Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0606201104 ◽

2007 ◽

Vol 104 (7) ◽

pp. 2495-2500 ◽

Author(s):

M. Urushitani ◽

S. A. Ezzi ◽

J.-P. Julien

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Therapeutic Effects ◽

Lateral Sclerosis

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Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation

Neuropathology ◽

10.1046/j.1440-1789.2001.00361.x ◽

2001 ◽

Vol 21 (1) ◽

pp. 82-92 ◽

Author(s):

Noriyuki Shibata

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Lateral Sclerosis

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Faculty Opinions recommendation of Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1102304.558337 ◽

2008 ◽

Author(s):

Mark Bothwell

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Transgenic Mice ◽

Specific Expression ◽

Lateral Sclerosis

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Biochemical and Therapeutic Effects of Antioxidants in the Treatment of Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis

Current Drug Targets - CNS & Neurological Disorders ◽

10.2174/1568007033482959 ◽

2003 ◽

Vol 2 (2) ◽

pp. 95-107 ◽

Author(s):

Vincenzo Matteo ◽

Ennio Esposito

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Therapeutic Effects ◽

Alzheimers Disease ◽

Parkinsons Disease ◽

Lateral Sclerosis

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Two novel mutations in the gene for coppe zinc superoxide dismutase in UK families with amyotrophic lateral sclerosis

Human Molecular Genetics ◽

10.1093/hmg/4.7.1239 ◽

1995 ◽

Vol 4 (7) ◽

pp. 1239-1240 ◽

Author(s):

Z. E. Enayat ◽

R. W. Orrell ◽

A. Claus ◽

A. Ludolph ◽

R. Bachus ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Novel Mutations ◽

Zinc Superoxide Dismutase ◽

Lateral Sclerosis

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Early Activation of Antioxidant Mechanisms in Muscle of Mutant Cu/Zn-Superoxide Dismutase-Linked Amyotrophic Lateral Sclerosis Mice

Annals of the New York Academy of Sciences ◽

10.1196/annals.1299.102 ◽

2003 ◽

Vol 1010 (1) ◽

pp. 552-556 ◽

Author(s):

NATASA JOKIC ◽

FRANCK DI SCALA ◽

LUC DUPUIS ◽

FREDERIQUE RENE ◽

ANDRE MULLER ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Early Activation ◽

Antioxidant Mechanisms ◽

Lateral Sclerosis

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Expression of a familial amyotrophic lateral sclerosis-associated mutant human superoxide dismutase in yeast leads to decreased mitochondrial electron transport

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2004.08.009 ◽

2004 ◽

Vol 431 (2) ◽

pp. 207-214 ◽

Author(s):

Michael R. Gunther ◽

Reyna VanGilder ◽

Jing Fang ◽

Diana S. Beattie

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Electron Transport ◽

Familial Amyotrophic Lateral Sclerosis ◽

Lateral Sclerosis

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Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis

Acta Neuropathologica ◽

10.1007/s00401-011-0805-3 ◽

2011 ◽

Vol 121 (5) ◽

pp. 623-634 ◽

Author(s):

Karin Forsberg ◽

Peter M. Andersen ◽

Stefan L. Marklund ◽

Thomas Brännström

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Superoxide Dismutase 1 ◽

Lateral Sclerosis

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Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.94.14.7606 ◽

1997 ◽

Vol 94 (14) ◽

pp. 7606-7611 ◽

Author(s):

L. I. Bruijn ◽

M. F. Beal ◽

M. W. Becher ◽

J. B. Schulz ◽

P. C. Wong ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Hydroxyl Radicals ◽

Tyrosine Nitration ◽

Superoxide Dismutase 1 ◽

Familial Als ◽

Lateral Sclerosis

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Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2007.05053.x ◽

2008 ◽

Vol 104 (4) ◽

pp. 993-1005 ◽

Author(s):

Yeo Kyoung Oh ◽

Ki Soon Shin ◽

Junying Yuan ◽

Shin Jung Kang

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Superoxide Dismutase 1 ◽

Neuro2a Cells ◽

Lateral Sclerosis

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Superoxide Dismutase Activity, Oxidative Damage, and Mitochondrial Energy Metabolism in Familial and Sporadic Amyotrophic Lateral Sclerosis

Journal of Neurochemistry ◽

10.1111/j.1471-4159.1993.tb07478.x ◽

1993 ◽

Vol 61 (6) ◽

pp. 2322-2325 ◽

Author(s):

Allen C. Bowling ◽

Jorg B. Schulz ◽

Robert H. Brown ◽

M. Flint Beal

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Energy Metabolism ◽

Oxidative Damage ◽

Superoxide Dismutase Activity ◽

Sporadic Amyotrophic Lateral Sclerosis ◽

Mitochondrial Energy Metabolism ◽

Lateral Sclerosis

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