‘Cornea’ provides the reader with a practical approach to the assessment and management of corneal disease. After outlining the relevant anatomy and physiology of this structure, the chapter addresses the key clinical presentations arising from corneal disease, notably infective keratitis (bacterial, viral, fungal, acanthamoeba), autoimmune keratitis, keratoconus and other ectasias, corneal degenerations, recurrent corneal erosions and persistent epithelial defects. Using a patient-centred approach the key clinical features, investigations and treatment (medical and surgical) are described for each condition. There is also extended discussion around the role of amniotic membrane transplantation and corneal transplantation including penetrating keratoplasty, and the options for both lamellar keratoplasty and endothelial keratoplasty.