The Selenoenzyme Phospholipid Hydroperoxide Glutathione Peroxidase Controls the Activity of the 15-Lipoxygenase with Complex Substrates and Preserves the Specificity of the Oxygenation Products

Kerstin Schnurr; Jutta Belkner; Fulvio Ursini; Tankred Schewe; Hartmut Kühn

doi:10.1074/jbc.271.9.4653

The Selenoenzyme Phospholipid Hydroperoxide Glutathione Peroxidase Controls the Activity of the 15-Lipoxygenase with Complex Substrates and Preserves the Specificity of the Oxygenation Products

Journal of Biological Chemistry ◽

10.1074/jbc.271.9.4653 ◽

1996 ◽

Vol 271 (9) ◽

pp. 4653-4658 ◽

Cited By ~ 127

Author(s):

Kerstin Schnurr ◽

Jutta Belkner ◽

Fulvio Ursini ◽

Tankred Schewe ◽

Hartmut Kühn

Keyword(s):

Glutathione Peroxidase ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide

Substituting Selenocysteine for Catalytic Cysteine 41 Enhances Enzymatic Activity of Plant Phospholipid Hydroperoxide Glutathione Peroxidase Expressed inEscherichia coli

Journal of Biological Chemistry ◽

10.1074/jbc.m004985200 ◽

2000 ◽

Vol 275 (37) ◽

pp. 28715-28721 ◽

Cited By ~ 55

Author(s):

Stephane Hazebrouck ◽

Luc Camoin ◽

Zehava Faltin ◽

Arthur Donny Strosberg ◽

Yuval Eshdat

Keyword(s):

Glutathione Peroxidase ◽

Enzymatic Activity ◽

Inescherichia Coli ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide ◽

Catalytic Cysteine

Purification of a cytosolic enzyme from human liver with phospholipid hydroperoxide glutathione peroxidase activity

International Journal of Biochemistry ◽

10.1016/0020-711x(94)90097-3 ◽

1994 ◽

Vol 26 (10-11) ◽

pp. 1279-1286 ◽

Cited By ~ 12

Author(s):

Stephen J. Chambers ◽

Nigel Lambert ◽

Gary Williamson

Keyword(s):

Glutathione Peroxidase ◽

Peroxidase Activity ◽

Human Liver ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Glutathione Peroxidase Activity ◽

Phospholipid Hydroperoxide

Phospholipid Hydroperoxide Glutathione Peroxidase: A Selenoprotein Distinct from Glutathione Peroxidase

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury ◽

10.1007/978-1-4615-3520-1_18 ◽

1993 ◽

pp. 75-78

Author(s):

R. Brigelius-Flohé ◽

R. Schuckelt ◽

W. StraβBurgher ◽

F. Ursini ◽

B. Wolf ◽

...

Keyword(s):

Glutathione Peroxidase ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide

The Phospholipid Hydroperoxide Glutathione Peroxidase: A Peroxidation Inhibition Enzyme

Cellular Antioxidant Defense Mechanisms ◽

10.1201/9780429289309-3 ◽

2019 ◽

pp. 69-76

Author(s):

Fulvio Ursini

Keyword(s):

Glutathione Peroxidase ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide

Isolation,Partial Purification and Characterization of Phospholipid Hydroperoxide Glutathione Peroxidase(Phgpx Enzyme from Oryza Sativa Seedlings

Journal of Chemical Engineering & Process Technology ◽

10.4172/2157-7048.1000120 ◽

2011 ◽

Vol 02 (05) ◽

Author(s):

Om Prakash Verma ◽

Pankaj Kumar Ojha ◽

Shashi B Bailey

Keyword(s):

Oryza Sativa ◽

Glutathione Peroxidase ◽

Partial Purification ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Purification And Characterization ◽

Phospholipid Hydroperoxide

Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals

Biological Chemistry ◽

10.1515/bc.2007.130 ◽

2007 ◽

Vol 388 (10) ◽

Cited By ~ 78

Author(s):

Marcus Conrad ◽

Manuela Schneider ◽

Alexander Seiler ◽

Georg W. Bornkamm

Keyword(s):

Glutathione Peroxidase ◽

Physiological Role ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide

PO6-174 THE EFFECT OF OVER-EXPRESSING AND DOWN-EXPRESSING PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE ON ATHEROSCLEROSIS IN APOLIPOPROTEIN E-DEFICIENT MICE

Atherosclerosis Supplements ◽

10.1016/s1567-5688(07)71184-4 ◽

2007 ◽

Vol 8 (1) ◽

pp. 60

Author(s):

H. Yang ◽

L.C. Zhou ◽

Z.M. Guo

Keyword(s):

Glutathione Peroxidase ◽

Apolipoprotein E ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide ◽

Deficient Mice

Docosahexaenoic (DHA) modulates phospholipid-hydroperoxide glutathione peroxidase (Gpx4) gene expression to ensure self-protection from oxidative damage in hippocampal cells

Frontiers in Physiology ◽

10.3389/fphys.2015.00203 ◽

2015 ◽

Vol 6 ◽

Cited By ~ 20

Author(s):

Verónica Casañas-Sánchez ◽

José A. Pérez ◽

Noemí Fabelo ◽

David Quinto-Alemany ◽

Mario L. Díaz

Keyword(s):

Gene Expression ◽

Glutathione Peroxidase ◽

Oxidative Damage ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide ◽

Self Protection

Molecular cloning and expression of a phospholipid hydroperoxide glutathione peroxidase homolog in Oryza sativa

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ◽

10.1016/s0167-4781(00)00152-4 ◽

2000 ◽

Vol 1493 (1-2) ◽

pp. 225-230 ◽

Cited By ~ 51

Author(s):

Wen-Jun Li ◽

Hai Feng ◽

Jing-Hua Fan ◽

Ri-Qing Zhang ◽

Nan-Ming Zhao ◽

...

Keyword(s):

Oryza Sativa ◽

Glutathione Peroxidase ◽

Molecular Cloning ◽

Cloning And Expression ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide

Phospholipase C-dependent hydrolysis of phosphatidylcholine hydroperoxides to diacylglycerol hydroperoxides and its reduction by phospholipid hydroperoxide glutathione peroxidase

Redox Report ◽

10.1179/135100002125000154 ◽

2002 ◽

Vol 7 (1) ◽

pp. 29-33 ◽

Cited By ~ 6

Author(s):

Y. Kambayashi ◽

S. Takekoshi ◽

K. Watanabe ◽

Y. Yamamoto

Keyword(s):

Glutathione Peroxidase ◽

Phospholipase C ◽

Phospholipid Hydroperoxide Glutathione Peroxidase ◽

Phospholipid Hydroperoxide ◽

Hydrolysis Of