Low Dose Heparin in the Prevention of Deep-Vein Thrombosis after Aortic Bifurcation Graft Surgery
1979 ◽
Vol 42
(05)
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pp. 1429-1433
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Keyword(s):
Low Dose
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SummaryAn optimal inhibition of tissue fibrinolysis, studied by a histochemical fibrin slide technique in the rat stomach, was obtained by administration of tranexamic acid in a dose of 60 mg/100 g body weight. A significant fibrinolysis inhibition was found within 5 min, when tranexamic acid in this dose was given either intravenously or intragastrically. A prolonged duration of fibrinolysis inhibition was observed after intragastric administration. After 4 hr no inhibitory effect of tranexamic acid could be recorded, irrespective of the route of administration.