Weiying Lin

A two-photon fluorescent probe Co-Cys for detecting cysteine has been designed to monitor cysteine in cells, tissues and zebrafish.


2019 ◽  
Vol 43 (7) ◽  
pp. 2865-2869 ◽  
Author(s):  
Kaixin Xu ◽  
Longwei He ◽  
Yunzhen Yang ◽  
Weiying Lin

A two-photon turn-on fluorescent probe regulated by a PET mechanism has been engineered for detection of thiols and H2S in living cells, tissues and zebrafish.


Author(s):  
Yanan Lu ◽  
Xiaomin Shi ◽  
Wenlong Fan ◽  
Cory A. Black ◽  
Zhengliang Lu ◽  
...  

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