scholarly journals Direct intramolecular double cross-dehydrogentive-coupling (CDC) cyclization of N-(2-pyridyl)amidines under metal-free conditions

RSC Advances ◽  
2019 ◽  
Vol 9 (72) ◽  
pp. 42172-42182 ◽  
Author(s):  
Fengping Yi ◽  
Chao Fu ◽  
Qihui Sun ◽  
Huazhen Wei ◽  
Genfa Yu ◽  
...  
Keyword(s):  
Nucleophilic Substitution ◽  
Substitution Reactions ◽  
Metal Free ◽  
Nucleophilic Substitution Reactions ◽  
Mild Conditions ◽  
Double Cross

A metal-free protocol to form 2-iminoimidazo[1,2-a]-pyridines from N-(2-pyridyl)amidines, in which the constructed heterocyclic skeletons are promoted by CBr4via radical or nucleophilic substitution reactions under mild conditions, is demonstrated.

scholarly journals Water promoted allylic nucleophilic substitution reactions of (E)-1,3 diphenylallyl acetate

2018 ◽  
Vol 20 (2) ◽  
pp. 425-430 ◽  
Author(s):  
Seema A. Ghorpade ◽  
Dinesh N. Sawant ◽  
Arwa Makki ◽  
Nagaiyan Sekar ◽  
Jörg Eppinger
Keyword(s):  
Transition Metal ◽  
Nucleophilic Substitution ◽  
Allylic Alkylation ◽  
Substitution Reactions ◽  
Allylic Amination ◽  
Metal Free ◽  
Nucleophilic Substitution Reactions ◽  
Water Based

A transition metal free, reagent free, only water based, greener protocol for the allylic alkylation, allylic amination, and O-allylation of (E)-1,3-diphenylallyl acetate is described.

The Nucleophilic Substitution Reactions of 5- and 7-Chloro-4,6-dinitrobenzofurazan 1-Oxide by Aromatic Amines.

1985 ◽  
Vol 38 (3) ◽  
pp. 435 ◽  
Author(s):  
RW Read ◽  
WP Norris
Keyword(s):  
Nucleophilic Substitution ◽  
Aromatic Amines ◽  
Equilibrium Mixture ◽  
Substitution Reactions ◽  
Isomeric Mixture ◽  
Nucleophilic Substitution Reactions ◽  
Mild Conditions ◽  
Structural Assignment

7-Chloro-4,6-dinitrobenzofurazan 1-oxide is a powerful electrophile which reacts with a variety of primary and secondary aromatic amines, even those with deactivating substituents , to give arylamino - benzofurazan oxides under mild conditions. Tertiary aromatic amines react through carbon to give aminoarylbenzofurazan oxides. During, or as a consequence of, the substitution reactions, tautomerism occurs to give in all but one example an equilibrium mixture of 5- and 7-substituted 4,6-dinitrobenzofurazan oxides in which the latter predominates. Thus 5-chloro-4,6-dinitrobenzofurazan 1-oxide and 7- chloro-4,6-dinitrobenzofurazan 1-oxide both react with aniline to yield the same isomeric mixture of products: 4,6-dinitro-7- phenylaminobenzofurazan oxide (predominantly 1-oxide) (major) and 4,6- dinitro-5-phenylaminobenzofurazan 1-oxide (minor). The 5- and 7- phenylamino 4,6-dinitrobenzofurazans were prepared to assist in structural assignment of the N-oxides.

The unexpected reactivity of 9-iodo-nido-carborane: from nucleophilic substitution reactions to the synthesis of tricobalt tris(dicarbollide) Na[4,4′,4′′-(MeOCH2CH2O)3-3,3′,3′′-Co3(μ3-O)(μ3-S)(1,2-C2B9H10)3]

2021 ◽  
Vol 50 (7) ◽  
pp. 2671-2688
Author(s):  
Marina Yu. Stogniy ◽  
Sergey A. Anufriev ◽  
Akim V. Shmal'ko ◽  
Sergey M. Antropov ◽  
Aleksei A. Anisimov ◽  
...  
Keyword(s):  
Nucleophilic Substitution ◽  
Substitution Reactions ◽  
Nucleophilic Substitution Reactions

An unusual reactivity of 9-iodo-nido-carborane [9-I-7,8-C2B9H11]− towards nucleophiles under strong basic conditions was revealed.

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