Recombinant immunoblot for assessment of intrathecally synthesised paraneoplastic antineuronal antibodies in cerebrospinal fluid from patients with paraneoplastic neurological syndromes

2007 ◽  
Vol 34 (S 2) ◽  
Author(s):  
O Stich ◽  
S Jarius ◽  
C Rasiah ◽  
R Voltz ◽  
S Rauer
Keyword(s):  
Cerebrospinal Fluid ◽  
Paraneoplastic Neurological Syndromes ◽  
Antineuronal Antibodies

scholarly journals Absence of cerebrospinal fluid antineuronal antibodies in schizophrenia spectrum disorders

2018 ◽  
Vol 212 (5) ◽  
pp. 318-320 ◽  
Author(s):  
Tatiana Oviedo-Salcedo ◽  
Lot de Witte ◽  
Tania Kümpfel ◽  
René S. Kahn ◽  
Peter Falkai ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Clinical Signs ◽  
Autoimmune Encephalitis ◽  
Schizophrenia Spectrum Disorders ◽  
Serum Antibodies ◽  
Serum Samples ◽  
Antineuronal Antibodies ◽  
Schizophrenia Spectrum ◽  
Positive Serum ◽  
Spectrum Disorders

SummaryAntibody-mediated encephalitis has been discussed as one possible cause for isolated psychotic syndromes. Mostly based on serum samples, findings have been controversial. We present the results of a retrospective study of 124 clinically diagnosed psychotic patients without documented relevant neurological symptoms. All were tested for different antineuronal antibodies in cerebrospinal fluid (CSF) while 81 received serum testing. Antineuronal antibodies in CSF were negative across the sample. 3.7% showed low positive serum antibodies. Our findings highlight the importance of a deeper discussion about the relevance of low positive serum antibodies without concurrent findings in CSF or clinical signs for autoimmune encephalitis.Declaration of interestNone.

Specific antibody index in cerebrospinal fluid from patients with central and peripheral paraneoplastic neurological syndromes

2007 ◽  
Vol 183 (1-2) ◽  
pp. 220-224 ◽  
Author(s):  
Oliver Stich ◽  
Sven Jarius ◽  
Barbara Kleer ◽  
Christiane Rasiah ◽  
Raymond Voltz ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Specific Antibody ◽  
Antibody Index ◽  
Paraneoplastic Neurological Syndromes

No evidence for the presence of HuD-specific T cells in the cerebrospinal fluid of patients with Huassociated paraneoplastic neurological syndromes

2009 ◽  
Vol 256 (2) ◽  
pp. 279-282 ◽  
Author(s):  
J. W. Beukelaar ◽  
J. C. Milikan ◽  
G. M. Verjans ◽  
M. T. Graaf ◽  
Y. Norden ◽  
...  
Keyword(s):  
T Cells ◽  
Cerebrospinal Fluid ◽  
Paraneoplastic Neurological Syndromes
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