An extraordinary Dieulafoy's lesion presenting as varices of the gastric fundus

2001 ◽  
Vol 54 (6) ◽  
pp. 776-779 ◽  
Author(s):  
Thorsten Pohle ◽  
Martin Helleberg ◽  
Josef Menzel ◽  
Raihanatou Diallo ◽  
Thomas Vestring ◽  
...  
2021 ◽  
Author(s):  
Boheng Liu ◽  
Yanzhao Xu ◽  
Chunyue Gai ◽  
Anran Qie ◽  
Ziqiang Tian

Abstract Background: Dieulafoy’s lesion is a dilated, aberrant, submucosal vessel that erodes the overlying epithelium without obvious ulceration. Dieulafoy's lesion is a rare disease, meanwhile the lesion secondary to resection of lung cancer is even extremely rare. It is most commonly located in the lesser curvature of the stomach but rarely occurrences in extragastric sites have also been reported. To summarize the key points in the diagnosis and treatments of this disease, we present a clinical case of acute gastrointestinal bleeding due to Dieulafoy's lesion in the gaster secondary to resection of lung cancer.Case presentation: An 58-year-old woman presented with a clinical condition of haematemesis and haematochezia associated with anaemia and haemodynamic instability, needing blood transfusion. After many changes of body position, when the patient was in prone position, we finally found jet bleeding on the gastric body near the great curvature of gastric fundus under gastroscopy, and then we performed successfully with hemostatic clip placement. Hospitalization occurred without further com plications. There was no recurrence after 18 months follow-up.Conclusion: It is essential to be aware of this lesion as a possible cause of gastrointestinal bleeding and especially thoracic postoperative acute gastrointestinal appears. Timely and effective endoscopy can improve the diagnosis rate of these lesions and reduce the related mortality. At the same time, we need to pay attention to the patients with the risk factors in the perioperative period to reduce the incidence of Dieulafoy's lesion.


2007 ◽  
Vol 79 (9) ◽  
Author(s):  
Stanisław Przywara ◽  
Grzegorz Wallner ◽  
Andrzej Dąbrowski ◽  
Tomasz Skoczylas ◽  
Jacek Wroński ◽  
...  
Keyword(s):  

2008 ◽  
Vol 24 (1) ◽  
pp. 58
Author(s):  
Gyoo Moon ◽  
Jong Beom Park ◽  
Hee Chul Chang ◽  
Chang Huh ◽  
Chang Hee Paik ◽  
...  

Author(s):  
Qazi Shahbaz Ahmad ◽  
Omair Ashraf Shah ◽  
Gowhar Nazir ◽  
Faiz Altaf Shera ◽  
Asif muzaffer reshi ◽  
...  
Keyword(s):  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guiqin Chen ◽  
Lei Nie ◽  
Tijiang Zhang

Abstract Background The accessory spleen has no anatomical or vascular relationship with the normal spleen, The tissue structure and physiological function of the accessory spleen are the same as those of the normal spleen, which usually locate in the splenic hilum and the tail of the pancreas. The aims of this manuscript are to present a rare case of the gastric accessory spleen and a review of the literature. Case presentation A 19-year-old male patient was sent to the emergency department with stomach bleeding after drinking alcohol. The computed tomographic scan showed a 1.2 cm × 1.7 cm mass at the lesser curvature of the gastric fundus. Gastrointestinal endoscopy displayed a submucosal elevated lesion on the gastric fundus, and gastrectomy was performed. Postoperative pathological examination proved an accessory spleen in the stomach. The postoperative course was uneventful, and the patient was discharged on the 6th day after the surgery. Conclusions The accessory spleen at the fundus of stomach is extremely rare, especially in this case, which is accompanied by acute gastric bleeding, and it is difficult to diagnosis before operation. Many literatures reported that it was misdiagnosis as tumor, so it is necessary to diagnose accessory spleen correctly.


1996 ◽  
Vol 270 (6) ◽  
pp. G897-G901 ◽  
Author(s):  
J. DelValle ◽  
J. Wakasugi ◽  
H. Takeda ◽  
T. Yamada

The Ca2+/inositol phospholipid signaling cascade has been implicated in the mechanism by which cholecystokinin (CCK) stimulates gastric somatostatin release, but a direct linkage between intracellular events in gastric D cells and somatostatin secretion has not been established. To address this problem we developed a method for correlating somatostatin release with the measurement of intracellular Ca2+ concentration ([Ca2+]i) in isolated D cells. Resting [Ca2+]i in single D cells was 100 +/- 5.7 nM (means +/- SE, n = 41), and CCK induced a rise in [Ca2+]i in a dose-dependent fashion, producing a maximal stimulatory effect (243 +/- 15% of control, n = 12) at a peptide concentration of 2 x 10(-8) M. The CCK-mediated increase in [Ca2+]i was biphasic, with a rapid, initial transient elevation followed by a sustained plateau. The rise in [Ca2+]i was accompanied by a concomitant increase in release of somatostatin-like immunoreactivity (SLI). Removal of extracellular Ca2+ had no effect on the initial transient elevation in [Ca2+]i induced by CCK but abolished both the sustained plateau in [Ca2+]i and the release of SLI. The selective CCK antagonist L-364, 718 (10(-7) M) inhibited the effects of CCK on both [Ca2+]i and SLI release. The nonspecific Ca2+ channel blocker NiCl2 (10(-3) M) and the L-type Ca2+ channel blocker nifedipine inhibited the sustained rise in [Ca2+]i and the release of SLI but left the initial transient increase in [Ca2+]i unaltered. These results indicate that CCK-stimulated release of SLI from D cells in the gastric fundus is linked to influx of extracellular Ca2+ via L-type Ca2+ channels.


2000 ◽  
Vol 131 (4) ◽  
pp. 745-755 ◽  
Author(s):  
Yuji Okada ◽  
Akiyoshi Hara ◽  
Hong Ma ◽  
Chun-Yang Xiao ◽  
Osamu Takahata ◽  
...  

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