Successful Treatment of Osgood–Schlatter Disease with Autologous-Conditioned Plasma in Two Patients

AbstractOsgood–Schlatter Disease (OSD) is a painful, growth-related overuse condition of the tibial tuberosity, leading to inflammation of the patellar ligament at the tibial tuberosity. It primarily affects young adolescents, athletic population, and usually, resolves with age or skeletal maturity. Therapy is usually conservative, with surgery indicated in a minority of cases. For patients with treatment-resistant or refractory OSD, an alternative is the application of autologous platelet concentrate. Here, we describe two cases in which autologous-conditioned plasma therapy was used to treat OSD, and present the treatment protocol developed in our clinic.

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Proximodistal and caudocranial position of the insertion of the patellar ligament on the tibial tuberosity and patellar ligament length of normal stifles and stifles with grade II medial patellar luxation in small‐breed dogs

Veterinary Surgery ◽

10.1111/vsu.13661 ◽

2021 ◽

Author(s):

Liene Feldmane ◽

Lars F. H. Theyse

Keyword(s):

Tibial Tuberosity ◽

Ligament Length ◽

Patellar Ligament ◽

Grade Ii ◽

Small Breed

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Autologous platelet concentrate in the treatment of macular holes

Der Ophthalmologe ◽

10.1007/s003470050215 ◽

1997 ◽

Vol 94 (12) ◽

pp. 877-881 ◽

Cited By ~ 3

Author(s):

F. Faude ◽

E. Edel ◽

M. Dannhauer ◽

C. Petzel ◽

P. Meier ◽

...

Keyword(s):

Platelet Concentrate ◽

Macular Holes ◽

Autologous Platelet Concentrate ◽

Autologous Platelet

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Autologous Platelet Concentrate as an Adjunct in Macular Hole Healing

Ophthalmology ◽

10.1016/s0161-6420(96)30648-9 ◽

1996 ◽

Vol 103 (4) ◽

pp. 590-594 ◽

Cited By ~ 39

Author(s):

Jean-François Korobelnik ◽

Daniele Hannouche ◽

Nacera Belayachi ◽

Michel Branger ◽

Jean-Eric Guez ◽

...

Keyword(s):

Macular Hole ◽

Platelet Concentrate ◽

Autologous Platelet Concentrate ◽

Hole Healing ◽

Autologous Platelet

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Tibial Tuberosity Transposition Fixation with a Locking Plate during Medial Patellar Luxation Surgery: An Ex Vivo Mechanical Study

Veterinary and Comparative Orthopaedics and Traumatology ◽

10.1055/s-0041-1736217 ◽

2021 ◽

Author(s):

Esa V. Eskelinen ◽

Ari P. Suhonen ◽

Juha V. Virolainen ◽

William D. Liska

Keyword(s):

Phase I ◽

Phase Ii ◽

Locking Plate ◽

Ex Vivo ◽

Tibial Tuberosity ◽

Tension Band ◽

Patellar Ligament ◽

Raccoon Dog ◽

Tension Band Wire ◽

Lower Load

Abstract Objectives The purpose of this study was to compare the load at failure, stiffness and mode of failure between three types of tibial tuberosity transposition fixation techniques: (a) pin and figure-8 tension band wire (Pin-TBW), (b) locking plate with pin and a tension band wire (Plate-Pin-TBW) and (c) locking plate with a pin (Plate-Pin). Methods Six pairs of raccoon dog cadaveric tibiae were tested in Phase I Pin-TBW versus Plate-Pin-TBW and seven pairs in Phase II Plate-Pin-TBW versus Plate-Pin. One limb of each pair was randomly assigned to one of two groups for each phase. A tensile force was applied to the patellar ligament until construct failure. Results Pin-TBW (342N ± 54.7N) failed at a lower load than Plate-Pin-TBW (469N ± 77.3N), p = 0.00748, with all Pin-TBW failing by fracture and the majority of Plate-Pin-TBW failing by rupture of patellar ligament. Pin-TBW group Phase I, normalized with Plate-Pin-TBW Phase I, failed at a lower load than Plate-Pin group Phase II, normalized with Plate-Pin-TBW Phase II, p = 0.00467. There was no significant difference in mean load at failure, stiffness or mode at failure between the groups in the Phase II study. Clinical Significance Although ex vivo mechanical testing does not replicate the postoperative live dog or cat, these results demonstrate lower construct strength of the Pin-TBW construct compared with the Plate-Pin construct in the raccoon dog cadaver model.

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Is autologous platelet concentrate beneficial for post-extraction socket healing? A systematic review

International Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.ijom.2011.04.009 ◽

2011 ◽

Vol 40 (9) ◽

pp. 891-900 ◽

Cited By ~ 44

Author(s):

M. Del Fabbro ◽

M. Bortolin ◽

S. Taschieri

Keyword(s):

Systematic Review ◽

Platelet Concentrate ◽

Extraction Socket ◽

Autologous Platelet Concentrate ◽

Socket Healing ◽

Autologous Platelet

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Successful Management of Treatment-Resistant Alopecia Areata with Platelet Rich Plasma: A Case Series

Serbian Journal of Dermatology and Venerology ◽

10.2478/sjdv-2019-0007 ◽

2019 ◽

Vol 11 (2) ◽

pp. 50-52

Author(s):

Sanjeewani Fonseka ◽

Y.M.D.M Bandara ◽

Brabaharan Subhani

Keyword(s):

Alopecia Areata ◽

Platelet Rich Plasma ◽

Case Reports ◽

Immunosuppressive Agents ◽

Case Series ◽

Treatment Resistant ◽

Successful Management ◽

Autologous Platelet Rich Plasma ◽

Dermal Injection ◽

Autologous Platelet

Abstract Introduction. Alopecia areata (AA) is an autoimmune disease-causing non-scarring alopecia. It is usually treated with immunosuppressive agents, to which some patients fail to respond adequately. Material and Methods. Three patients with AA refractory to standard therapy were treated with intra-dermal injection of autologous platelet rich plasma (PRP) every four weeks. Results. All three patients showed remarkable improvement after multiple sessions of PRP treatment. Conclusion. Autologous PRP is safe and effective in treatment-resistant forms of AA demonstrated in many case reports; therefore it deserves further study with randomized, placebo-controlled trials.

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Tibial Plateau Leveling Following Tibial Tuberosity Advancement: A Case Series

Veterinary Sciences ◽

10.3390/vetsci9010016 ◽

2022 ◽

Vol 9 (1) ◽

pp. 16

Author(s):

Daniele Serrani ◽

Pierre Paul Picavet ◽

Juan Marti ◽

Bernard Bouvy ◽

Marc Balligand ◽

...

Keyword(s):

Tibial Plateau ◽

Case Series ◽

Major Complication ◽

Tibial Tuberosity ◽

Patellar Ligament ◽

Short Term ◽

Long Term Follow Up ◽

Persistent Instability

Persistent stifle instability is a recognized complication following tibial tuberosity advancement techniques (TTAT). The aim of this study is to report the feasibility and outcome of tibial plateau leveling techniques (TPLT) to treat dogs with persistent lameness, suspected to be secondary to persistent stifle instability, following (TTAT). Medical records of dogs presented for persistent lameness after TTAT were reviewed. Preoperative data included orthopedic examination, lameness score and radiographs. Inclusion criteria included performance of a surgery to address persistent lameness and suspected instability. Short-term follow up data included orthopedic examination and radiographs of the stifle. Long-term follow up was based on postoperative Liverpool Osteoarthritis in Dogs (LOAD) questionnaire. Seven dogs were included in the study. Mean subjective preoperative lameness score was 3 ± 1.53. Mean preoperative patellar ligament angle relative to the tibial plateau (PLATP) was 94° and mean tibial plateau angle (TPA) was 28°. Six dogs had tibial plateau leveling osteotomy and one had modified cranial closing wedge ostectomy. Mean postoperative PLATP was 79° and mean TPA was 5°. Mean subjective lameness score at follow up was 0.57 ± 0.49. Minor complications were present in 2 dogs and major complication in 1 dog. Mean LOAD questionnaire score was 6.6/52. TPLT can be performed after TTAT and may improve clinical function and stability in these cases in which persistent instability is suspected.

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