Transition from symptomless to lesional psoriatic skin

1996 ◽  
Vol 21 (5) ◽  
pp. 325-329 ◽  
Author(s):  
P.C.M. VAN DE KERKHOF ◽  
M.J.P. GERRITSEN ◽  
E.M.G.J. DE JONG
Keyword(s):  
Psoriatic Skin ◽  
Lesional Psoriatic Skin

Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin

2009 ◽  
Vol 160 (2) ◽  
pp. 319-324 ◽  
Author(s):  
C. Johansen ◽  
P.A. Usher ◽  
R.B. Kjellerup ◽  
D. Lundsgaard ◽  
L. Iversen ◽  
...  
Keyword(s):  
Psoriatic Skin ◽  
Interleukin 17 ◽  
Lesional Psoriatic Skin

scholarly journals SIRT1 activity is decreased in lesional psoriatic skin

2016 ◽  
Vol 11 (6) ◽  
pp. 891-893 ◽  
Author(s):  
Matteo Becatti ◽  
Victoria Barygina ◽  
Giacomo Emmi ◽  
Elena Silvestri ◽  
Niccolò Taddei ◽  
...  
Keyword(s):  
Psoriatic Skin ◽  
Lesional Psoriatic Skin

scholarly journals Immunity to commensal skin fungi promotes psoriasiform skin inflammation

2020 ◽  
Vol 117 (28) ◽  
pp. 16465-16474 ◽  
Author(s):  
Charlotte Hurabielle ◽  
Verena M. Link ◽  
Nicolas Bouladoux ◽  
Seong-Ji Han ◽  
Eric Dean Merrill ◽  
...  
Keyword(s):  
Steady State ◽  
Skin Inflammation ◽  
Neutrophil Extracellular Traps ◽  
Psoriatic Skin ◽  
Tissue Inflammation ◽  
Cell Responses ◽  
Extracellular Traps ◽  
Lesional Psoriatic Skin ◽  
Sense And Respond ◽  
Transcriptional Landscape

Under steady-state conditions, the immune system is poised to sense and respond to the microbiota. As such, immunity to the microbiota, including T cell responses, is expected to precede any inflammatory trigger. How this pool of preformed microbiota-specific T cells contributes to tissue pathologies remains unclear. Here, using an experimental model of psoriasis, we show that recall responses to commensal skin fungi can significantly aggravate tissue inflammation. Enhanced pathology caused by fungi preexposure depends on Th17 responses and neutrophil extracellular traps and recapitulates features of the transcriptional landscape of human lesional psoriatic skin. Together, our results propose that recall responses directed to skin fungi can directly promote skin inflammation and that exploration of tissue inflammation should be assessed in the context of recall responses to the microbiota.

Increased density of CD1a+ Langerhans cells and CD86+ cells in perilesional and lesional psoriatic skin

2017 ◽  
Vol 14 (3) ◽  
pp. 161-166
Author(s):  
Amira A. Abdel-Motaleb ◽  
Doaa S. Sayed ◽  
Hanan Morsy ◽  
Abeer E.M. Refaiy ◽  
Noha A. Abo El-Hagag ◽  
...  
Keyword(s):  
Langerhans Cells ◽  
Psoriatic Skin ◽  
Lesional Psoriatic Skin

T-Lymphocyte Clones Initiated from Lesional Psoriatic Skin Release Growth Factors that Induce Keratinocyte Proliferation

1993 ◽  
Vol 101 (5) ◽  
pp. 695-700 ◽  
Author(s):  
Poul Strange ◽  
Kevin D Cooper ◽  
Erik R Hansen ◽  
Gary Fisher ◽  
Jorgen K Larsen ◽  
...  
Keyword(s):  
Growth Factors ◽  
T Lymphocyte ◽  
Psoriatic Skin ◽  
Keratinocyte Proliferation ◽  
Lesional Psoriatic Skin

Increased Activity and Number of Epidermal Melanocytes in Lesional Psoriatic Skin

Dermatology ◽  
2016 ◽  
Vol 232 (4) ◽  
pp. 425-430 ◽  
Author(s):  
Mohamed Badawy Abdel-Naser ◽  
Aikaterini I. Liakou ◽  
Rana Elewa ◽  
Sabine Hippe ◽  
Jürgen Knolle ◽  
...  
Keyword(s):  
Psoriatic Skin ◽  
Lesional Psoriatic Skin ◽  
Increased Activity
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