New Efficient Synthesis of 1,2,4-Trisubstituted Furans by a ­Sequential Passerini/Wittig/Isomerization Reaction Starting from Baylis–Hillman β-Bromo Aldehydes

Synlett ◽  
2017 ◽  
Vol 29 (01) ◽  
pp. 106-110 ◽  
Author(s):  
Ming-Wu Ding ◽  
Zhi-Lin Ren ◽  
Mei Sun ◽  
Zhi-Rong Guan
Keyword(s):  
Wittig Reaction ◽  
Isomerization Reaction ◽  
Efficient Synthesis ◽  
Trisubstituted Furans

A new and efficient synthesis of 1,2,4-trisubstituted furans from a Baylis–Hillman β-bromo aldehyde, an acid, an isocyanide, and methyl(diphenyl)phosphine, by a sequential Passerini condensation, Wittig reaction, and isomerization in the presence of triethylamine is reported.

Ultrasound-Assisted Wittig Reaction: A Short, Efficient Synthesis of 2-Methoxy-6-Alkyl-1,4-Benzoquinones

2009 ◽  
Vol 56 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Li-Qiang Wu ◽  
Chun-Guang Yang ◽  
Li-Ming Yang ◽  
Li-Juan Yang
Keyword(s):  
Wittig Reaction ◽  
Efficient Synthesis ◽  
Ultrasound Assisted

scholarly journals A Concise and Efficient Total Synthesis of α-Mangostin and β-Mangostin from Garcinia Mangostana

2013 ◽  
Vol 8 (8) ◽  
pp. 1934578X1300800
Author(s):  
Dandan Xu ◽  
Ying Nie ◽  
Xizhou Liang ◽  
Ling Ji ◽  
Songyuan Hu ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Wittig Reaction ◽  
Claisen Rearrangement ◽  
Practical Approach ◽  
Efficient Synthesis ◽  
Garcinia Mangostana ◽  
Diverse Groups

The concise, efficient synthesis of α-mangostin is described in eight simple steps with 8.3% overall yield. Highlights include a practical approach to construct the isopentene groups and other diverse groups at C–2 and C–8 of the xanthene skeleton through Claisen rearrangement and Wittig reaction. Meanwhile the first total synthesis of β-mangostin is presented with a similar approach.

Efficient synthesis of functionalized olefins by Wittig reaction using Amberlite resin as a mild base

2017 ◽  
Vol 47 (6) ◽  
pp. 581-589 ◽  
Author(s):  
Tushar R. Valkute ◽  
Eswar K. Aratikatla ◽  
Asish K. Bhattacharya
Keyword(s):  
Wittig Reaction ◽  
Efficient Synthesis

Efficient Synthesis of Thieno [2,3-d] Pyrimidin-4(4H)-ones by the Aza-Wittig Methodology

2012 ◽  
Vol 455-456 ◽  
pp. 655-659
Author(s):  
Hong Chen ◽  
Kai Yan ◽  
Ming Guo Liu
Keyword(s):  
Wittig Reaction ◽  
Catalytic Amount ◽  
Aliphatic Amines ◽  
Efficient Synthesis ◽  
Sodium Alkoxide

The carbodiimides 4, obtained from the aza-Wittig reaction of iminophosphorane 3 with aromatic isocyanates, reacted with aliphatic amines or alcohols to give 2-substituted thieno [2,3-d] pyrimidin-4(4H)-ones 6 in the presence of catalytic amount of sodium alkoxide in good yields.

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