scholarly journals Malignant Peripheral Nerve Sheath Tumor of the C2 Nerve Root: Case Report

2017 ◽  
Vol 78 (02) ◽  
pp. e68-e70
Author(s):  
Joshua Burks ◽  
Robert Briggs ◽  
Chad Glenn ◽  
John Greenert ◽  
Cordell Baker ◽  
...  

Here we present the case of a 36-year-old man who was found to have a symptomatic malignant neural sheath tumor growing from the C2 nerve root following a period of progressively worsening headaches. The patient was successfully treated with surgical resection resulting in resolution of cranial nerve deficits. Though uncommon, malignant peripheral nerve sheath tumor must be considered in the differential diagnosis of tumors involving the cervical nerve roots and carotid space.

2015 ◽  
Vol 22 (10) ◽  
pp. 1696-1699 ◽  
Author(s):  
Nolan Winslow ◽  
Kingsley Abode-Iyamah ◽  
Patricia Kirby ◽  
Mark Smith ◽  
Chandan Reddy

2016 ◽  
Vol 78 (5) ◽  
pp. 516-521
Author(s):  
Fumihisa SAWADA ◽  
Eiichi MAKINO ◽  
Takenobu YAMAMOTO ◽  
Ryo TANAKA ◽  
Yutaka FUJIWARA ◽  
...  

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii446-iii446
Author(s):  
Lacey Carter ◽  
Naina Gross ◽  
Rene McNall-Knapp ◽  
,and Jo Elle Peterson

Abstract At one month of age, a female presented with a giant congenital nevus along lower back and thighs and hydrocephalus. A ventriculoperitoneal shunt was placed. An MRI was done at six months, initially reported as normal. At eleven months of age, five months after original MRI, patient presented with dysconjugate gaze and lethargy. MRI showed new 3.8 x 3.7 x 3.4 cm right cerebellopontine angle mass extending into Meckel’s cave and foramen ovale along with leptomeningeal disease extending from the mass along the entire length of the spinal cord. Retrospective review of prior MRI revealed subtle leptomeningeal enhancement concerning for neurocutaneous melanosis (NCM). Given the leptomeningeal disease, family elected for open biopsy and debulking of lesion instead of aggressive resection. Histologically, the mass showed hypercellular spindle cell neoplasm with mitotic activity and necrosis mixed with remnants of normal cranial nerve. GFAP was negative, excluding a glioma. HMB-45, MITF, panmelanoma, and Melan-A were negative, excluding melanoma. A negative myogenin stain ruled out ectomesenchymoma. S-100 protein and SOX-10 positivity with variable loss of staining for trimethylation of histone H3 K27 were indicative of malignant peripheral nerve sheath tumor (MPNST). Given the course of the mass, trigeminal nerve MPNST was presumed. Given the poor prognosis of intracranial MPNST and NCM, family elected to forgo treatment and was discharged with hospice. She died 25 days after surgery. Cranial nerve MPNST is rare. MPNST in patients with NCM has not previously been reported to our knowledge.


2021 ◽  
Author(s):  
Miriam Magallón-Lorenz ◽  
Juana Fernández-Rodríguez ◽  
Ernest Terribas ◽  
Edgar Creus-Batchiller ◽  
Cleofe Romagosa ◽  
...  

2015 ◽  
Vol 23 (6) ◽  
pp. 505-508 ◽  
Author(s):  
Eun Young Kim ◽  
Sung Hak Lee ◽  
Han Mo Yoo ◽  
Kyo Young Song ◽  
Cho Hyun Park

Urology ◽  
2020 ◽  
Vol 135 ◽  
pp. 133-135 ◽  
Author(s):  
Hannah Agard ◽  
Neel Parekh ◽  
Curtis Clark ◽  
Eric Massanyi ◽  
Ananth Murthy ◽  
...  

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