Palladium Oxidative Addition Complexes Enabled Synthesis of Amino-Substituted Indolyl-4(3H)-quinazolinones and Their Antitumor Activity Evaluation

2022 ◽  
Author(s):  
Qingjiang Li ◽  
Zhi Jiang ◽  
Dan-Dan Zhao ◽  
Yu-Tao Hu ◽  
Yong Rao ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Potential Application ◽  
Oxidative Addition ◽  
Structural Motif ◽  
Activity Evaluation ◽  
Direct Modification

The indolyl-4(3H)-quinazolinone core is an important structural motif in functional molecules. However, few methods exist for the direct modification of which limit its potential application. Reported herein is a palladium-mediated...

Synthesis and antitumor activity evaluation of some thienopyrimidine derivatives

2019 ◽  
Vol 50 (3) ◽  
pp. 399-411 ◽  
Author(s):  
Amira T. A. Mohamed ◽  
Mohsen K. Abou-Elregal ◽  
Ahmed S. A. Youssef ◽  
Magdy M. Hemdan ◽  
Sandy S. Samir ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Activity Evaluation

Synthesis and Antitumor Activity Evaluation of Novel Pyrimidoquinoline Derivatives

2021 ◽  
pp. 1-15
Author(s):  
Mohammad Eghtedari ◽  
Marjan Azimzadeh Arani ◽  
Yaghoub Sarrafi ◽  
Mohammad Shafiei ◽  
Kamal Alimohammadi ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Activity Evaluation

Design, synthesis, and antitumor activity evaluation of steroidal oximes

2021 ◽  
pp. 116360
Author(s):  
Ana R. Gomes ◽  
Ana S. Pires ◽  
Ana M. Abrantes ◽  
Ana C. Gonçalves ◽  
Saul C. Costa ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Design Synthesis ◽  
Activity Evaluation

Design, synthesis and antitumor activity evaluation of novel HDAC inhibitors with tetrahydrobenzothiazole as the skeleton

2021 ◽  
Vol 108 ◽  
pp. 104652
Author(s):  
Simin Sun ◽  
Wenwen Zhao ◽  
Yongliang Li ◽  
Ziwei Chi ◽  
Xixi Fang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Hdac Inhibitors ◽  
Design Synthesis ◽  
Activity Evaluation

Synthesis and antitumor activity evaluation of novel oleanolic acid derivatives

2017 ◽  
Vol 19 (10) ◽  
pp. 1000-1010 ◽  
Author(s):  
Yan-Qiu Meng ◽  
Yu-Wei Zhao ◽  
Zhen-Yu Kuai ◽  
Li-Wei Liu ◽  
Wei Li
Keyword(s):  
Antitumor Activity ◽  
Oleanolic Acid ◽  
Activity Evaluation

Synthesis and antitumor activity evaluation of some schiff bases derived from 2-aminothiazole derivatives

2007 ◽  
Vol 18 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Xin Zhou ◽  
Ling Shao ◽  
Zhong Jin ◽  
Jian-Bing Liu ◽  
Hong Dai ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Schiff Bases ◽  
Activity Evaluation

Synthesis, antitumor activity evaluation and mechanistic study of novel hederacolchiside A1 derivatives bearing an aryl triazole moiety

2018 ◽  
Vol 26 (14) ◽  
pp. 4025-4033 ◽  
Author(s):  
Hui-ning Li ◽  
Hui Wang ◽  
Zhi-peng Wang ◽  
Hai-ning Yan ◽  
Miao Zhang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Mechanistic Study ◽  
Activity Evaluation

Synthesis of furo[3,2‐ g ]chromones under microwave irradiation and their antitumor activity evaluation

2019 ◽  
Vol 57 (2) ◽  
pp. 731-743
Author(s):  
Sherifa M. Abu‐Bakr ◽  
Maha D. Khidre ◽  
Mohamed A. Omar ◽  
Samira A. Swelam ◽  
Hanem M. Awad
Keyword(s):  
Antitumor Activity ◽  
Microwave Irradiation ◽  
Activity Evaluation
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