Highly efficient asymmetric bioreduction of 1-aryl-2-(azaaryl)ethanones. Chemoenzymatic synthesis of lanicemine

Highly Efficient ◽

Asymmetric Bioreduction

1-Aryl-2-(azaaryl)ethanols with ee > 99% have been prepared by KRED-catalyzed reduction of the ketone precursors. A chemoenzymatic synthesis of lanicemine is described.

Highly Efficient Chemoenzymatic Synthesis of Naturally Occurring and Non-Natural α-2,6-Linked Sialosides: AP. damsela α-2,6-Sialyltransferase with Extremely Flexible Donor–Substrate Specificity

Angewandte Chemie International Edition ◽

10.1002/anie.200600572 ◽

2006 ◽

Vol 45 (24) ◽

pp. 3938-3944 ◽

Cited By ~ 163

Author(s):

Hai Yu ◽

Shengshu Huang ◽

Harshal Chokhawala ◽

Mingchi Sun ◽

Haojie Zheng ◽

...

Keyword(s):

Substrate Specificity ◽

Highly Efficient ◽

Donor Substrate ◽

Naturally Occurring

One-pot chemoenzymatic synthesis of trolline and tetrahydroisoquinoline analogues

Chemical Communications ◽

10.1039/c7cc08024g ◽

2018 ◽

Vol 54 (11) ◽

pp. 1323-1326 ◽

Cited By ~ 19

Author(s):

Jianxiong Zhao ◽

Benjamin R. Lichman ◽

John M. Ward ◽

Helen C. Hailes

Keyword(s):

Natural Product ◽

One Pot ◽

A highly efficient one-pot asymmetric route to tetrahydroisoquinoline alkaloids including the natural product trolline is described.

Glycosynthases Enable a Highly Efficient Chemoenzymatic Synthesis ofN-Glycoproteins Carrying Intact NaturalN-Glycans

Journal of the American Chemical Society ◽

10.1021/ja8074677 ◽

2009 ◽

Vol 131 (6) ◽

pp. 2214-2223 ◽

Cited By ~ 141

Author(s):

Wei Huang ◽

Cishan Li ◽

Bing Li ◽

Midori Umekawa ◽

Kenji Yamamoto ◽

...

Keyword(s):

Highly Efficient Chemoenzymatic Synthesis of Methyl (R)-o-Chloromandelate, a Key Intermediate for Clopidogrel,viaAsymmetric Reduction with RecombinantEscherichia coli

Advanced Synthesis & Catalysis ◽

10.1002/adsc.200800292 ◽

2008 ◽

Vol 350 (13) ◽

pp. 2039-2044 ◽

Cited By ~ 84

Author(s):

Tadashi Ema ◽

Sayaka Ide ◽

Nobuyasu Okita ◽

Takashi Sakai

Keyword(s):

Highly efficient chemoenzymatic synthesis of β1–4-linked galactosides with promiscuous bacterial β1–4-galactosyltransferases

Chemical Communications ◽

10.1039/c0cc01381a ◽

2010 ◽

Vol 46 (33) ◽

pp. 6066 ◽

Cited By ~ 80

Author(s):

Kam Lau ◽

Vireak Thon ◽

Hai Yu ◽

Li Ding ◽

Yi Chen ◽

...

Keyword(s):

Highly Efficient Chemoenzymatic Synthesis of l-Phosphinothricin from N-Phenylacetyl-d,l-phosphinothricin by a Robust Immobilized Amidase

Journal of Agricultural and Food Chemistry ◽

10.1021/acs.jafc.0c06238 ◽

2020 ◽

Vol 68 (49) ◽

pp. 14549-14554

Author(s):

Chao-Ping Lin ◽

Yue Mao ◽

Ren-Chao Zheng ◽

Yu-Guo Zheng

Keyword(s):

Highly Efficient Chemoenzymatic Synthesis of α-Galactosyl Epitopes with a Recombinant α(1→3)-Galactosyltransferase

Journal of the American Chemical Society ◽

10.1021/ja9808898 ◽

1998 ◽

Vol 120 (27) ◽

pp. 6635-6638 ◽

Cited By ~ 82

Author(s):

Jianwen Fang ◽

Jun Li ◽

Xi Chen ◽

Yingnan Zhang ◽

Jianqiang Wang ◽

...

Keyword(s):

ChemInform Abstract: Highly Efficient Chemoenzymatic Synthesis of α-Galactosyl Epitopes with a Recombinant α(1→3)-Galactosyltransferase.

ChemInform ◽

10.1002/chin.199845215 ◽

2010 ◽

Vol 29 (45) ◽

pp. no-no

Author(s):

J. FANG ◽

J. LI ◽

X. CHEN ◽

Y. ZHANG ◽

J. WANG ◽

...

Keyword(s):

Highly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc4βCer

Chemical Communications ◽

10.1039/c7cc04090c ◽

2017 ◽

Vol 53 (59) ◽

pp. 8280-8283 ◽

Cited By ~ 11

Author(s):

Abhishek Santra ◽

Yanhong Li ◽

Hai Yu ◽

Teri J. Slack ◽

Peng George Wang ◽

...

Keyword(s):

One Pot ◽

α-Gal pentasaccharyl ceramide was synthesized using sequential one-pot multienzyme (OPME) systems with facile purification using a C18 cartridge followed by acylation.