Improved Functioning in a Woman with Schizophrenia on Exclusive Therapy with Oestrogen Pills

Objective: To highlight the therapeutic potential of oestrogen in schizophrenia and raise awareness about the need for more clinical trials. Method: Case Report. Results: The case concerns a woman suffering from chronic paranoid schizophrenia, who complied poorly with antipsychotic medication and had severely impaired psychological and social functioning. Oestrogen therapy in the form of an oral contraceptive pill (brevinor- norethisterone/ ethinyloestradiol) was used with effect. Conclusions: Oestrogen therapy shows promise in select cases in the treatment of schizophrenia and warrants further study.