Peroxide- and transition metal-free electrochemical synthesis of α,β-epoxy ketones

2021 ◽  
Vol 19 (11) ◽  
pp. 2481-2486
Author(s):  
Mengxun Zhang ◽  
Tie Chen ◽  
Shisong Fang ◽  
Weihua Wu ◽  
Xin Wang ◽  
...  
Keyword(s):  
Transition Metal ◽  
Electrochemical Synthesis ◽  
Electrochemical Method ◽  
Metal Free ◽  
Epoxy Ketones

A novel electrochemical method for the synthesis of α,β-epoxy ketones is reported.

scholarly journals Electrochemical Synthesis of Thienoacene Derivatives: Transition‐Metal‐Free Dehydrogenative C−S Coupling Promoted by a Halogen Mediator

2020 ◽  
Vol 59 (20) ◽  
pp. 7803-7807 ◽  
Author(s):  
Koichi Mitsudo ◽  
Ren Matsuo ◽  
Toki Yonezawa ◽  
Haruka Inoue ◽  
Hiroki Mandai ◽  
...  
Keyword(s):  
Transition Metal ◽  
Electrochemical Synthesis ◽  
Metal Free

Selective and Scalable Dehydrogenative Electrochemical Synthesis of 3,3′,5,5′-Tetramethyl-2,2′-biphenol

Synlett ◽  
2019 ◽  
Vol 30 (18) ◽  
pp. 2062-2067 ◽  
Author(s):  
Maximilian Selt ◽  
Stamo Mentizi ◽  
Dieter Schollmeyer ◽  
Robert Franke ◽  
Siegfried R. Waldvogel
Keyword(s):  
Transition Metal ◽  
Electrochemical Synthesis ◽  
Building Block ◽  
Electrochemical Method ◽  
Transition Metal Catalysis ◽  
Side Reactions ◽  
Metal Catalysis ◽  
Byproduct Formation ◽  
Chemical Strategies

3,3′,5,5′-Tetramethyl-2,2′-biphenol is a compound of high technical significance, as it exhibits superior properties as building block for ligands in the transition-metal catalysis. However, side reactions and overoxidation are challenging issues in the conventional synthesis of this particular biphenol. Here, an electrochemical method is presented as powerful and sustainable alternative to conventional chemical strategies, which gives good yields up to 51%. Despite using inexpensive and well-available bromide-containing supporting electrolytes, the issue of bromination and general byproduct formation is effectively suppressed by adding water to the electrolyte. Additionally, the scalability of this method was demonstrated by conducting the electrolysis on a 122 g scale.

A transition-metal-free, one-pot procedure for the synthesis of α,β-epoxy ketones by oxidative coupling of alkenes and aldehydes via base catalysis

2015 ◽  
Vol 51 (6) ◽  
pp. 1012-1015 ◽  
Author(s):  
Qingping Ke ◽  
Bingyan Zhang ◽  
Bolun Hu ◽  
Yangxin Jin ◽  
Guanzhong Lu
Keyword(s):  
Transition Metal ◽  
Oxidative Coupling ◽  
Base Catalysis ◽  
One Pot ◽  
Metal Free ◽  
New Strategy ◽  
Epoxy Ketones

A new strategy for the synthesis of epoxides is presented.

ChemInform Abstract: Selectfluor-Mediated Simultaneous Cleavage of C-O and C-C Bonds in α,β-Epoxy Ketones under Transition-Metal-Free Conditions: A Route to 1,2-Diketones.

ChemInform ◽  
2015 ◽  
Vol 46 (45) ◽  
pp. no-no
Author(s):  
Heng Wang ◽  
Shaobo Ren ◽  
Jian Zhang ◽  
Wei Zhang ◽  
Yunkui Liu
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
Epoxy Ketones

scholarly journals Electrochemical Synthesis of Thienoacene Derivatives: Transition‐Metal‐Free Dehydrogenative C−S Coupling Promoted by a Halogen Mediator

2020 ◽  
Vol 132 (20) ◽  
pp. 7877-7881
Author(s):  
Koichi Mitsudo ◽  
Ren Matsuo ◽  
Toki Yonezawa ◽  
Haruka Inoue ◽  
Hiroki Mandai ◽  
...  
Keyword(s):  
Transition Metal ◽  
Electrochemical Synthesis ◽  
Metal Free

Selectfluor-Mediated Simultaneous Cleavage of C–O and C–C Bonds in α,β-Epoxy Ketones Under Transition-Metal-Free Conditions: A Route to 1,2-Diketones

2015 ◽  
Vol 80 (13) ◽  
pp. 6856-6863 ◽  
Author(s):  
Heng Wang ◽  
Shaobo Ren ◽  
Jian Zhang ◽  
Wei Zhang ◽  
Yunkui Liu
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
Epoxy Ketones

ChemInform Abstract: A Transition-Metal-Free, One-Pot Procedure for the Synthesis of α,β-Epoxy Ketones by Oxidative Coupling of Alkenes and Aldehydes via Base Catalysis.

ChemInform ◽  
2015 ◽  
Vol 46 (25) ◽  
pp. no-no
Author(s):  
Qingping Ke ◽  
Bingyan Zhang ◽  
Bolun Hu ◽  
Yangxin Jin ◽  
Guanzhong Lu
Keyword(s):  
Transition Metal ◽  
Oxidative Coupling ◽  
Base Catalysis ◽  
One Pot ◽  
Metal Free ◽  
Epoxy Ketones

scholarly journals Mild electrochemical synthesis of metal phosphides with dibenzo-7-phosphanorbornadiene derivatives: mechanistic insights and application to proton reduction in water

2018 ◽  
Vol 54 (7) ◽  
pp. 767-770 ◽  
Author(s):  
Naoki Shida ◽  
Joshua A. Buss ◽  
Theodor Agapie
Keyword(s):  
Transition Metal ◽  
Electrochemical Synthesis ◽  
Electrochemical Method ◽  
Proton Reduction ◽  
Metal Phosphide ◽  
Metal Phosphides ◽  
Transition Metal Phosphide

Transition metal phosphide films were synthesized using a mild electrochemical method.

Transition-metal-free catalytic hydroboration reduction of amides to amines

2020 ◽  
Vol 7 (21) ◽  
pp. 3515-3520
Author(s):  
Wubing Yao ◽  
Jiali Wang ◽  
Aiguo Zhong ◽  
Shiliang Wang ◽  
Yinlin Shao
Keyword(s):  
Transition Metal ◽  
Selective Catalytic Reduction ◽  
Catalytic Reduction ◽  
Value Added ◽  
Metal Free

The selective catalytic reduction of amides to value-added amine products is a desirable but challenging transformation.

Deaminative carbonylative thioesterification of activated alkylamines with thiophenols under transition-metal-free conditions

2021 ◽  
Author(s):  
Fengqian Zhao ◽  
Xiao-Feng Wu
Keyword(s):  
Free Radical ◽  
Transition Metal ◽  
Metal Free

A transition-metal-free radical carbonylation of activated alkylamines with thiophenols has been successfully developed. Various thioesters were selectively produced with moderate to good yields.

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