Function of the Eustachian Tube After Weekly Exposure to Pepsin/Hydrochloric Acid

2001 ◽  
Vol 125 (3) ◽  
pp. 123-129 ◽  
Author(s):  
S. Brett Heavner ◽  
Stuart M. Hardy ◽  
David R. White ◽  
Chapman T. McQueen ◽  
Jiri Prazma ◽  
...  
Keyword(s):  
Hydrochloric Acid ◽  
Eustachian Tube ◽  
Weekly Exposure

Transient Inflammation and Dysfunction of the Eustachian Tube Secondary to Multiple Exposures of Simulated Gastroesophageal Refluxant

2001 ◽  
Vol 110 (10) ◽  
pp. 928-934 ◽  
Author(s):  
S. Brett Heavner ◽  
Stuart M. Hardy ◽  
Jiri Prazma ◽  
David R. White ◽  
Harold C. Pillsbury
Keyword(s):  
Hydrochloric Acid ◽  
Gastroesophageal Reflux ◽  
Eustachian Tube ◽  
Middle Ear ◽  
Negative Pressure ◽  
Saline Solution ◽  
Otitis Media With Effusion ◽  
Eustachian Tube Dysfunction ◽  
Tube Dysfunction ◽  
Phosphate Buffered Saline

Gastroesophageal reflux is a common problem in the newborn and preschool periods. Recent research suggests that it may be related to eustachian tube dysfunction and otitis media with effusion. The purpose of this experiment was to investigate the relationship between simulated gastroesophageal reflux and eustachian tube dysfunction. Rat middle ears were repeatedly exposed (transtympanically) to pepsin in hydrochloric acid or to phosphate-buffered saline solution. Their eustachian tube function was evaluated by assessing passive opening and passive closing pressures, and active clearance of positive and negative pressure. The passive pressure function tests showed variable results. The rats exposed to pepsin in hydrochloric acid had an impaired ability to clear positive and negative pressure from the middle ear as compared to the rats exposed only to phosphate-buffered saline solution. The results demonstrate that multiple middle ear exposures to pepsin in hydrochloric acid leads to eustachian tube dysfunction in rats.

Fine Structure of Platelet Interaction with a New Microcrystalline Collagen Preparation

1974 ◽  
Vol 32 ◽  
pp. 58-59
Author(s):  
W. H. Zucker ◽  
R. G. Mason
Keyword(s):  
Fine Structure ◽  
Platelet Aggregation ◽  
Hydrochloric Acid ◽  
Whole Blood ◽  
Platelet Adhesion ◽  
Hemostatic Agent ◽  
Native Collagen ◽  
Fibrillar Morphology ◽  
Clinical Interest ◽  
New Form

Platelet adhesion initiates platelet aggregation and is an important component of the hemostatic process. Since the development of a new form of collagen as a topical hemostatic agent is of both basic and clinical interest, an ultrastructural and hematologic study of the interaction of platelets with the microcrystalline collagen preparation was undertaken.In this study, whole blood anticoagulated with EDTA was used in order to inhibit aggregation and permit study of platelet adhesion to collagen as an isolated event. The microcrystalline collagen was prepared from bovine dermal corium; milling was with sharp blades. The preparation consists of partial hydrochloric acid amine collagen salts and retains much of the fibrillar morphology of native collagen.

Endoscopic Transnasal Eustachian Tube Closure using the V-LOC Wound Closure Device

2020 ◽  
Author(s):  
Andrew J. Thomas ◽  
Sachin Gupta ◽  
Aclan Dogan ◽  
Timothy L. Smith ◽  
Justin Cetas ◽  
...  
Keyword(s):  
Eustachian Tube ◽  
Wound Closure ◽  
Closure Device ◽  
Tube Closure

Extended Transpterygoid Endonasal Far Lateral Approach: The Role of the Eustachian Tube Revised

Skull Base ◽  
2009 ◽  
Vol 19 (01) ◽  
Author(s):  
Paolo Battaglia ◽  
Guglielmo Romano ◽  
Iacopo Dallan ◽  
Maurizio Bignami ◽  
Luca Muscatello ◽  
...  
Keyword(s):  
Eustachian Tube ◽  
Lateral Approach ◽  
Far Lateral Approach ◽  
Far Lateral

Persistant dysfunction of the eustachian tube: solving the problem

2019 ◽  
Vol 27 (Special Issue) ◽  
Author(s):  
Kryukov A. I. ◽  
◽  
Kunelskaya N. L. ◽  
Tsarapkin G. Yu. ◽  
Garov E. V. ◽  
...  
Keyword(s):  
Eustachian Tube
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