Follow-up by cytogenetic and fluorescence in situ hybridization analysis of allogeneic bone marrow transplantation in two children with Fanconi's anaemia in transformation

2000 ◽  
Vol 111 (1) ◽  
pp. 329-333 ◽  
Author(s):  
M. Ortega ◽  
M. R. Caballin ◽  
J. J. Ortega ◽  
T. Olive ◽  
M. D. Coll
Keyword(s):  
Bone Marrow ◽  
In Situ Hybridization ◽  
Bone Marrow Transplantation ◽  
Fluorescence In Situ Hybridization ◽  
Marrow Transplantation ◽  
Allogeneic Bone Marrow Transplantation ◽  
Allogeneic Bone Marrow ◽  
Allogeneic Bone

Augmented Proliferation of Human Alveolar Macrophages After Allogeneic Bone Marrow Transplantation

Blood ◽  
1999 ◽  
Vol 93 (2) ◽  
pp. 667-673 ◽  
Author(s):  
Koh Nakata ◽  
Hajime Gotoh ◽  
Junichi Watanabe ◽  
Takeshi Uetake ◽  
Iwao Komuro ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Alveolar Macrophages ◽  
Marrow Transplantation ◽  
Allogeneic Bone Marrow Transplantation ◽  
Allogeneic Bone Marrow ◽  
Mononuclear Phagocytes ◽  
Allogeneic Bone ◽  
The Mean

After allogeneic bone marrow transplantation (allo-BMT), recipient alveolar macrophages (AM) are gradually replaced by AM of the donor origin. An influx of mononuclear phagocytes of donor origin to the lung is responsible for the repopulation, but the detailed kinetics remain unclear. We therefore studied 24 BMT recipients who underwent bronchoalveolar lavage (BAL) from 24 to 83 days after BMT. AM cell number, size, morphology, proliferating ability, and genotype of AM were measured. Before day 50, the number and size of AM in BAL fluid were similar to those of normal nonsmokers. However, after day 50, the mean number of AM increased threefold and the mean cell size decreased due to the increase of small AM. These small cells are presumably of donor origin based on DNA fingerprinting analysis and based on fluorescence in situ hybridization for the Y chromosome in a sex-mismatched case. Immunohistochemistry and cell cycle analysis demonstrated that the increase in AM number coincided with a remarkable increase of AM expressing proliferating cell nuclear antigen, suggesting that small AM are proliferating. This is the first report representing that augmented proliferation of donor AM in situ may contribute to the reconstitution of AM population after BMT.

TOLERANCE IN RENAL TRANSPLANTATION AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION???6-YEAR FOLLOW-UP

2001 ◽  
Vol 71 (11) ◽  
pp. 1681-1683 ◽  
Author(s):  
Marty T. Sellers ◽  
Mark H. Deierhoi ◽  
John J. Curtis ◽  
Robert S. Gaston ◽  
Bruce A. Julian ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Renal Transplantation ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
Allogeneic Bone Marrow Transplantation ◽  
Allogeneic Bone Marrow ◽  
Allogeneic Bone

Long-term follow-up of leukaemia patients after related cryopreserved allogeneic bone marrow transplantation

1997 ◽  
Vol 96 (2) ◽  
pp. 382-386 ◽  
Author(s):  
MARCUS STOCKSCHLADER ◽  
HASSAN T. HASSAN ◽  
CORNELIA KROG ◽  
WILLIAM KRUGER ◽  
CORNELIUS LOLIGER ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
Allogeneic Bone Marrow Transplantation ◽  
Allogeneic Bone Marrow ◽  
Allogeneic Bone ◽  
Long Term Follow Up
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