Three-Component Reaction of Triphenylphosphine, Dialkyl Acetylenedicarboxylate, and 2-Aminothiazole or 2-Aminobenzothiazole in the Presence of Arylglyoxals: An Efficient One-Pot Synthesis of Highly Functionalized Pyrroles

2012 ◽  
Vol 42 (13) ◽  
pp. 1877-1884 ◽  
Author(s):  
Mohammad Anary-Abbasinejad ◽  
Hamidreza Dehghanpour Farashah ◽  
Alireza Hassanabadi ◽  
Hossein Anaraki-Ardakani ◽  
Nasim Shams
Keyword(s):  
One Pot ◽  
Dialkyl Acetylenedicarboxylate ◽  
One Pot Synthesis ◽  
Three Component Reaction

Intramolecular Diels–Alder and [3+2] Cycloaddition Reactions in the One-Pot Synthesis of Epoxypyrrolo[3,4-g]indazoles

Synthesis ◽  
2019 ◽  
Vol 51 (15) ◽  
pp. 2936-2944 ◽  
Author(s):  
Abdolali Alizadeh ◽  
Kaveh Amir Ashjaee Asalemi ◽  
Mohammadreza Halvagar
Keyword(s):  
Cycloaddition Reaction ◽  
Diels Alder ◽  
Second Step ◽  
Cycloaddition Reactions ◽  
One Pot ◽  
Dialkyl Acetylenedicarboxylate ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
Final Compound ◽  
The One

A one-pot approach for the synthesis of epoxypyrrolo[3,4-g]indazoles is presented. The first step was initiated by a three-component reaction of an isocyanide, a dialkyl acetylenedicarboxylate, and 2-furancarboxylic acid, and led to 1,3-dioxoepoxyisoindole, followed by the addition of hydrazonoyl chloride through a [3+2]-cycloaddition reaction in the second step. The key step in the formation of final compound involves a bicyclization strategy through intramolecular Diels–Alder­ (IMDA) reaction.

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

Isocyanide-based three component reaction for synthesis of highly cyano substituted furan derivatives

RSC Advances ◽  
2016 ◽  
Vol 6 (32) ◽  
pp. 26783-26790 ◽  
Author(s):  
Hamid Reza Safaei ◽  
Farbod Dehbozorgi
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Furan Derivatives ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction

A rapid and efficient solvent-free one-pot synthesis of novel alkyl amino aryl furan tricarbonitrile derivatives is described under catalyst-free conditions.

ChemInform Abstract: Rhodium Catalyzed Three-Component Reaction of Aldehyde, Boronic Acid, and Sulfonamides: A Facile One-Pot Synthesis of Diarylmethylamines.

ChemInform ◽  
2015 ◽  
Vol 46 (10) ◽  
pp. no-no
Author(s):  
Ponnam Satyanarayana ◽  
Ganapam Manohar Reddy ◽  
Hariharasarma Maheswaran ◽  
Mannepalli Lakshmi Kantam
Keyword(s):  
Boronic Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Three Component Reaction
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