Characterization of EHop-016, Novel Small Molecule Inhibitor of Rac GTPase

Rac Gtpase ◽

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0307512101 ◽

2004 ◽

Vol 101 (20) ◽

pp. 7618-7623 ◽

Cited By ~ 749

Author(s):

Y. Gao ◽

J. B. Dickerson ◽

F. Guo ◽

J. Zheng ◽

Y. Zheng

Keyword(s):

Small Molecule ◽

Rational Design ◽

Rac Gtpase ◽

Faculty Opinions recommendation of Rational design and characterization of a Rac GTPase-specific small molecule inhibitor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1019249.216541 ◽

2004 ◽

Author(s):

J Silvio Gutkind

Keyword(s):

Small Molecule ◽

Rational Design ◽

Rac Gtpase ◽

Characterization of EHop‐016, a novel small molecule inhibitor of Rac GTPase

The FASEB Journal ◽

10.1096/fasebj.26.1_supplement.lb243 ◽

2012 ◽

Vol 26 (S1) ◽

Author(s):

Tessa Winifred Humphries-Bickley ◽

Linette Castillo-Pichardo ◽

Brenda L. Montalvo-Ortiz ◽

Eliud Hernandez ◽

Cornelis P. Vlaar ◽

...

Keyword(s):

Small Molecule ◽

Rac Gtpase ◽

Faculty Opinions recommendation of Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1283961.751061 ◽

2009 ◽

Author(s):

Marie-France Carlier

Keyword(s):

Small Molecule ◽

Identification And Characterization

Actin Assembly ◽

Molecule Inhibitor ◽

Rational Design and Applications of a Rac GTPase–Specific Small Molecule Inhibitor

Methods in Enzymology - Regulators and Effectors of Small GTPases: Rho Family ◽

10.1016/s0076-6879(06)06043-5 ◽

2006 ◽

pp. 554-565 ◽

Cited By ~ 48

Author(s):

Huzoor Akbar ◽

Jose Cancelas ◽

David A. Williams ◽

Jie Zheng ◽

Yi Zheng

Keyword(s):

Small Molecule ◽

Rational Design ◽

Rac Gtpase ◽

Abstract LB-209: Identification and characterization of small molecule inhibitor of Wnt canonical pathway in a glioma setting.

10.1158/1538-7445.am2012-lb-209 ◽

2012 ◽

Author(s):

Alessandra De Robertis ◽

Silvia Valensin ◽

Marco Rossi ◽

Margherita Verani ◽

Patrizia Tunici ◽

...

Keyword(s):

Small Molecule ◽

Identification And Characterization

Canonical Pathway ◽

Molecule Inhibitor ◽

Abstract 3228: Characterization of a novel, orally bioavailable, potent and highly selective small molecule inhibitor of PERK: A tool to probe the biphasic concentration-dependent induction of ER stress in models of multiple myeloma and B-cell lymphoma

10.1158/1538-7445.am2014-3228 ◽

2014 ◽

Author(s):

Ian Stansfield ◽

Yannick Ligny ◽

Yvan Simonnet ◽

Christophe Demestre ◽

Nathalie Amblard ◽

...

Keyword(s):

Multiple Myeloma ◽

Er Stress ◽

B Cell ◽

Small Molecule ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Molecule Inhibitor ◽

Orally Bioavailable

Abstract 4484: Discovery and in vitro characterization of AMG 510–a potent and selective covalent small-molecule inhibitor of KRASG12C

10.1158/1538-7445.sabcs18-4484 ◽

2019 ◽

Cited By ~ 1

Author(s):

Anne Y. Saiki ◽

Kevin Gaida ◽

Karen Rex ◽

Pragathi Achanta ◽

Tisha San Miguel ◽

...

Keyword(s):

Small Molecule ◽

In Vitro Characterization ◽

398 POSTER Discovery and characterization of a small molecule inhibitor of human Cdc7 kinase

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(06)70403-7 ◽

2006 ◽

Vol 4 (12) ◽

pp. 122

Author(s):

C. Santocanale ◽

A. Montagnoli ◽

P. Tenca ◽

M. Menichincheri ◽

B. Valsasina ◽

...

Keyword(s):

Small Molecule ◽

Molecule Inhibitor ◽

Cdc7 Kinase

Characterization of DDRI-18 (3,3′-(1H,3′H-5,5′-bibenzo[d]imidazole-2,2′-diyl)dianiline), a novel small molecule inhibitor modulating the DNA damage response

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2012.01977.x ◽

2012 ◽

Vol 167 (1) ◽

pp. 141-150 ◽

Cited By ~ 6

Author(s):

DW Jun ◽

YS Jeong ◽

HJ Kim ◽

K-C Jeong ◽

S Kim ◽

...

Keyword(s):

Dna Damage ◽

Dna Damage Response ◽

Small Molecule ◽

Molecule Inhibitor ◽

Damage Response