Organocatalytic asymmetric addition of thioglycolates to o-quinone methides: a route to 5-substituted-5H-benzoxathiepine-2(3H)-ones

Quinone Methides ◽

The first enantioselective synthesis of 5-substituted-5H-benzoxathiepine-2(3H)-ones via organocatalytic asymmetric addition of thioglycolates to o-quinone methides followed by cyclization.

Catalytic enantioselective synthesis of macrodiolides and their application in chiral recognition

Chemical Science ◽

10.1039/d0sc06162j ◽

2021 ◽

Author(s):

Wanlong Xiao ◽

Yuhao Mo ◽

Jing Guo ◽

Zhishan Su ◽

Shunxi Dong ◽

...

Keyword(s):

Chiral Recognition ◽

Quinone Methides ◽

New Type

A new type of C2-symmetric chiral macrodiolides are readily obtained via chiral N,Nʹ-dioxide-scandium(III) complex-promoted asymmetric tandem Friedel-Crafts alkylation/intermolecular macrolactonization of ortho-quinone methides with C3-substituted indoles. This protocol provides an array...

ChemInform Abstract: Enantioselective Synthesis of 3-Alkynyl-3-hydroxyindolin-2-ones by Copper-Catalyzed Asymmetric Addition of Terminal Alkynes to Isatins.

ChemInform ◽

10.1002/chin.201640118 ◽

2016 ◽

Vol 47 (40) ◽

Author(s):

Ning Xu ◽

Da-Wei Gu ◽

Jing Zi ◽

Xin-Yan Wu ◽

Xun-Xiang Guo

Keyword(s):

Terminal Alkynes ◽

Catalytic Asymmetric Addition of Alkyl Enol Ethers to 1,2-Dicarbonyl Compounds: Highly Enantioselective Synthesis of Substituted 3-Alkyl-3-Hydroxyoxindoles

Angewandte Chemie ◽

10.1002/ange.201007145 ◽

2011 ◽

Vol 123 (11) ◽

pp. 2621-2625 ◽

Cited By ~ 32

Author(s):

Ke Zheng ◽

Chengkai Yin ◽

Xiaohua Liu ◽

Lili Lin ◽

Xiaoming Feng

Keyword(s):

Asymmetric Addition ◽

Dicarbonyl Compounds ◽

Enol Ethers ◽

Catalytic Asymmetric ◽

Alkyl Enol Ethers

ChemInform Abstract: Catalytic Asymmetric Addition of Meldrum′s Acid, Malononitrile, and 1,3-Dicarbonyls to ortho-Quinone Methides Generated in situ under Basic Conditions.

ChemInform ◽

10.1002/chin.201535164 ◽

2015 ◽

Vol 46 (35) ◽

pp. no-no

Author(s):

Lorenzo Caruana ◽

Martina Mondatori ◽

Vasco Corti ◽

Sara Morales ◽

Andrea Mazzanti ◽

...

Keyword(s):

Quinone Methides ◽

Asymmetric Addition ◽

Catalytic Asymmetric

ChemInform Abstract: A Highly Enantioselective Synthesis of Chiral Allylic Alcohols by Asymmetric Addition of Novel Mixed Reagents of Trialkenylbismuthines/Dialkylzincs to Aldehydes.

ChemInform ◽

10.1002/chin.200817065 ◽

2008 ◽

Vol 39 (17) ◽

Author(s):

Itaru Sato ◽

Noriaki Asakura ◽

Taizo Iwashita

Keyword(s):

Allylic Alcohols ◽

ChemInform Abstract: Organocatalytic Asymmetric Addition of Alcohols to Cyclic Trifluoromethyl Ketimines: Highly Enantioselective Synthesis of Chiral N,O-Ketals.

ChemInform ◽

10.1002/chin.201646179 ◽

2016 ◽

Vol 47 (46) ◽

Author(s):

Ding Zhou ◽

Xueting Yu ◽

Jian Zhang ◽

Wei Wang ◽

Hexin Xie

Keyword(s):

ChemInform Abstract: Broensted Acid Catalyzed, Conjugate Addition of β-Dicarbonyls to in situ Generated ortho-Quinone Methides-Enantioselective Synthesis of 4-Aryl-4H-chromenes.

ChemInform ◽

10.1002/chin.201504140 ◽

2015 ◽

Vol 46 (4) ◽

pp. no-no

Author(s):

Osama El-Sepelgy ◽

Stefan Haseloff ◽

Santosh Kumar Alamsetti ◽

Christoph Schneider

Keyword(s):

Conjugate Addition ◽

Quinone Methides ◽

Acid Catalyzed

Core-structure-inspired asymmetric addition reactions: enantioselective synthesis of dihydrobenzoxazinone- and dihydroquinazolinone-based anti-HIV agents

Chemical Society Reviews ◽

10.1039/c5cs00342c ◽

2015 ◽

Vol 44 (21) ◽

pp. 7439-7448 ◽

Cited By ~ 46

Author(s):

Shen Li ◽

Jun-An Ma

Keyword(s):

Asymmetric Synthesis ◽

Core Structure ◽

Addition Reactions ◽

Asymmetric Addition ◽

Anti Hiv Agents ◽

Anti Hiv

An overview of the asymmetric synthesis of dihydrobenzoxazinone- and dihydroquinazolinone-based anti-HIV agents (Efavirenz, DPC 961, DPC 963, DPC 083) and analogues was presented.