scholarly journals Residue-based propensity of aggregation in the Tau amyloidogenic hexapeptides AcPHF6* and AcPHF6

RSC Advances ◽  
2020 ◽  
Vol 10 (46) ◽  
pp. 27331-27335
Author(s):  
Abha Dangi ◽  
Abhishek Ankur Balmik ◽  
Archana Kisan Ghorpade ◽  
Nalini Vijay Gorantla ◽  
Shweta Kishor Sonawane ◽  
...  
Keyword(s):  
Alanine Substitution

In the alanine mutant peptides of AcPHF6* and AcPHF6, only the peptides with glutamine to alanine substitution show aggregation akin to that of the parent peptides.

Activation of LA-N-2 cell phospholipases by single alanine substitution analogs of amyloid β peptide (25-35)

FEBS Letters ◽  
1997 ◽  
Vol 405 (1) ◽  
pp. 65-67 ◽  
Author(s):  
I.N Singh ◽  
K Sato ◽  
A Takashima ◽  
J.N Kanfer
Keyword(s):  
Amyloid Β ◽  
Amyloid Β Peptide ◽  
Alanine Substitution

Native Alanine Substitution in the Glycine Hinge Modulates Conformational Flexibility of Heme Nitric Oxide/Oxygen (H-NOX) Sensing Proteins

2018 ◽  
Vol 13 (6) ◽  
pp. 1631-1639 ◽  
Author(s):  
Charles W. Hespen ◽  
Joel J. Bruegger ◽  
Yirui Guo ◽  
Michael A. Marletta
Keyword(s):  
Nitric Oxide ◽  
Conformational Flexibility ◽  
Alanine Substitution

scholarly journals Enhanced antimicrobial activity of H-lysozyme (107–115) by rational alanine substitution

2009 ◽  
Vol 25 ◽  
pp. S4-S5
Author(s):  
R. González ◽  
A.F. Albericio ◽  
O. Cascone ◽  
N.B. Iannucci
Keyword(s):  
Antimicrobial Activity ◽  
Alanine Substitution

Improving the Catalytic Activity and Thermostability of MAS1 Lipase by Alanine Substitution

2018 ◽  
Vol 60 (4) ◽  
pp. 319-328 ◽  
Author(s):  
Ge Zhao ◽  
Jianrong Wang ◽  
Qingyun Tang ◽  
Dongming Lan ◽  
Yonghua Wang
Keyword(s):  
Catalytic Activity ◽  
Alanine Substitution

A form of autosomal dominant spondyloepiphyseal dysplasia is caused by a glycine to alanine substitution in the COL2A1 gene

2006 ◽  
Vol 15 (4) ◽  
pp. 197-202 ◽  
Author(s):  
Gabrielle S. Sellick ◽  
Kristein P. Hoornaert ◽  
Geert R. Mortier ◽  
Catherine King ◽  
Claire L. Dolling ◽  
...  
Keyword(s):  
Autosomal Dominant ◽  
Col2a1 Gene ◽  
Alanine Substitution ◽  
Spondyloepiphyseal Dysplasia

scholarly journals β-Methylamino-L-alanine substitution of serine in SOD1 suggests a direct role in ALS etiology

2019 ◽  
Vol 15 (7) ◽  
pp. e1007225 ◽  
Author(s):  
Elizabeth A. Proctor ◽  
David D. Mowrey ◽  
Nikolay V. Dokholyan
Keyword(s):  
Direct Role ◽  
Alanine Substitution
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