Prediction of Responsiveness to an Intravenous Fluid Challenge in Patients After Cardiac Surgery With Cardiopulmonary Bypass: A Comparison Between Arterial Pulse Pressure Variation and Digital Plethysmographic Variability Index

2013 ◽  
Vol 27 (6) ◽  
pp. 1087-1093 ◽  
Author(s):  
Marc-Olivier Fischer ◽  
Arnaud Pelissier ◽  
Dan Bohadana ◽  
Jean-Louis Gérard ◽  
Jean-Luc Hanouz ◽  
...  
2021 ◽  
Vol 8 (2) ◽  
pp. 26
Author(s):  
Despoina Skouropoulou ◽  
Luca Lacitignola ◽  
Caterina Di Bella ◽  
Marzia Stabile ◽  
Claudia Acquafredda ◽  
...  

The aim of this study was to evaluate the incidence of fluid responsiveness (FR) to a fluid challenge (FC) in normotensive dogs under anaesthesia. The accuracy of pulse pressure variation (PPV), systolic pressure variation (SPV), stroke volume variation (SVV), and plethysmographic variability index (PVI) for predicting FR was also evaluated. Dogs were anaesthetised with methadone, propofol, and inhaled isoflurane in oxygen, under volume-controlled mechanical ventilation. FC was performed by the administration of 5 mL/kg of Ringer’s lactate within 5 min. Cardiac index (CI; L/min/m2), PPV, (%), SVV (%), SPV (%), and PVI (%) were registered before and after FC. Data were analysed with ANOVA and ROC tests (p < 0.05). Fluid responsiveness was defined as 15% increase in CI. Eighty dogs completed the study. Fifty (62.5%) were responders and 30 (37.5%) were nonresponders. The PPV, PVI, SPV, and SVV cut-off values (AUC, p) for discriminating responders from nonresponders were PPV >13.8% (0.979, <0.001), PVI >14% (0.956, <0.001), SPV >4.1% (0.793, <0.001), and SVV >14.7% (0.729, <0.001), respectively. Up to 62.5% of normotensive dogs under inhalant anaesthesia may be fluid responders. PPV and PVI have better diagnostic accuracy to predict FR, compared to SPV and SVV.


2008 ◽  
Vol 106 (4) ◽  
pp. 1201-1206 ◽  
Author(s):  
Jose Otavio Auler ◽  
Filomena Galas ◽  
Ludhmila Hajjar ◽  
Luciana Santos ◽  
Thiago Carvalho ◽  
...  

Shock ◽  
2008 ◽  
Vol 30 (Suppl 1) ◽  
pp. 18-22 ◽  
Author(s):  
Jose Otavio C. Auler ◽  
Filomena R.B.G. Galas ◽  
Marcia R. Sundin ◽  
Ludhmila A. Hajjar

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