Prognostic factors for toluene diisocyanate-induced occupational asthma after removal from exposure

1997 ◽  
Vol 27 (10) ◽  
pp. 1145-1150 ◽  
Author(s):  
H.-S. PARK ◽  
D.-H. NAHM
Keyword(s):  
Prognostic Factors ◽  
Occupational Asthma ◽  
Toluene Diisocyanate

Serum ferritin and transferrin levels are not serologic markers of toluene diisocyanate–induced occupational asthma

2010 ◽  
Vol 125 (3) ◽  
pp. 762-764 ◽  
Author(s):  
Joaquín Sastre ◽  
Beatriz Sastre ◽  
Mar Fernández-Nieto ◽  
Ignacio Pérez-Camo ◽  
José Javier Sánchez ◽  
...  
Keyword(s):  
Serum Ferritin ◽  
Occupational Asthma ◽  
Toluene Diisocyanate ◽  
Serologic Markers

The HLA DRB1*1501-DQB1*0602-DPB1*0501 Haplotype Is a Risk Factor for Toluene Diisocyanate-Induced Occupational Asthma

2009 ◽  
Vol 150 (2) ◽  
pp. 156-163 ◽  
Author(s):  
Jeong-Hee Choi ◽  
Kyung-Wha Lee ◽  
Cheol-Woo Kim ◽  
Choon-Sik Park ◽  
Hyun-Young Lee ◽  
...  
Keyword(s):  
Risk Factor ◽  
Occupational Asthma ◽  
Toluene Diisocyanate

scholarly journals Practical learnings from an epidemiology study on TDI-related occupational asthma: Part I—Cumulative exposure is not a good indicator of risk

2020 ◽  
Vol 36 (11) ◽  
pp. 876-884 ◽  
Author(s):  
Patrick M Plehiers ◽  
Anne H Chappelle ◽  
Mark W Spence
Keyword(s):  
Occupational Asthma ◽  
Weighted Average ◽  
Toluene Diisocyanate ◽  
Cumulative Exposure ◽  
Respiratory Protection ◽  
Epidemiology Study ◽  
Average Value ◽  
Asthma Incidence ◽  
Anonymized Data ◽  
Epidemiology Studies

The anonymized data of an epidemiology study on incidence of toluene diisocyanate (TDI)-related occupational asthma in three US-based TDI production facilities have been reanalyzed to identify where to best focus exposure reduction efforts in industrial practice to reduce the risk of sensitization to TDI. Since the induction of sensitization has sometimes been attributed to cumulative exposure, this relationship was examined first. Gross cumulative exposure values (i.e. not taking into account whether respiratory protection was used or not) and net cumulative exposure values (i.e. accounting for the use of respiratory protection) per participant were calculated based on the duration of their study participation and the average time-weighted average value of the exposure group to which they belonged. These two sets of cumulative exposure data were compared with asthma incidence using logistic regression. Incidence was zero among workers who rarely come into contact with open plant systems (e.g. during maintenance or spills). Notwithstanding, no statistically significant relationship between asthma incidence and either gross or net cumulative exposure could be determined. This is shown to be consistent with the results of several other epidemiology studies on TDI-related occupational asthma. In conclusion, cumulative exposure values are not a good indicator of the risk of developing TDI-related occupational asthma.

scholarly journals Medical Monitoring for Occupational Asthma Among Toluene Diisocyanate Production Workers in the United States

2017 ◽  
Vol 59 ◽  
pp. S13-S21 ◽  
Author(s):  
Laura D. Cassidy ◽  
Brent Doney ◽  
Mei Lin Wang ◽  
Laura Kurth ◽  
Patrick R. Conner ◽  
...  
Keyword(s):  
United States ◽  
Occupational Asthma ◽  
The United States ◽  
Toluene Diisocyanate ◽  
Medical Monitoring

Tissue Transglutaminase Can Be Involved in Airway Inflammation of Toluene Diisocyanate-Induced Occupational Asthma

2009 ◽  
Vol 29 (6) ◽  
pp. 786-794 ◽  
Author(s):  
Gyu-Young Hur ◽  
Sung-Ho Kim ◽  
Sang Myun Park ◽  
Young-Min Ye ◽  
Cheol-Woo Kim ◽  
...  
Keyword(s):  
Airway Inflammation ◽  
Occupational Asthma ◽  
Tissue Transglutaminase ◽  
Toluene Diisocyanate

scholarly journals Role of clusterin/progranulin in toluene diisocyanate-induced occupational asthma

2018 ◽  
Vol 50 (5) ◽  
pp. 1-10 ◽  
Author(s):  
Gil-Soon Choi ◽  
Hoang Kim Tu Trinh ◽  
Eun-Mi Yang ◽  
Young-Min Ye ◽  
Yoo Seob Shin ◽  
...  
Keyword(s):  
Occupational Asthma ◽  
Toluene Diisocyanate
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