Expedient green-chemistry approaches for a one-pot synthesis of two series of novel 1,5-benzodiazepines via domino reactions

2020 ◽  
Vol 44 (25) ◽  
pp. 10428-10440
Author(s):  
Hai-tao Wu ◽  
Lan-zhi Wang

Unique green-chemistry approaches have been developed for the one-pot synthesis of two series of novel 1,5-benzodiazepines 4 and 5.

RSC Advances ◽  
2021 ◽  
Vol 11 (59) ◽  
pp. 37103-37111
Author(s):  
Farzaneh Shamsa ◽  
Alireza Motavalizadehkakhky ◽  
Rahele Zhiani ◽  
Jamshid Mehrzad ◽  
Malihe Sadat Hosseiny

The transmutation of waste into valuable materials has a special place in green chemistry.


2016 ◽  
Vol 42 (6) ◽  
pp. 5915-5926 ◽  
Author(s):  
Razieh Mohebat ◽  
Afshin Yazdani Elah Abadi ◽  
Malek-Taher Maghsoodlou ◽  
Mohsen Mohammadi

2018 ◽  
Vol 42 (24) ◽  
pp. 20032-20040 ◽  
Author(s):  
Yue-Wei Sun ◽  
Lan-Zhi Wang

A simple and highly efficient protocol for the one-pot synthesis of novel benzodiazepines, which fused tricyclic or tetracyclic systems containing aryl, carboxyl, ester and acyl groups, was developed. Libraries of 40 new compounds were successfully synthesized via three-component or domino reactions by using a mild catalyst (γ-Fe2O3@SiO2/CeCl3) in good to excellent yields (82–97%).


2020 ◽  
Vol 24 (20) ◽  
pp. 2341-2355
Author(s):  
Thaipparambil Aneeja ◽  
Sankaran Radhika ◽  
Mohan Neetha ◽  
Gopinathan Anilkumar

One-pot syntheses are a simple, efficient and easy methodology, which are widely used for the synthesis of organic compounds. Imidazoline is a valuable heterocyclic moiety used as a synthetic intermediate, chiral auxiliary, chiral catalyst and a ligand for asymmetric catalysis. Imidazole is a fundamental unit of biomolecules that can be easily prepared from imidazolines. The one-pot method is an impressive approach to synthesize organic compounds as it minimizes the reaction time, separation procedures, and ecological impact. Many significant one-pot methods such as N-bromosuccinimide mediated reaction, ring-opening of tetrahydrofuran, triflic anhydrate mediated reaction, etc. were reported for imidazoline synthesis. This review describes an overview of the one-pot synthesis of imidazolines and covers literature up to 2020.


2001 ◽  
Vol 2001 (4) ◽  
pp. 160-161 ◽  
Author(s):  
Hongyun Guo ◽  
Yunfa Zheng ◽  
Yongmin Zhang

α-Selenonitriles, α-selenoesters, and asymmetrical selenides can be readily obtained from the one-pot reaction of diselenides and active organic halides by a Sm/ZnCl2 system in DMF-H2O.


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