Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

Allosteric Modulation ◽

Disease Treatment ◽

Potential Approach ◽

Group Iii ◽

P2.118 Allosteric modulation of group III metabotropic glutamate receptor 4: a potential neuroprotective approach for the treatment of Parkinson's disease

Parkinsonism & Related Disorders ◽

10.1016/s1353-8020(09)70469-9 ◽

2009 ◽

Vol 15 ◽

pp. S121 ◽

Cited By ~ 1

Author(s):

M. Betts ◽

M. O'Neill ◽

S. Mitchell ◽

S. Duty

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Allosteric Modulation ◽

Group Iii ◽

Synergy between l-DOPA and a novel positive allosteric modulator of metabotropic glutamate receptor 4: Implications for Parkinson's disease treatment and dyskinesia

Neuropharmacology ◽

10.1016/j.neuropharm.2012.03.022 ◽

2013 ◽

Vol 66 ◽

pp. 158-169 ◽

Cited By ~ 63

Author(s):

Khaled-Ezaheir Bennouar ◽

Michelle A. Uberti ◽

Christophe Melon ◽

Maria D. Bacolod ◽

Hermogenes N. Jimenez ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Allosteric Modulator ◽

Positive Allosteric Modulator ◽

Disease Treatment ◽

Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: implications for Parkinson’s disease treatment

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2009.06036.x ◽

2009 ◽

Vol 109 (4) ◽

pp. 1096-1105 ◽

Cited By ~ 42

Author(s):

Dario Cuomo ◽

Giuseppina Martella ◽

Emanuela Barabino ◽

Paola Platania ◽

Daniela Vita ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Receptor Subtype ◽

Disease Treatment ◽

Metabotropic Glutamate ◽

Gaba Transmission

Group III and subtype 4 metabotropic glutamate receptor agonists: Discovery and pathophysiological applications in Parkinson's disease

Neuropharmacology ◽

10.1016/j.neuropharm.2012.05.026 ◽

2013 ◽

Vol 66 ◽

pp. 53-64 ◽

Cited By ~ 47

Author(s):

M. Amalric ◽

S. Lopez ◽

C. Goudet ◽

G. Fisone ◽

G. Battaglia ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Group Iii ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Glutamate Receptor Agonists

Changes in metabotropic glutamate receptor expression in the basal ganglia of Parkinson's disease models

Neuroscience Research ◽

10.1016/s0168-0102(00)81571-0 ◽

2000 ◽

Vol 38 ◽

pp. S121

Author(s):

M Takada

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Basal Ganglia ◽

Glutamate Receptor ◽

Receptor Expression ◽

Disease Models ◽

Blockade of metabotropic glutamate receptor 5 attenuates axonal degeneration in 6-hydroxydopamine-induced model of Parkinson's disease

Molecular and Cellular Neuroscience ◽

10.1016/j.mcn.2020.103572 ◽

2021 ◽

Vol 110 ◽

pp. 103572

Author(s):

Jian-Nan Zhang ◽

Yan-Lin Huang ◽

Hui-Min Yang ◽

Yuan Wang ◽

Li Gu ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Axonal Degeneration ◽

Metabotropic Glutamate ◽

6 Hydroxydopamine

Intrapallidal metabotropic glutamate receptor activation in a rat model of Parkinson's disease: Behavioral and histological analyses

Brain Research ◽

10.1016/j.brainres.2008.01.051 ◽

2008 ◽

Vol 1203 ◽

pp. 189-196 ◽

Cited By ~ 13

Author(s):

Takashi Agari ◽

Takao Yasuhara ◽

Toshihiro Matsui ◽

Satoshi Kuramoto ◽

Akihiko Kondo ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Rat Model ◽

Receptor Activation ◽

Reduction of l-DOPA-Induced Dyskinesia by the Selective Metabotropic Glutamate Receptor 5 Antagonist 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Lesioned Macaque Model of Parkinson's Disease

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.166629 ◽

2010 ◽

Vol 333 (3) ◽

pp. 865-873 ◽

Cited By ~ 98

Author(s):

Tom H. Johnston ◽

Susan H. Fox ◽

Matthew J. McIldowie ◽

Matthew J. Piggott ◽

Jonathan M. Brotchie

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Metabotropic Glutamate ◽

Macaque Model

Blockade of metabotropic glutamate receptor 5 protects against DNA damage in a rotenone-induced Parkinson's disease model

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2015.09.017 ◽

2015 ◽

Vol 89 ◽

pp. 567-580 ◽

Cited By ~ 15

Author(s):

Ning Xia ◽

Qian Zhang ◽

Shu Ting Wang ◽

Li Gu ◽

Hui Min Yang ◽

...

Keyword(s):

Parkinson’S Disease ◽

Dna Damage ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Disease Model ◽

Triptolide up-regulates metabotropic glutamate receptor 5 to inhibit microglia activation in the lipopolysaccharide-induced model of Parkinson’s disease

Brain Behavior and Immunity ◽

10.1016/j.bbi.2018.04.006 ◽

2018 ◽

Vol 71 ◽

pp. 93-107 ◽

Cited By ~ 10

Author(s):

Yi-Ying Huang ◽

Qian Zhang ◽

Jian-Nan Zhang ◽

Ya-Nan Zhang ◽

Li Gu ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Glutamate Receptor ◽

Microglia Activation ◽