A case of gonococcal necrotising fasciitis

Sexual Health ◽  
2014 ◽  
Vol 11 (3) ◽  
pp. 280
Author(s):  
Kudzai Nzenza Kanhutu ◽  
Denis D. Spelman ◽  
Michael D. Weymouth

This case report details the progress of a patient with severe disseminated gonococcal infection with associated necrotising fasciitis. His admission was punctuated by multiple surgical debridements and a prolonged intensive care stay due to multiple organ failure. An extended course of azithromycin-based antimicrobial therapy achieved a cure and the patient was eventually discharged home after 8 weeks. To our knowledge this is the first such case of histologically and microbiologically confirmed gonococcal necrotising fasciitis.

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 79
Author(s):  
Dino Mijatovic ◽  
Ana Blagaic ◽  
Zeljko Zupan

Introduction: Hemolytic-uremic syndrome (HUS) is a leading cause of acute renal failure in infants and young children. It is traditionally defined as a triad of acute renal failure, hemolytic anemia and thrombocytopenia that occur within a week after prodromal hemorrhagic enterocolitis. Severe cases can also be presented by acute respiratory distress syndrome (ARDS), toxic megacolon with ileus, pancreatitis, central nervous system (CNS) disorders and multiple organ failure (MOF).Case presentation: A previously healthy 4-year old Caucasian girl developed acute renal failure, thrombocytopenia and hemolytic anemia following a short episode of abdominal pain and bloody diarrhea. By the end of the first week the diagnosis of the typical HUS was established. During the second week the disease progressed into MOF that included ileus, pancreatitis, hepatitis, coma and ARDS, accompanied by hemodynamic instability and extreme leukocytosis. Nonetheless, the girl made a complete recovery after one month of the disease. She was successfully treated in the intensive care unit and significant improvement was noticed after plasmapheresis and continuous veno-venous hemodialysis.Conclusions: Early start of plasmapheresis and meticulous supportive treatment in the intensive care unit, including renal placement therapy, may be the therapy of choice in severe cases of HUS presented by MOF. Monitoring of prognostic factors is important for early performance of appropriate diagnostic and therapeutical interventions.


2021 ◽  
Vol 50 (2) ◽  
pp. 86-90
Author(s):  
Wataru Kato ◽  
Yuki Goto ◽  
Ryota Yamamoto ◽  
Tsubasa Yazawa ◽  
Sho Akita ◽  
...  

2019 ◽  
Author(s):  
ANURADHA NITTUR ◽  
Rajesh Srivastava

The case report has been presented to demonstrate the response to Pranic Healing intervention by a patient with Acute Respiratory Distress Syndrome (ARDS), heading towards multiple organ failure, triggered by secondary haemophagocyticlymphohistiocytosis (HLH)The29 yr old patient had been on ventilator support, immunocompromised and in a critical state with multiple diagnosis and multiple hospitalizations for nearly eight months. He had stopped responding to conventional medicine and acupuncture. Complimentary Therapy in the form of Pranic Healing, a no touch, no drug energy therapy was provided to the patient for three months. Pranic Healing along with standardised medical care helped the patient recover rapidly and he was discharged within six weeks of starting Pranic Healing therapy. The case study provides a promising example of Pranic Healing intervention in averting multiple organ failure and promoting regeneration of vital organs.


2005 ◽  
Vol 9 (5) ◽  
pp. 423-428 ◽  
Author(s):  
Shu Wakino ◽  
Shingo Hori ◽  
Takuya Mimura ◽  
Seitaroh Fujishima ◽  
Koichi Hayashi ◽  
...  

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 79
Author(s):  
Dino Mijatovic ◽  
Ana Blagaic ◽  
Zeljko Zupan

Introduction: Hemolytic-uremic syndrome (HUS) is a leading cause of acute renal failure in infants and young children. It is traditionally defined as a triad of acute renal failure, hemolytic anemia and thrombocytopenia that occur within a week after prodromal hemorrhagic enterocolitis. Severe cases can also be presented by acute respiratory distress syndrome (ARDS), toxic megacolon with ileus, pancreatitis, central nervous system (CNS) disorders and multiple organ failure (MOF).Case presentation: A previously healthy 4-year old Caucasian girl developed acute renal failure, thrombocytopenia and hemolytic anemia following a short episode of abdominal pain and bloody diarrhea. In the next week of, what initially appeared as typical HUS, she developed MOF, including ileus, pancreatitis, hepatitis, coma and ARDS, accompanied by hemodynamic instability and extreme leukocytosis. Nonetheless, the girl made a complete recovery after one month of the disease. She was successfully treated in the intensive care unit and significant improvement was noticed after plasmapheresis and continuous veno-venous hemodialysis.Conclusions: Early start of plasmapheresis and meticulous supportive treatment in the intensive care unit, including renal placement therapy, may be the therapy of choice in severe cases of HUS presented by MOF. Monitoring of prognostic factors is important for early performance of appropriate diagnostic and therapeutical interventions.


2016 ◽  
Vol 2 (12) ◽  
Author(s):  
Alpha Oumar BAH ◽  
Mamadou Cellou BALDE ◽  
Amadou BAH ◽  
Alpha Oumar BARRY

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