scholarly journals Evaluation of amastigote reactive cells in human cutaneous leishmaniasis caused by Leishmania aethiopica

2003 ◽  
Vol 132 (2) ◽  
pp. 316-322 ◽  
Author(s):  
K. MAASHO ◽  
D. MCMAHON-PRATT ◽  
J. RAITA ◽  
M. RAUD ◽  
S. BRITTON ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Aethiopica ◽  
Human Cutaneous Leishmaniasis

The expression of TLR9 in human cutaneous leishmaniasis is associated with granuloma

2010 ◽  
Vol 32 (11-12) ◽  
pp. 769-772 ◽  
Author(s):  
F. F. TUON ◽  
E. R. FERNANDES ◽  
C. PAGLIARI ◽  
M. I. S. DUARTE ◽  
V. S. AMATO
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Human Cutaneous Leishmaniasis

scholarly journals First isolation of a new species of Leishmania responsible for human cutaneous leishmaniasis in Ghana and classification in the Leishmania enriettii complex

2015 ◽  
Vol 45 (11) ◽  
pp. 679-684 ◽  
Author(s):  
Godwin Kwakye-Nuako ◽  
Mba-Tihssommah Mosore ◽  
Christopher Duplessis ◽  
Michelle D. Bates ◽  
Naiki Puplampu ◽  
...  
Keyword(s):  
New Species ◽  
Cutaneous Leishmaniasis ◽  
Leishmania Enriettii ◽  
Human Cutaneous Leishmaniasis ◽  
A New Species

scholarly journals Cutaneous Leishmaniasis Due to Leishmania aethiopica

2018 ◽  
Vol 6 ◽  
pp. 69-81 ◽  
Author(s):  
Saskia van Henten ◽  
Wim Adriaensen ◽  
Helina Fikre ◽  
Hannah Akuffo ◽  
Ermias Diro ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Leishmania Aethiopica

scholarly journals Potential Use of Interleukin-10 Blockade as a Therapeutic Strategy in Human Cutaneous Leishmaniasis

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Lucio Roberto Castellano ◽  
Laurent Argiro ◽  
Helia Dessein ◽  
Alain Dessein ◽  
Marcos Vinícius da Silva ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Therapeutic Strategy ◽  
Interleukin 10 ◽  
Leishmania Braziliensis ◽  
Soluble Antigen ◽  
Innovative Strategies ◽  
Host Protection ◽  
Human Cutaneous Leishmaniasis ◽  
Potential Use ◽  
Worse Prognosis

Interleukin-10 overproduction has been associated with worse prognosis in human cutaneous leishmaniasis, while IFN-γ-dependent responses are associated with parasite killing and host protection. Innovative strategies are needed to overcome therapeutic failure observed in endemic areas. The use of monoclonal antibody-based immunotherapy targeting IL-10 cytokine was evaluated here. Partial IL-10 blockade inLeishmania braziliensiswhole soluble antigen-stimulated cells from endemic area CL patients with active or healed lesions and asymptomatic controls was evaluated. Overall decrease in IL-10, IL-4, and TNF-αproduction was observed in all groups of subjects. Only patients with active lesions still produced some levels of TNF-αafter anti-IL-10 stimulation in association withLeishmaniaantigens. Moreover, this strategy showed limited modulatory effects on IFN-γ-dependent chemokine CXCL10 production. Results suggest the potential immunotherapeutic use of partial IL-10 blockade in localized cutaneous leishmaniasis.

scholarly journals In situ expression of interleukin-10 and interleukin-12 in active human cutaneous leishmaniasis

1996 ◽  
Vol 15 (2-3) ◽  
pp. 101-107 ◽  
Author(s):  
Peter C. Melby ◽  
Fernando Andrade-Narvaez ◽  
Barbara J. Darnell ◽  
Guillermo Valencia-Pacheco
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Interleukin 10 ◽  
Interleukin 12 ◽  
Human Cutaneous Leishmaniasis

Matrix Remodelling and Fibroblast Phenotype in Early Lesions of Human Cutaneous Leishmaniasis

1991 ◽  
Vol 187 (8) ◽  
pp. 924-930 ◽  
Author(s):  
P. Esterre ◽  
J.P. Dedet ◽  
S. Guerret ◽  
M. Chevallier ◽  
C. Frenay ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Early Lesions ◽  
Human Cutaneous Leishmaniasis

scholarly journals Chemokines and chemokine receptors coordinate the inflammatory immune response in human cutaneous leishmaniasis

2010 ◽  
Vol 71 (12) ◽  
pp. 1220-1227 ◽  
Author(s):  
Ana P. Campanelli ◽  
Claudia I. Brodskyn ◽  
Viviane Boaventura ◽  
Claire Silva ◽  
Ana M. Roselino ◽  
...  
Keyword(s):  
Immune Response ◽  
Cutaneous Leishmaniasis ◽  
Chemokine Receptors ◽  
Inflammatory Immune Response ◽  
Human Cutaneous Leishmaniasis

Human Cutaneous Leishmaniasis Acquired in Texas *

1985 ◽  
Vol 34 (1) ◽  
pp. 58-63 ◽  
Author(s):  
Tracy L. Gustafson ◽  
Phillip G. Lawyer ◽  
Christie M. Reed ◽  
Patrick B. McGreevy ◽  
Michael G. Pappas ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Human Cutaneous Leishmaniasis
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