Homo- and heteroleptic trimethoxy terpyridine–Cu(ii) complexes: synthesis, characterization, DNA/BSA binding, DNA cleavage and cytotoxicity studies

2020 ◽  
Vol 49 (13) ◽  
pp. 4100-4113 ◽  
Author(s):  
Surbhi Jain ◽  
Kishalay Bhar ◽  
Sandeep Kumar ◽  
Shreetama Bandyopadhyaya ◽  
Suman Tapryal ◽  
...  
Keyword(s):  
Dna Cleavage ◽  
Bsa Binding ◽  
Cytotoxicity Studies

In the current study, four novel mononuclear Cu(ii) complexes with terpyridine (L) and different co-ligands (phen, bipy, and imd) were synthesized and characterized in detail, where L is 4′-(3,4,5-trimethoxyphenyl)-2,2′:6′,2′′-terpyridine.

Synthesis, X-ray crystal structure, DNA/BSA binding, DNA cleavage and cytotoxicity studies of phenanthroline based copper(II)/zinc(II) complexes

BioMetals ◽  
2017 ◽  
Vol 30 (4) ◽  
pp. 575-587 ◽  
Author(s):  
Qingming Wang ◽  
Han Mao ◽  
Wenling Wang ◽  
Huimin Zhu ◽  
Lihui Dai ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Cleavage ◽  
X Ray ◽  
Bsa Binding ◽  
Cytotoxicity Studies

Copper(II) Complexes of 2-methyl-8-hydroxyquinoline and tri/diimine Co-ligand: DFT Calculation, DNA and BSA Binding, DNA Cleavage, Cytotoxicity and Induction of Apoptosis

2021 ◽  
Author(s):  
Sangeetha Somasundaram ◽  
Tamilarasan Ajaykamal ◽  
Murali Mariappan
Keyword(s):  
Crystal Structure ◽  
Dna Cleavage ◽  
Dft Calculation ◽  
Mixed Ligand ◽  
Bsa Binding ◽  
Induction Of Apoptosis

The mixed ligand copper(II) complexes [Cu(terpy)(mq)]ClO4 (1) and [Cu(phen)(mq)]ClO4 (2), where terpy = 2,2’:6’,2’’-terpyridine, phen = 1,10-phenanthroline and H(mq) = 2-methyl-8-hydroxyquinoline have been synthesised. The crystal structure of 1 discloses...

DNA/BSA binding, DNA cleavage and electrochemical properties of new multidentate copper(ii) complexes

RSC Advances ◽  
2014 ◽  
Vol 4 (77) ◽  
pp. 40763-40775 ◽  
Author(s):  
Elumalai Sundaravadivel ◽  
Sairaj Vedavalli ◽  
Muthusamy Kandaswamy ◽  
Babu Varghese ◽  
Perumal Madankumar
Keyword(s):  
Electrochemical Properties ◽  
Dna Cleavage ◽  
Antimicrobial Activities ◽  
Bsa Binding

A new series of multidentate copper(ii) complexes [Cu(L1−5)](ClO4) (1–5) were synthesized and characterized for their DNA/BSA binding, DNA cleavage, cytotoxic properties and antimicrobial activities.

scholarly journals Cu(II) Complexes of Isoniazid Schiff Bases: DNA/BSA Binding and Cytotoxicity Studies on A549 Cell Line

2014 ◽  
Vol 2014 ◽  
pp. 1-14 ◽  
Author(s):  
Pulipaka Ramadevi ◽  
Rinky Singh ◽  
Akhilesh Prajapati ◽  
Sarita Gupta ◽  
Debjani Chakraborty
Keyword(s):  
Human Lung Cancer ◽  
Azomethine Nitrogen ◽  
Planar Geometry ◽  
Lung Cancer Cell ◽  
Bsa Binding ◽  
Square Planar ◽  
Cytotoxicity Studies ◽  
Staining Techniques ◽  
Bovine Serum Albumin Binding ◽  
Ct Dna

A series of isonicotinoyl hydrazones have been synthesized via template method and were complexed to Cu(II). The ligands are coordinated to Cu(II) ion through the enolic oxygen and azomethine nitrogen resulting in a square planar geometry. The CT-DNA and bovine serum albumin binding propensities of the compounds were determined spectrophotometrically, the results of which indicate good binding propensity of complexes to DNA and BSA with high binding constant values. Furthermore, the compounds have been investigated for their cytotoxicities on A549 human lung cancer cell. Also the mode of cell death was examined employing various staining techniques and was found to be apoptotic.

Evaluation of DNA, BSA binding, DNA cleavage and antimicrobial activity of ytterbium(III) complex containing 2,2'-bipyridine ligand

2019 ◽  
pp. 1-15 ◽  
Author(s):  
Zahra Aramesh-Boroujeni ◽  
Shohreh Jahani ◽  
Mozhgan Khorasani-Motlagh ◽  
Kagan Kerman ◽  
Meissam Noroozifar
Keyword(s):  
Antimicrobial Activity ◽  
Dna Cleavage ◽  
Bsa Binding ◽  
Bipyridine Ligand

DNA(CT), protein(BSA) binding studies, anti-oxidant and cytotoxicity studies of new binuclear Ni(II) complexes containing 4(N)-substituted thiosemicarbazones

2016 ◽  
Vol 453 ◽  
pp. 547-558 ◽  
Author(s):  
G . Kalaiarasi ◽  
C. Umadevi ◽  
A. Shanmugapriya ◽  
P. Kalaivani ◽  
F. Dallemer ◽  
...  
Keyword(s):  
Binding Studies ◽  
Bsa Binding ◽  
Cytotoxicity Studies ◽  
Anti Oxidant

Synthesis, DNA binding, photo-induced DNA cleavage, cytotoxicity studies of a family of heavy rare earth complexes

2013 ◽  
Vol 127 ◽  
pp. 39-45 ◽  
Author(s):  
Gong-Jun Chen ◽  
Zhi-Gang Wang ◽  
Xin Qiao ◽  
Jing-Yuan Xu ◽  
Jin-Lei Tian ◽  
...  
Keyword(s):  
Rare Earth ◽  
Dna Binding ◽  
Dna Cleavage ◽  
Rare Earth Complexes ◽  
Heavy Rare Earth ◽  
Cytotoxicity Studies
Sign in / Sign up

Export Citation Format

Share Document