Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1016558108 ◽

2011 ◽

Vol 108 (17) ◽

pp. 6727-6732 ◽

Author(s):

K. J. Frankowski ◽

V. Setola ◽

J. M. Evans ◽

B. Neuenswander ◽

B. L. Roth ◽

...

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ChemInform Abstract: Polymer-Assisted Solution-Phase Synthesis under Combined Ultrasound and Microwave Irradiation: Preparation of Î±,Î²-Unsaturated Esters and Carboxylic Acids, Key Intermediates of Novel Sigma Ligands.

10.1002/chin.201004074 ◽

2010 ◽

Vol 41 (4) ◽

Author(s):

D. Rossi ◽

M. Urbano ◽

A. Carnevale Baraglia ◽

M. Serra ◽

F. Bergamelli ◽

...

Keyword(s):

Microwave Irradiation ◽

Carboxylic Acids ◽

Solution Phase ◽

Phase Synthesis ◽

Unsaturated Esters ◽

Solution Phase Synthesis ◽

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Relationship between modulation of the cerebellorubrospinal system in the in vitro turtle brain and changes in motor behavior in rats: effects of novel sigma ligands

Brain Research Bulletin ◽

10.1016/s0361-9230(99)00029-5 ◽

1999 ◽

Vol 48 (5) ◽

pp. 497-508 ◽

Author(s):

Rae R. Matsumoto ◽

Wayne D. Bowen ◽

Brian R. de Costa ◽

James C. Houk

Keyword(s):

Motor Behavior ◽

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Effects of NMDA receptor antagonists and sigma ligands on the acquisition of conditioned fear in mice

Psychopharmacology ◽

10.1007/bf02244550 ◽

1991 ◽

Vol 104 (1) ◽

pp. 27-34 ◽

Author(s):

D. J. Sanger ◽

D. Joly

Keyword(s):

Nmda Receptor ◽

Conditioned Fear ◽

Nmda Receptor Antagonists ◽

Receptor Antagonists ◽

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Suppression of vasoactive intestinal peptide (VIP)-induced increases in ileal ion transport by sigma ligands

Gastroenterology ◽

10.1016/0016-5085(95)28304-8 ◽

1995 ◽

Vol 108 (4) ◽

pp. A1000

Keyword(s):

Ion Transport ◽

Vasoactive Intestinal Peptide ◽

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Regional differences of the effects of sigma ligands on extracellular dopamine metabolites in rat brain: an in vivo microdialysis study

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)49602-9 ◽

1992 ◽

Vol 58 ◽

pp. 369

Author(s):

Keiko Matsunaga ◽

Kiyoshi Matsuno ◽

Shiro Mita

Keyword(s):

Rat Brain ◽

Regional Differences ◽

In Vivo Microdialysis ◽

Dopamine Metabolites ◽

Extracellular Dopamine ◽

Sigma Ligands ◽

Microdialysis Study

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Immunosuppressant effects of sigma ligands in a brain

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)40198-4 ◽

1998 ◽

Vol 76 ◽

pp. 17

Author(s):

Yoshihiro Nakata ◽

Sayori Sugita ◽

Atsuko Inoue ◽

Izumi Hide

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Sigma ligands modify cholinergic agonist-induced Ca~+-activated dopamine release in differentiated rat pheochromocytoma (PC12) cells

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)49483-3 ◽

1992 ◽

Vol 58 ◽

pp. 330

Author(s):

Naoki Sagi ◽

Hideko Yamamoto ◽

Takashi Moroji

Keyword(s):

Dopamine Release ◽

Cholinergic Agonist ◽

Pheochromocytoma Pc12 ◽

Pheochromocytoma Pc12 Cells ◽

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Neuroendocrinological and neurochemical effects of sigma ligands

Neuropharmacology ◽

10.1016/0028-3908(92)90026-l ◽

1992 ◽

Vol 31 (2) ◽

pp. 157-162 ◽

Author(s):

G.A. Gudelsky ◽

J.F. Nash

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Sigma ligands bind in the guinea pig and rat brain to a high-affinity dextromethorphan site, which is allosterically modulated by ropizine and phenytoin

European Journal of Pharmacology ◽

10.1016/0014-2999(90)93669-h ◽

1990 ◽

Vol 183 (6) ◽

pp. 2146 ◽

Author(s):

M. Klein ◽

G. Zhou ◽

J.M. Musacchio

Keyword(s):

Rat Brain ◽

High Affinity ◽

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Sigma ligands as potential psychotropic drugs

Journal of Psychopharmacology ◽

10.1177/026988119400800112 ◽

1994 ◽

Vol 8 (1) ◽

pp. 64-65 ◽

Author(s):

B.E. Leonard ◽

C.D. Nicholson

Keyword(s):

Psychotropic Drugs ◽

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