Role of myristoylation in the intracellular targeting of neuronal calcium sensor (NCS) proteins

2003 ◽  
Vol 31 (5) ◽  
pp. 963-965 ◽  
Author(s):  
D.W. O'Callaghan ◽  
R.D. Burgoyne
Keyword(s):  
Potassium Channel ◽  
Intracellular Localization ◽  
Calcium Signal ◽  
Calcium Sensor ◽  
Calcium Signals ◽  
Interacting Protein ◽  
Neuronal Calcium Sensor ◽  
Intracellular Targeting ◽  
Sensor Proteins

The control of the intracellular localization of NCS (neuronal calcium sensor) proteins is of importance for their ability to respond appropriately to differing calcium signals. We examine the localization of three NCS proteins: NCS-1, KChIP-1 (potassium-channel-interacting protein 1) and hippocalcin. Additionally, the [Ca2+] dependency of the calcium-induced translocation of hippocalcin is investigated. The implications of the differential targeting of these proteins on calcium signal interpretation are considered.

Ca2+-Myristoyl Switch in Neuronal Calcium Sensor-1: A Role of C-Terminal Segment

2015 ◽  
Vol 14 (4) ◽  
pp. 437-451 ◽  
Author(s):  
Viktoriia Baksheeva ◽  
Aliya Nazipova ◽  
Dmitry Zinchenko ◽  
Marina Serebryakova ◽  
Ivan Senin ◽  
...  
Keyword(s):  
Terminal Segment ◽  
Calcium Sensor ◽  
Neuronal Calcium Sensor ◽  
Myristoyl Switch

scholarly journals Differential Use of Myristoyl Groups on Neuronal Calcium Sensor Proteins as a Determinant of Spatio-temporal Aspects of Ca2+Signal Transduction

2002 ◽  
Vol 277 (16) ◽  
pp. 14227-14237 ◽  
Author(s):  
Dermott W. O'Callaghan ◽  
Lenka Ivings ◽  
Jamie L. Weiss ◽  
Michael C. Ashby ◽  
Alexei V. Tepikin ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Calcium Sensor ◽  
Neuronal Calcium Sensor ◽  
Temporal Aspects ◽  
Spatio Temporal ◽  
Sensor Proteins ◽  
Calcium Sensor Proteins

scholarly journals Role of the Trp169 Residue in Neuronal Calcium Sensor Dream

2021 ◽  
Vol 120 (3) ◽  
pp. 296a
Author(s):  
Maria D Santiago ◽  
Jaroslava Miksovska
Keyword(s):  
Calcium Sensor ◽  
Neuronal Calcium Sensor
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