The natural history of the biogenic elements H, C, N, O, P and S in the cosmos is of great interest because it is these elements which comprise all life. Material ejected from stars (or pre-existing in the interstellar medium) is thought to condense into diffuse bodies of gravitationally bound gas and dust called cold interstellar molecular clouds. Current theories predict that within these clouds, at temperatures of 10-100° K, gases (primarily H2O, but including CO, CO2, CH3OH, NH3, and others) condense onto submicron silicate grains to form icy grain mantles. This interstellar ice represents the earliest and most primitive association of the biogenic elements. Within these multicomponent icy mantles, pre-biotic organic compounds are formed during exposure to UV radiation. It is thought that icy planetesimals (such as comets) within our solar system contain some pristine interstellar material, including ices, and may have (during the early bombardment of the solar system, ∼4 Ga) carried this material to Earth.Despite the widespread occurrence of astrophysical ices and their importance to pre-biotic organic evolution, few experimental data exist which address the relevant phase equilibria and possible structural states. A knowledge of the petrology of astrophysical ice analogs will allow scientists to more confidently interpret astronomical IR observations. Furthermore, the development and refinement of procedures for analyzing ices and other materials at cryogenic temperatures is critical to the study of materials returned from the proposed Rosetta comet nucleus and Mars sample return missions.
Rapid Organocatalytic Chirality Analysis of Amines, Amino Acids, Alcohols, Amino Alcohols and Diols with Achiral Iso(thio)cyanate Probes