Expanded Criteria Donors: Attempts to Increase the Renal Transplant Donor Pool

2000 ◽  
Vol 7 (2) ◽  
pp. 117-130 ◽  
Author(s):  
Aloke K. Mandal ◽  
Andrew N. Kalligonis ◽  
Lloyd E. Ratner
Author(s):  
E. A. Tenchurina ◽  
M. G. Minina

With the limited capacity of the available donor pool and the simultaneously growing demand for heart transplantation, expanding the heart donor selection criteria as one of the ways of increasing the availability of organ transplantation, and particularly donor heart, has become a challenge. On one hand, the use of expanded criteria donors increases the number of transplants and reduces the time spent on the waiting list. On the other hand, however, it increases the risk of adverse transplant outcomes. Accordingly, high-risk donors require a more thorough objective assessment using predictive models, while organs obtained from expanded criteria donors, require optimal selection of a donor-recipient pair. Analysis of global and national studies presented in this review reveals the depth of the current problem of heart donor selection.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Kyo Won Lee ◽  
Jae Berm Park ◽  
So Ra Cha ◽  
Seo Hee Lee ◽  
Young Jae Chung ◽  
...  

Abstract Purpose Dual kidney transplantation (DKT) offers a way to extend the use of kidneys from expanded criteria donors (ECDs). Here, we compared the outcomes of DKT with those of single kidney transplantation from standard criteria donors (SCDs) and ECDs. Methods In 2014, we began performing DKT using both kidneys from deceased donors greater than 70 years of age with one of two risk factors: serum creatinine (sCr) level over 3.0 mg/dl or eGFR under 30 ml/min. By 2017, we had performed 15 DKTs. We compared the outcomes of the 15 DKT recipients with those of 124 patients who received a kidney from an SCD and 80 patients who received a kidney from an ECD. Results Compared with ECDs and SCDs, DKT donors were older, had a higher diabetes burden, and a higher sCr level (p < 0.01, < 0.01, and 0.03, respectively). DKT recipients were also older and had a higher diabetes burden than recipients of kidneys from ECDs and SCDs (p < 0.01, both). DKT recipients had a lower nadir sCr and shorter duration to nadir sCr than single ECD KT recipients (p < 0.01and 0.04, respectively). Conclusions The survival rates of DKT grafts were compatible with those of single KT grafts. Therefore, DKT may be considered a suitable an option to expand the donor pool.


2009 ◽  
Vol 41 (8) ◽  
pp. 2970-2971 ◽  
Author(s):  
P. Domagala ◽  
A. Kwiatkowski ◽  
M. Wszola ◽  
J. Czerwinski ◽  
K. Cybula ◽  
...  

2015 ◽  
Vol 47 (1) ◽  
pp. 50-53 ◽  
Author(s):  
A. Sancho Calabuig ◽  
E. Gavela Martínez ◽  
J. Kanter Berga ◽  
S. Beltrán Calatán ◽  
A.I. Avila Bernabeu ◽  
...  

Author(s):  
M. Sh. Khubutiya ◽  
L. N. Zimina ◽  
I. E. Galankina ◽  
V. A. Gulyaev ◽  
M. S. Novruzbekov ◽  
...  

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