Chapter 149 Malignant Minor Salivary Gland Tumors (Adenoid cystic, Mucoepidermoid, Adenocarcinoma, Low-Grade Polymorphous Adenocarcinoma)

1979 ◽  
Vol 88 (1) ◽  
pp. 112-114 ◽  
Author(s):  
Peter M. Som ◽  
Sidney S. Feuerstein ◽  
Barry D. Nagel ◽  
Lotte Strauss

Minor salivary gland tumors of the larynx are relatively rare. Morphologically the majority of them are adenoid cystic carcinomas and the overwhelming location is the subglottic larynx. Benign pleomorphic adenomas are rare minor salivary gland tumors of the larynx which usually occur at the glottic and subglottic levels. We present only the sixth case of a supraglottic benign pleomorphic adenoma that we could find in the literature. A preoperative laryngogram localized the tumor to the supraglottic larynx and the intact mucosa suggested a specific differential diagnosis. The tumor was removed by a lateral pharyngotomy with retention of good laryngeal function. The relatively asymptomatic presentation of our case is a somewhat unusual finding which, however, was previously noted in similar case reports.


2019 ◽  
Author(s):  
Sina Torabi ◽  
Todd Spock ◽  
Bruno Cardoso ◽  
Janet Chao ◽  
R. Manes ◽  
...  

1968 ◽  
Vol 25 (1) ◽  
pp. 71-86 ◽  
Author(s):  
Mario A. Luna ◽  
Paul G. Stimson ◽  
John M. Bardwil

2007 ◽  
Vol 18 (3) ◽  
pp. 192-197 ◽  
Author(s):  
Roberta Barroso Cavalcante ◽  
Fernanda Ferreira Lopes ◽  
Andréa Soares Ferreira ◽  
Roseana de Almeida Freitas ◽  
Lélia Batista de Souza

Myoepithelial cells present a complex immunophenotype, with the expression of proteins varying according to the stage of normal or neoplastic differentiation of the cell. In order to evaluate the immunohistochemical markers expressed by these cells, a panel of antibodies composed of vimentin, calponin and HHF-35 was applied to 28 salivary gland tumors. The results demonstrated a higher percent sensitivity of vimentin and calponin compared to HHF-35. However, calponin and HHF-35 presented a focal labeling pattern in contrast with the diffuse distribution of vimentin. The cells predominantly stained by all tested antibodies included nonluminal cells in duct-like and tubular structures, such as those seen in pleomorphic adenomas and adenoid cystic carcinomas, as well as cells in the cords and nests of polymorphous low-grade adenocarcinomas and peripheral cells of sheets and nests of myoepitheliomas. In conclusion, the combination of calponin and vimentin is suggested for the identification of myoepithelial cells in salivary gland tumors.


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