Synthesis of 3-Benzylphthalide Derivatives by Using a TDAE Strategy

Synlett ◽  
2020 ◽  
Author(s):  
Patrice Vanelle ◽  
Maroua Ibrahimi ◽  
Omar Khoumeri ◽  
Raoudha Abderrahim ◽  
Thierry Terme
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Benzyl Chlorides

AbstractA one-pot synthesis of new 3-benzylphthalide derivatives was developed by using a strategy based on tetrakis(dimethylamino)ethylene (TDAE). The reactions in the presence of TDAE of substituted benzyl chlorides with methyl 2-formylbenzoate or of substituted methyl-2-formylbenzoates with 4-nitrobenzyl chloride furnished the corresponding isobenzofuran-1(3H)-one products in moderate to good yields.

Nickel-Catalyzed Reductive Cross-Coupling of Benzyl Chlorides with Aryl Chlorides/Fluorides: A One-Pot Synthesis of Diarylmethanes

2016 ◽  
Vol 18 (12) ◽  
pp. 2860-2863 ◽  
Author(s):  
Jie Zhang ◽  
Gusheng Lu ◽  
Jin Xu ◽  
Hongmei Sun ◽  
Qi Shen
Keyword(s):  
Cross Coupling ◽  
One Pot ◽  
Aryl Chlorides ◽  
One Pot Synthesis ◽  
Benzyl Chlorides

S8-Mediated One-Pot Synthesis of Thioamides from Benzyl Chlorides and Amines

2016 ◽  
Vol 5 (11) ◽  
pp. 1353-1358 ◽  
Author(s):  
Xiaotong Li ◽  
Qiang Pan ◽  
Renhe Hu ◽  
Xin Wang ◽  
Zhao Yang ◽  
...  
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Benzyl Chlorides

One-Pot Synthesis and Conformational Analysis of 6-Membered Cyclic Iodonium Salts

2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim
Keyword(s):  
Conformational Analysis ◽  
Bronsted Acids ◽  
One Pot ◽  
Benzyl Alcohols ◽  
Iodonium Salts ◽  
Efficient Approach ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>

Facile and Convenient Ag/Cd/Cu Nanoparticle Catalysed One-pot Synthesis of Xanthenes

2017 ◽  
Vol 7 (12) ◽  
pp. 1192-1195
Author(s):  
Y. I. Shaikh ◽  
G. M. Nazeruddin ◽  
Khursheed Ahmed
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Cu Nanoparticle
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