A Facile and Efficient Synthesis of Functionalized γ-Butyrolactones from Baylis - Hillman Adducts of Isatin

A facile and efficient stereoselective synthesis of functionalized substituted γ-butyrolactones in excellent yield from the Baylis–Hillman adducts of isatin derivatives by a reductive cyclization methodology is reported.

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Efficient synthesis of tetrahydrofurans with chiral tertiary allylic alcohols catalyzed by Ni/P-chiral ligand DI-BIDIME

Catalysis Science & Technology ◽

10.1039/d0cy02470h ◽

2021 ◽

Author(s):

Yu Mu ◽

Tao Zhang ◽

Yaping Cheng ◽

Wenzhen Fu ◽

Zuting Wei ◽

...

Keyword(s):

Reductive Cyclization ◽

Allylic Alcohols ◽

Chiral Ligand ◽

Efficient Synthesis

Efficient nickel-catalyzed stereoselective asymmetric intramolecular reductive cyclization of O-alkynones with P-chiral bisphosphorus ligand DI-BIDIME is reported.

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Straightforward Strategy for the Stereoselective Synthesis of Spiro-Fused (C-5)Isoxazolino- or (C-3)Pyrazolino-(C-3)quinolin-2-ones from Baylis-Hillman Adducts by 1,3-Dipolar Cycloaddition and Reductive Cyclization

European Journal of Organic Chemistry ◽

10.1002/ejoc.200800746 ◽

2008 ◽

Vol 2008 (32) ◽

pp. 5446-5460 ◽

Cited By ~ 23

Author(s):

Virender Singh ◽

Vijay Singh ◽

Sanjay Batra

Keyword(s):

Stereoselective Synthesis ◽

Reductive Cyclization ◽

Dipolar Cycloaddition

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Catalyst‐Free Efficient Synthesis of Alkyl Acetates Bearing Arylsulfide and Quinoxaline Moieties and Stereoselective Synthesis of Dialkyl 2‐Amino‐3‐thiomalates at Room Temperature

ChemistrySelect ◽

10.1002/slct.201901287 ◽

2019 ◽

Vol 4 (41) ◽

pp. 11995-12001 ◽

Cited By ~ 1

Author(s):

Sayyed Abolghasem Hashemi ◽

Mohammad Reza Mohammadizadeh

Keyword(s):

Room Temperature ◽

Stereoselective Synthesis ◽

Efficient Synthesis ◽

Catalyst Free ◽

Alkyl Acetates

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Efficient synthesis of α-alkyl-β-amino amides by transaminase-mediated dynamic kinetic resolutions

Catalysis Science & Technology ◽

10.1039/c9cy01004a ◽

2019 ◽

Vol 9 (15) ◽

pp. 4083-4090 ◽

Cited By ~ 2

Author(s):

Ángela Mourelle-Insua ◽

Daniel Méndez-Sánchez ◽

James L. Galman ◽

Iustina Slabu ◽

Nicholas J. Turner ◽

...

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Efficient Synthesis ◽

Dynamic Kinetic Resolution ◽

Amino Amides ◽

Kinetic Resolutions

A transaminase-catalyzed dynamic kinetic resolution is described for the stereoselective synthesis of a series of α-alkyl-β-amino amides.

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ChemInform Abstract: Straightforward Strategy for the Stereoselective Synthesis of Spiro-Fused (C-5)Isoxazolino- or (C-3)Pyrazolino-(C-3)quinolin-2-ones from Baylis-Hillman Adducts by 1,3-Dipolar Cycloaddition and Reductive Cyclization.

ChemInform ◽

10.1002/chin.200911152 ◽

2009 ◽

Vol 40 (11) ◽

Author(s):

Virender Singh ◽

Vijay Singh ◽

Sanjay Batra

Keyword(s):

Stereoselective Synthesis ◽

Reductive Cyclization ◽

Dipolar Cycloaddition

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Unexpected isocyanide-based three-component bicyclization for the stereoselective synthesis of densely functionalized pyrano[3,4-c]pyrroles

Chemical Communications ◽

10.1039/c5cc08071a ◽

2016 ◽

Vol 52 (5) ◽

pp. 900-903 ◽

Cited By ~ 44

Author(s):

Qian Gao ◽

Wen-Juan Hao ◽

Feng Liu ◽

Shu-Jiang Tu ◽

Shu-Liang Wang ◽

...

Keyword(s):

Stereoselective Synthesis ◽

Efficient Synthesis ◽

Dialkyl Acetylenedicarboxylates

A novel three-component bicyclization strategy for the efficient synthesis of densely functionalized pyrano[3,4-c]pyrroles has been established from readily accessible 3-aroylacrylic acids, dialkyl acetylenedicarboxylates and isocyanides.

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Water-Mediated Green and Efficient Synthesis of Bis(Indolyl)methanes Using Ammonium Iron(II) Sulfate

Letters in Organic Chemistry ◽

10.2174/1570178616666190522121135 ◽

2019 ◽

Vol 17 (1) ◽

pp. 61-67 ◽

Cited By ~ 1

Author(s):

Vikas D. Kadu ◽

Dinesh N. Nadimetla ◽

Mahesh G. Hublikar ◽

Dattatraya G. Raut ◽

Raghunath B. Bhosale

Keyword(s):

Green Water ◽

Efficient Synthesis ◽

Excellent Yield ◽

Water Solvent ◽

Ammonium Iron

An efficient protocol for the synthesis of symmetrical 3,3’-bis(indolyl)arylmethanes catalyzed by green and easily available ammonium iron(II) sulfate (Mohr’s salt) has been developed in “green” water solvent afforded in excellent yield.

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Synthesis of Trans-6-(4-Chlorobenzoyl)-7-(Aryl)-1,3-Dimethyl-6,7-Dihydrofuro[3,2-d]Pyrimidine-2,4-Diones Using Choline Hydroxide as an Efficient Catalyst in an Aqueous Medium

Journal of Chemical Research ◽

10.3184/174751917x14859570937794 ◽

2017 ◽

Vol 41 (3) ◽

pp. 139-142 ◽

Cited By ~ 3

Author(s):

Maryam Salari ◽

Alireza Hassanabadi ◽

Mohammad H. Mosslemin

Keyword(s):

Aqueous Medium ◽

Aromatic Aldehyde ◽

Reaction Times ◽

Efficient Synthesis ◽

One Pot ◽

Efficient Catalyst ◽

Excellent Yield ◽

One Pot Condensation

A green and efficient synthesis of the trans-6-(4-chlorobenzoyl)-7-(aryl)-1,3-dimethyl-6,7-dihydrofuro[3,2-d]pyrimidine-2,4-diones has been achieved via a three-component, one-pot condensation of 2-[2-(4-chlorophenyl)-2-oxoethyl)]isoquinolinium bromide with 1,3-dimethylbarbituric acid and an aromatic aldehyde in the presence of catalytic amounts of choline hydroxide in water under reflux conditions. This gives trans-6-(4-chlorobenzoyl)-7-(aryl)-1,3-dimethyl-6,7-dihydrofuro[3,2-d]pyrimidine-2,4-diones in excellent yield and in short reaction times.

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