Cycloaddition of N-sulfonyl and N-sulfamoyl azides with alkynes in aqueous media for the selective synthesis of 1,2,3-triazoles

2021 ◽  
Author(s):  
Thumpati Prasanth ◽  
Gargi Chakraborti ◽  
Tirtha Mandal ◽  
Velayutham Ravichandiran ◽  
Jyotirmayee Dash
Keyword(s):  
Aqueous Media ◽  
Selective Synthesis ◽  
Terminal Alkynes ◽  
Amide Derivatives

The cycloaddition of N-sulfonyl and N-sulfamoyl azides with terminal alkynes generally produces amide derivatives via ketenimine intermediates. We herein delineate a Cu(I) catalyzed method using a prolinamide ligand that selectively...

Reactions of salicylaldehydes with activated terminal alkynes in aqueous media: synthesis of 3-substituted 4-hydroxy chromenes as potential cytotoxic agents

RSC Advances ◽  
2014 ◽  
Vol 4 (47) ◽  
pp. 24870 ◽  
Author(s):  
Shambhu Nath Singh ◽  
Ramu Bopanni ◽  
Sarva Jayaprakash ◽  
K. Venkateshwara Reddy ◽  
Mohd Ashraf Ashfaq ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Cytotoxic Agents ◽  
Terminal Alkynes

scholarly journals Bis-NHC–Ag/Pd(OAc)2 Catalytic System Catalyzed Transfer Hydrogenation Reaction

Catalysts ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 8
Author(s):  
Hui-Ju Chen ◽  
Chien-Cheng Chiu ◽  
Tsui Wang ◽  
Dong-Sheng Lee ◽  
Ta-Jung Lu
Keyword(s):  
Functional Groups ◽  
Catalytic System ◽  
High Efficiency ◽  
Aqueous Media ◽  
Hydrogenation Reaction ◽  
Transfer Hydrogenation ◽  
Terminal Alkynes ◽  
Wide Range ◽  
Transfer Hydrogenation Reaction

The bis-NHC–Ag/Pd(OAc)2 catalytic system (NHC = N-heterocyclic carbene), a combination of bis-NHC–Ag complex and Pd(OAc)2, was found to be a smart catalyst in the Pd-catalyzed transfer hydrogenation of various functionalized arenes and internal/terminal alkynes. The catalytic system demonstrated high efficiency for the reduction of a wide range of various functional groups such as carbonyls, alkynes, olefins, and nitro groups in good to excellent yields and high chemoselectivity for the reduction of functional groups. In addition, the protocol was successfully exploited to stereoselectivity for the transformation of alkynes to alkenes in aqueous media under air. This methodology successfully provided an alternative useful protocol for reducing various functional groups and a simple operational protocol for transfer hydrogenation.

Novel Intramolecular Allylindination of Terminal Alkynes in Aqueous Media.

ChemInform ◽  
2003 ◽  
Vol 34 (11) ◽  
Author(s):  
Matthew M. Salter ◽  
Sofia Sardo-Inffiri
Keyword(s):  
Aqueous Media ◽  
Terminal Alkynes

Ruthenium-PromotedZ-Selective Head-to-Head Dimerization of Terminal Alkynes in Organic and Aqueous Media

2005 ◽  
Vol 24 (18) ◽  
pp. 4330-4332 ◽  
Author(s):  
Xingguo Chen ◽  
Peng Xue ◽  
Herman H. Y. Sung ◽  
Ian D. Williams ◽  
Maurizio Peruzzini ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Terminal Alkynes

Synthesis of aromatic terminal allenes and aliphatic terminal alkynes from hydrazones using calcium carbide as an acetylene source

2020 ◽  
Vol 7 (4) ◽  
pp. 702-708 ◽  
Author(s):  
Lei Gao ◽  
Zheng Li
Keyword(s):  
Calcium Carbide ◽  
Selective Synthesis ◽  
Terminal Alkynes ◽  
Simple Method

A simple method for the selective synthesis of aromatic terminal allenes and aliphatic terminal alkynes from the reactions of calcium carbide with ketone and aldehyde p-tosylhydrazones using copper as a mediator is described.

Selective synthesis of (Z)-2-enynyl-2-hydroxy-imidazolidine-4,5-diones via Cu(i)-mediated multicomponent coupling of terminal alkynes, carbodiimides and oxalyl chloride

2014 ◽  
Vol 12 (21) ◽  
pp. 3336-3339 ◽  
Author(s):  
Fei Zhao ◽  
Yuexing Li ◽  
Yang Wang ◽  
Wen-Xiong Zhang ◽  
Zhenfeng Xi
Keyword(s):  
Oxalyl Chloride ◽  
Selective Synthesis ◽  
Terminal Alkynes ◽  
Geminal Coupling ◽  
Multicomponent Coupling

(Z)-2-Enynyl-2-hydroxy-imidazolidine-4,5-diones are synthesized via Cu(i)-mediated (Z)-selective geminal coupling among two terminal alkynes, carbodiimides, and oxalyl chloride. Further transformation is explored.

The ruthenium-catalysed selective synthesis of mono-deuterated terminal alkynes

2016 ◽  
Vol 52 (24) ◽  
pp. 4509-4512 ◽  
Author(s):  
Basujit Chatterjee ◽  
Chidambaram Gunanathan
Keyword(s):  
Catalytic System ◽  
Deuterium Oxide ◽  
Selective Synthesis ◽  
Terminal Alkynes ◽  
Selective Activation ◽  
Highly Efficient ◽  
Chemoselective Synthesis ◽  
Reaction Proceeds

A highly efficient catalytic system is reported for chemoselective synthesis of mono-deuterated terminal alkynes using deuterium oxide in which the reaction proceeds via Ru–acetylide intermediates formed by selective activation of the sp-CH bond.

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