scholarly journals Involvement of Gangliosides in Glycosylphosphatidylinositol-anchored Neuronal Cell Adhesion Molecule TAG-1 Signaling in Lipid Rafts

2000 ◽  
Vol 275 (44) ◽  
pp. 34701-34709 ◽  
Author(s):  
Kohji Kasahara ◽  
Kazutada Watanabe ◽  
Kosei Takeuchi ◽  
Harumi Kaneko ◽  
Atsuhiko Oohira ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Lipid Rafts ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neuronal Cell ◽  
Neuronal Cell Adhesion Molecule

scholarly journals Association of the neuronal cell adhesion molecule (NRCAM) gene variants with autism

2008 ◽  
Vol 12 (01) ◽  
pp. 1 ◽  
Author(s):  
Tetsuya Marui ◽  
Ikuko Funatogawa ◽  
Shinko Koishi ◽  
Kenji Yamamoto ◽  
Hideo Matsumoto ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neuronal Cell ◽  
Gene Variants ◽  
Neuronal Cell Adhesion Molecule

Presenilin 1 interacts with a neuronal cell adhesion molecule and mediates its intracellular trafficking

2000 ◽  
Vol 21 ◽  
pp. 133 ◽  
Author(s):  
Wim G. Annaert ◽  
Christine Boeve ◽  
Cary Esselens ◽  
Greet Snellings ◽  
Kathleen Craessaerts ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Intracellular Trafficking ◽  
Cell Adhesion Molecule ◽  
Neuronal Cell ◽  
Presenilin 1 ◽  
Neuronal Cell Adhesion Molecule

The neuronal cell adhesion molecule L1CAM as a therapeutic targe in breast cancer.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. e21138-e21138
Author(s):  
J. Jassem ◽  
R. Duchnowska ◽  
W. Biernat ◽  
L. M. Evans ◽  
D. P. Fitzgerald ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neuronal Cell ◽  
Neuronal Cell Adhesion Molecule

Influence of neuronal cell adhesion molecule (NCAM1) variants on suicidal behaviour and correlated traits

2010 ◽  
Vol 179 (2) ◽  
pp. 222-225 ◽  
Author(s):  
Ina Giegling ◽  
Alberto Chiesa ◽  
Laura Mandelli ◽  
Sara Gibiino ◽  
Annette M. Hartmann ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Suicidal Behaviour ◽  
Cell Adhesion Molecule ◽  
Neuronal Cell ◽  
Correlated Traits ◽  
Neuronal Cell Adhesion Molecule

scholarly journals Sodium channel β1 and β3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain

2001 ◽  
Vol 154 (2) ◽  
pp. 427-434 ◽  
Author(s):  
Charlotte F. Ratcliffe ◽  
Ruth E. Westenbroek ◽  
Rory Curtis ◽  
William A. Catterall
Keyword(s):  
Cell Adhesion ◽  
Sodium Channel ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neuronal Cell ◽  
Nodes Of Ranvier ◽  
Neuronal Cell Adhesion Molecule ◽  
Fibronectin Type Iii ◽  
A Cell ◽  
Fibronectin Type

Sequence homology predicts that the extracellular domain of the sodium channel β1 subunit forms an immunoglobulin (Ig) fold and functions as a cell adhesion molecule. We show here that β1 subunits associate with neurofascin, a neuronal cell adhesion molecule that plays a key role in the assembly of nodes of Ranvier. The first Ig-like domain and second fibronectin type III–like domain of neurofascin mediate the interaction with the extracellular Ig-like domain of β1, confirming the proposed function of this domain as a cell adhesion molecule. β1 subunits localize to nodes of Ranvier with neurofascin in sciatic nerve axons, and β1 and neurofascin are associated as early as postnatal day 5, during the period that nodes of Ranvier are forming. This association of β1 subunit extracellular domains with neurofascin in developing axons may facilitate recruitment and concentration of sodium channel complexes at nodes of Ranvier.

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