New Chiral Borohydride Based Reducing Agent: Asymmetric Reduction of 9-Anthryl Trifluoromethyl Ketone and Other Carbonyl Compounds

1998 ◽  
Vol 28 (1) ◽  
pp. 99-108 ◽  
Author(s):  
Dilip K. Maiti ◽  
Pranab K. Bhattacharya
Keyword(s):  
Carbonyl Compounds ◽  
Asymmetric Reduction ◽  
Reducing Agent

Enantioselective Radical Functionalization of Imines and Iminium Intermediates via Visible Light Photoredox Catalysis

Synthesis ◽  
2020 ◽  
Author(s):  
Jia-Jia Zhao ◽  
Hong-Hao Zhang ◽  
Shouyun Yu
Keyword(s):  
Visible Light ◽  
Asymmetric Synthesis ◽  
Carbonyl Compounds ◽  
Asymmetric Reduction ◽  
Chemical Transformations ◽  
Photoredox Catalysis ◽  
Radical Coupling ◽  
Mild Conditions ◽  
Iminium Ions ◽  
Radical Functionalization

Visible light photoredox catalysis has recently emerged as a powerful tool for the development of new and valuable chemical transformations under mild conditions. Visible-light promoted enantioselective radical transformations of imines and iminium intermediates provide new opportunities for the asymmetric synthesis of amines and asymmetric β-functionalization of unsaturated carbonyl compounds. In this review, the advance in the catalytic asymmetric radical functionalization of imines, as well as iminium intermediates, are summarized. 1 Introduction 2 The enantioselective radical functionalization of imines 2.1 Asymmetric reduction 2.2 Asymmetric cyclization 2.3 Asymmetric addition 2.4 Asymmetric radical coupling 3 The enantioselective radical functionalization of iminium ions 3.1 Asymmetric radical alkylation 3.2 Asymmetric radical acylation 4 Conclusion

Sodium borohydride: A versatile reagent in the reductive N-monoalkylation of α-amino acids and α-amino methyl esters

2002 ◽  
Vol 80 (7) ◽  
pp. 779-788 ◽  
Author(s):  
Giancarlo Verardo ◽  
Paola Geatti ◽  
Elena Pol ◽  
Angelo G Giumanini
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Sodium Borohydride ◽  
Carbonyl Compounds ◽  
Condensation Reaction ◽  
Methyl Esters ◽  
Reducing Agent ◽  
Reductive Condensation ◽  
Versatile Reagent

α-Amino acids and α-amino methyl esters are easily converted to their N-monoalkyl derivatives by a reductive condensation reaction using several carbonyl compounds in the presence of sodium borohydride. This reducing agent has shown a wide versatility with minor but essential procedural variations. The reaction allows the α-monodeuterium labeling of the new N-substituent by use of sodium borodeuteride.Key words: α-amino acid, α-amino methyl esters, sodium borohydride, reductive N-monoalkylation, carbonyl compounds.

Deoxygenation of carbonyl compounds using an alcohol as an efficient reducing agent catalyzed by oxo-rhenium complexes

2016 ◽  
Vol 18 (9) ◽  
pp. 2675-2681 ◽  
Author(s):  
Joana R. Bernardo ◽  
Ana C. Fernandes
Keyword(s):  
Catalytic System ◽  
Carbonyl Compounds ◽  
Reducing Agent ◽  
Rhenium Complexes

The catalytic system 3-pentanol/ReOCl3(SMe2)(OPPh3) was very efficient for the deoxygenation of carbonyl compounds.

ChemInform Abstract: Asymmetric Reduction of α-(Dimethylthiocarbamoylthio) Carbonyl Compounds with Bakers′ Yeast.

ChemInform ◽  
1989 ◽  
Vol 20 (6) ◽  
Author(s):  
S. TSUBOI ◽  
N. KOHARA ◽  
K. DOI ◽  
M. UTAKA ◽  
A. TAKEDA
Keyword(s):  
Carbonyl Compounds ◽  
Asymmetric Reduction

Enzymatic Asymmetric Reduction of Carbonyl Compounds

2016 ◽  
pp. 307-330 ◽  
Author(s):  
Tomoko Matsuda ◽  
Rio Yamanaka ◽  
Kaoru Nakamura
Keyword(s):  
Carbonyl Compounds ◽  
Asymmetric Reduction
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