A Simple Method for the Conversion of Adamantyl, Benzyl and Benzyhydryl Alcohols to Their Corresponding Bromides and Chlorides and the Transhalogenation of Adamantyl, Benzyl, Benzhydryl and Tertiary Alkyl Bromides and Chlorides

Synthesis ◽  
1989 ◽  
Vol 1989 (08) ◽  
pp. 614-616 ◽  
Author(s):  
A. Amrollah-Madjdabadi ◽  
Tung N. Pham ◽  
E. C. Ashby
Keyword(s):  
Simple Method ◽  
Alkyl Bromides ◽  
Tertiary Alkyl

Zn- and Cu-Catalyzed Coupling of Tertiary Alkyl Bromides and Oxalates to Forge Challenging C–O, C–S, and C–N Bonds

2021 ◽  
Vol 23 (3) ◽  
pp. 1005-1010
Author(s):  
Yuxin Gong ◽  
Zhaodong Zhu ◽  
Qun Qian ◽  
Weiqi Tong ◽  
Hegui Gong
Keyword(s):  
Alkyl Bromides ◽  
Tertiary Alkyl

ChemInform Abstract: Silver-Catalyzed Benzylation and Allylation of Tertiary Alkyl Bromides with Organozinc Reagents.

ChemInform ◽  
2010 ◽  
Vol 41 (42) ◽  
Author(s):  
Yukihiro Mitamura ◽  
Yoshihiro Asada ◽  
Kei Murakami ◽  
Hidenori Someya ◽  
Hideki Yorimitsu ◽  
...  
Keyword(s):  
Alkyl Bromides ◽  
Organozinc Reagents ◽  
Tertiary Alkyl

scholarly journals Copper-catalyzed direct alkylation of heteroarenes

2017 ◽  
Vol 8 (5) ◽  
pp. 3465-3470 ◽  
Author(s):  
Cédric Theunissen ◽  
Jianjun Wang ◽  
Gwilherm Evano
Keyword(s):  
Alkyl Radicals ◽  
Alkyl Bromides ◽  
Tertiary Alkyl

An efficient and broadly applicable process is reported for the direct alkylation of heteroarene C–H bonds, based on the copper-catalyzed addition of alkyl radicals generated from activated secondary and tertiary alkyl bromides to a range of arenes, and their benzo-fused derivatives.

Synthèse de cétones encombrées via réduction de nitriles tertiaires en présence de métaux alcalins

1978 ◽  
Vol 56 (21) ◽  
pp. 2731-2736 ◽  
Author(s):  
Jean-Paul Mazaleyrat
Keyword(s):  
Radical Anion ◽  
Alkali Metals ◽  
Simple Method ◽  
Hydrolysis Of ◽  
Tertiary Alkyl

The reaction of alkali metals with tertiary alkyl nitriles eventually gives, after protonation, an imine. α-tert-Alkylketones are produced by the hydrolysis of these imines. This reaction, involving radical anion intermediates, is a simple method for the synthesis of highly hindered symmetric ketones.

A Direct Functionalization of Tertiary Alkyl Bromides with O-, N-, and C-Nucleophiles.

ChemInform ◽  
2007 ◽  
Vol 38 (46) ◽  
Author(s):  
Petr Vachal ◽  
Joan M. Fletcher ◽  
William K. Hagmann
Keyword(s):  
Alkyl Bromides ◽  
Direct Functionalization ◽  
Tertiary Alkyl

Irradiation-Induced Palladium-Catalyzed Direct C–H Alkylation of Heteroarenes with Tertiary and Secondary Alkyl Bromides

Synthesis ◽  
2018 ◽  
Vol 50 (15) ◽  
pp. 2908-2914 ◽  
Author(s):  
Rui Shang ◽  
Yao Fu ◽  
Guang-Zu Wang
Keyword(s):  
Blue Light ◽  
Palladium Catalyst ◽  
Light Emitting Diodes ◽  
Oxidative Addition ◽  
Phosphine Ligands ◽  
Light Emitting ◽  
Alkyl Radicals ◽  
Alkyl Bromides ◽  
Palladium Catalyzed ◽  
Tertiary Alkyl

A palladium catalyst in combination with two types of phosphine ligands efficiently catalyzes direct C–H alkylation of heteroarenes with secondary and tertiary alkyl bromides under irradiation conditions. Irradiation of blue light-emitting diodes (blue LEDs) effectively excites phosphine-ligated palladium catalyst to facilitate oxidative addition with alkyl bromides, and also excites the alkylpalladium species to enable the generation of alkyl radicals to react with heteroarenes.

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